Nurr1/NGFI-B beta/NR4A2 Antibody - BSA Free

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: IHC, IP.

Showing Publications 1 - 3 of 3.

Publications using NB110-40415	Applications	Species
Servaas NH, Hiddingh S, Chouri E et al. Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+?Dendritic Cell Dysregulation in Systemic Sclerosis Arthritis & rheumatology (Hoboken, N.J.) 2023-02-01 [PMID: 36482877]
Lilley CM, Alarcon A, Ngo MH et al. Orphan Nuclear Receptor NR4A2 Is Constitutively Expressed in Cartilage and Upregulated in Inflamed Synovium From hTNF-Alpha Transgenic Mice Frontiers in Pharmacology 2022-04-20 [PMID: 35529439] (IHC)	IHC
Luo Y, Xing F, Guiliano R et al. Identification of a Novel Nurr1-Interacting Protein. J Neurosci;28(37):9277-9286. 2008-01-01 [PMID: 18784308] (IP, Mouse)	IP	Mouse

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	IHC-P	Mouse	05/23/2018	View Summary Application Immunohistochemistry-Paraffin Sample Tested joints Species Mouse Lot 2930 Comments Comments antigen retrieval working concentration: 4ug/mL

Array NB110-40415

• Nurr1/NGFI-B beta/NR4A2 Antibodies
• Nurr1/NGFI-B beta/NR4A2 Proteins