AMPK alpha 1 Antibody (2B7) - BSA Free

AMPK alpha 1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increases the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using NBP2-22127	Applications	Species
Mehanna ET, Khalaf SS, Mesbah NM Et al. Anti-oxidant, anti-apoptotic, and mitochondrial regulatory effects of selenium nanoparticles against vancomycin induced nephrotoxicity in experimental rats Life sciences 2021-10-26 [PMID: 34715137] (WB, Rat)	WB	Rat
Nguyen K, Rivera A, Alzoubi M et al. Evaluation of liver kinase B1 downstream signaling expression in various breast cancers and relapse free survival after systemic chemotherapy treatment Oncotarget 2021-05-25 [PMID: 34084284] (WB)	WB
Jassim, A H, Cavanaugh, M Et al. Transcorneal Electrical Stimulation Reduces Neurodegenerative Process in a Mouse Model of Glaucoma. Ann Biomed Eng 2021-02-01 [PMID: 32974756] (ICC/IF, Human)	ICC/IF	Human
Harun-Or-Rashid M, Pappenhagen N, Zubricky R et al. MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma Neurobiol. Dis. 2020-05-15 [PMID: 32422282] (WB, Mouse)	WB	Mouse
Vila IK, Park MK, Setijono SR et al A muscle-specific UBE2O/AMPK alpha 2 axis promotes insulin resistance and metabolic syndrome in obesity JCI Insight 2019-07-11 [PMID: 31292296] (WB, Mouse)	WB	Mouse
Korponay TC, Balnis J, Vincent CE et al. High CO2 downregulates skeletal muscle protein anabolism via AMPK alpha 2-mediated depressed ribosomal biogenesis Am. J. Respir. Cell Mol. Biol. 2019-07-02 [PMID: 31264907]
Harun-Or-Rashid M, Inman DM. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. J Neuroinflammation. 2018-11-13 [PMID: 30424795] (WB, Mouse)	WB	Mouse
Chauhan AS, Liu X, Jing J et al. STIM2 interacts with AMPk and regulates calcium-induced AMPk activation. FASEB J. 2018-10-18 [PMID: 30335546] (ICC/IF, Human)	ICC/IF	Human
Dai S, Dulcey AE, Hu X et al. Methyl-B-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017-06-14 [PMID: 28613987] (WB, Human)	WB	Human
Vila IK, Yao Y, Kim G et al. A UBE2O-AMPKalpha2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy. Cancer Cell. 2017-02-13 [PMID: 28162974] (Mouse)		Mouse
Xiao Y, Kwong M, Daemen A et al. Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. PLoS ONE 2016-10-06 [PMID: 27711204]
Chen Y, Duan Y et al. Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2015-01-04 [PMID: 25810299] (WB, Human)	WB	Human
Show All 12 Publications. Collapse Publications.

Array NBP2-22127

• AMPK alpha 1 Antibodies
• AMPK alpha 1 ELISA Kit
• AMPK alpha 1 Lysate
• AMPK alpha 1 Proteins
• AMPK alpha 1 ELISAs