AMPK alpha 1 Products

Description

The 5'-AMP-activated protein kinase (AMPK), a member of the SNF1 (sucrose non-fermentor) kinase family (1) AMPK is a heterotrimeric protein comprising alpha (63 kDa), beta (38 kDa) and gamma (38 kDa) subunits. The alpha subunit is the catalytic subunit (which requires phosphorylation to be active) (2-3). Beta and gamma are non-catalytic subunits, although they have been found to interact with the active subunit in liver. AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (4). AMPK also appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways

Bioinformatics

Entrez	105787 Mouse 5562 Human 65248 Rat
Uniprot	AAH12622 Human AAH48980.1 Human NM_006251 Human NP_006242 Human Q13131 Human
Product By Gene ID	5562
Alternate Names	AMP -activate kinase alpha 1 subunit AMP-activated protein kinase, catalytic, alpha-1,5'-AMP-activated protein kinase catalytic subunit alpha-1 AMPK alpha 1,5'-AMP-activated protein kinase, catalytic alpha-1 chain AMPK subunit alpha-1 AMPK AMPK1 AMPKa1 EC 2.7.11 EC 2.7.11.1 MGC33776 MGC57364 protein kinase, AMP-activated, alpha 1 catalytic subunit

Research Areas for AMPK alpha 1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Autophagy
Cancer
Hypoxia
MAP Kinase Signaling
mTOR Pathway
Phospho-Specific
Signal Transduction
Translation Control

Related AMPK alpha 1 Blog Posts

Check out the latest blog posts on AMPK alpha 1.

AMPK Alpha 1 and lipid metabolism of adipocytes AMP-activated protein kinase (AMPK) is best known as a sensor of oxidative stress.  AMPK is activated by increased intracellular AMP levels, which are a result of alterations in cellular metabolism from causes such as hypoxia, changes in ATP, sene...    Read more.

Read more AMPK alpha 1 related blogs.