Nurr1/NGFI-B beta/NR4A2 Products

Description

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

Bioinformatics

Uniprot	AAH66890 Human NM_173173 Human NP_006177 Human NP_006177.1 Human P43354 Human
Product By Gene ID	4929
Alternate Names	human homolog of nuclear receptor subfamily 4, group A, member 2 orphan nuclear receptor NR4A2 Orphan nuclear receptor NURR1 T-cell nuclear receptor NOT transcriptionally inducible nuclear receptor related 1 Transcriptionally-inducible nuclear receptor

Research Areas for Nurr1/NGFI-B beta/NR4A2

Find related products by research area and learn more about each of the different research areas below.

Immune System Diseases
Immunology