Rabbit IgG Isotype Control

IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Bovine, Rabbit.

We have publications tested in 9 applications: Chemotaxis, FLOW, Flow Cytometry, ICC/IF, IF/IHC, IHC, IHC-P, In vitro, WB.

Showing Publications 1 - 10 of 55. Show All 55 Publications. Collapse Publications.

Publications using NBP2-24891	Applications	Species
Ines Köhler, Cecilia Bivik Eding, Nada-Katarina Kasic, Deepti Verma, Charlotta Enerbäck NOS2-derived low levels of NO drive psoriasis pathogenesis Cell Death & Disease 2024-06-26 [PMID: 38926337]
Sahoo M, Singh R, Kumar P et al. Novel pathologic findings and viral antigen distribution in cattle and buffalo calves naturally infected with Foot-and-Mouth disease virus The veterinary quarterly 2023-12-01 [PMID: 37733477] (IHC, Bovine)	IHC	Bovine
Wang S, Chen X, Guo S et al. CXCR4, regulated by HIF1A, promotes endometrial breakdown via CD45+ leukocyte recruitment in a mouse model of menstruation Reproductive biology 2023-06-29 [PMID: 37392490] (IHC)	IHC
Aakeroy L, Cheng CW, Sustova P et al. Identification of exercise-regulated genes in mice exposed to cigarette smoke Physiological reports 2022-11-01 [PMID: 36324300] (IHC-P, Mouse)	IHC-P	Mouse
Thomason EJ, SuArez-Pozos E, Afshari FS et al. Deletion of the Sodium-Dependent Glutamate Transporter GLT-1 in Maturing Oligodendrocytes Attenuates Myelination of Callosal Axons During a Postnatal Phase of Central Nervous System Development Frontiers in cellular neuroscience 2022-06-03 [PMID: 35722615] (FLOW)	FLOW
Mundal SB, Rakner JJ, Silva GB et al. Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction International journal of molecular sciences 2022-02-10 [PMID: 35216082]
Boontanrart M Flipping the Hemoglobin Switch and Discovering Regulators Involved in Fetal Hemoglobin Reactivation Thesis 2020-01-01 (Chemotaxis)	Chemotaxis
Boontanrart MY, Stehli G, Banovic M, Schroeder M ATF4 mediates fetal globin upregulation in response to reduced beta-globin bioRxiv 2020-01-01 (Chemotaxis, Human)	Chemotaxis	Human
Cavalli E, Fisch P, Formica F et al. A comparative study of cartilage engineered constructs in immunocompromised, humanized and immunocompetent mice Journal of Immunology and Regenerative Medicine 2018-09-01 (IF/IHC, Human)	IF/IHC	Human
Anne L. Rosen, Michael A. Lint, Dayne H. Voelker, Nicole M. Gilbert, Christopher P. Tomera, Jesús Santiago-Borges, Meghan A. Wallace, Thomas J. Hannan, Carey-Ann D. Burnham, Scott J. Hultgren, Andrew L. Kau, Matthew R. Chapman Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice mBio 2024-02-01 [PMID: 38270443]
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fatima Al-Shahrour, Timothy P. Cash, Tamara Tchkonia, James L. Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2 Nature Cancer 2024-01-24 [PMID: 38267628]
Kumagai S, Koyama S, Itahashi K Et al. Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments Cancer Cell 2022-01-29 [PMID: 35090594] Details: Citation using the PE version of this antibody.
Tossetta G, Fantone S, Gesuita R et al. AT-rich interactive domain 1A (ARID1A) cannot be considered a morphological marker for prostate cancer progression: A pilot study Acta histochemica 2022-01-14 [PMID: 35038591] (IHC-P)	IHC-P
Vu BG, Moye-Rowley WS Azole-resistant alleles of ERG11 in Candida glabrata trigger activation of the Pdr1 and Upc2A transcription factors Antimicrobial agents and chemotherapy 2022-01-10 [PMID: 35007132]
El-Shehawy R, Luecke-Johansson S, Ribbenstedt A, Gorokhova E Microbiota-Dependent and -Independent Production of l-Dopa in the Gut of Daphnia magna mSystems 2021-11-09 [PMID: 34751589] (IF/IHC)	IF/IHC
Montes de Oca R, Alavi AS, Vitali N et al. Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo Molecular Cancer Therapeutics 2021-10-01 [PMID: 34253590] (Flow Cytometry)	Flow Cytometry
Dorschner BW, Wiedemuth R, Funke AC et al. Listening to the Whispers in Neuroimmune Crosstalk: A Comprehensive Workflow to Investigate Neurotrophin Receptor p75NTR Under Endogenous, Low Abundance Conditions Frontiers in Immunology 2021-04-16 [PMID: 33936068]
Yoshimura T, Inokuchi Y, Mutou C et al. Age-related decline in the taurine content of the skin in rodents Amino acids 2021-02-20 [PMID: 33608821] (IF/IHC, Mouse) Details: Antibody used for negative controls	IF/IHC	Mouse
Qi X, Wang F, Chun C et al. A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs) Physiol Rep 2020-11-01 [PMID: 33242364]
Oikawa K, Teixeira LBC, Keikhosravi A et al. Microstructure and resident cell-types of the feline optic nerve head resemble that of humans Exp Eye Res 2020-10-19 [PMID: 33091431] (ICC/IF)	ICC/IF
Cayli S, Sahin C, Sanci TO, Nakkas H Inhibition of p97/VCP function leads to defective autophagosome maturation, cell cycle arrest and apoptosis in mouse Sertoli cells Theriogenology 2020-09-15 [PMID: 32966945] (ICC/IF)	ICC/IF
Mietus CJ, Lackner TJ, Karvelis PS et al. Abnormal Microvascular Architecture, Fibrosis, and Pericyte Characteristics in the Calf Muscle of Peripheral Artery Disease Patients with Claudication and Critical Limb Ischemia J Clin Med 2020-08-08 [PMID: 32784470] (ICC/IF, Human, Bovine)	ICC/IF	Human, Bovine
Boontanrart MY, SchrOder MS, Stehli GM et al. ATF4 Regulates MYB to Increase gamma-Globin in Response to Loss of beta-Globin Cell Rep 2020-01-01 [PMID: 32755585] (Chemotaxis, Human)	Chemotaxis	Human
Kumagai S, Togashi Y, Sakai C et al. An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells Immunity 2020-07-14 [PMID: 32640259] Details: Citation using the PE format of this antibody.
Zhang, X, Wang, H Et al. Enterovirus A71 Oncolysis of Malignant Gliomas. Mol Ther 2020-06-03 [PMID: 32304669] (WB)	WB
Sakumoto R, Hayashi KG, Hosoe M et al. Pregnancy-associated changes of Peroxisome Proliferator-Activated Receptor Delta (PPARD) and Cytochrome P450 Family 21 Subfamily A Member 2 (CYP21A2) expression in the bovine corpus luteum J. Reprod. Dev. 2020-02-07 [PMID: 32037375] (IF/IHC, Bovine)	IF/IHC	Bovine
Carpenter MD, Hu Q, Bond AM et al. Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes Nat Commun 2020-01-24 [PMID: 31980629] (Chemotaxis, Mouse)	Chemotaxis	Mouse
Hirayama H, Sakumoto R, Koyama K et al. Expression of C-C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition J. Reprod. Dev. 2020-02-14 [PMID: 31761882]
Zhou G, Liao M et al. Cyclophilin A contributes to aortopathy induced by postnatal loss of smooth muscle TGFBR1. FASEB J 2019-01-10 [PMID: 31311317] (IF/IHC, Mouse)	IF/IHC	Mouse
Eustace NJ, Anderson JC, Langford CP et al. Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma. Int J Oncol. 2019-03-29 [PMID: 30942445] (WB, Rabbit) Details: Citation using the Azide Free form of this antibody.	WB	Rabbit
Rinne P, Lyytikainen LP, Raitoharju E et al. Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis- Tampere Vascular Study. Sci Rep. 2018-10-10 [PMID: 30305673] (IHC-P, Mouse)	IHC-P	Mouse
Vazquez Rodriguez G, Abrahamsson A, Jensen LDE et al. Adipocytes Promote Early Steps of Breast Cancer Cell Dissemination via Interleukin-8 Front. Immunol 2018-07-30 [PMID: 30105032] (ICC/IF, Human) Details: This citation used the Azide and BSA Free version of this antibody.	ICC/IF	Human
Sakurai T, kamio k, Sasaki k et al. Imaging Mass Microscopy of kidneys from Azithromycin-Treated Rats with Phospholipidosis. Am. J. Pathol. 2018-07-06 [PMID: 29981744] (IF/IHC, Rabbit)	IF/IHC	Rabbit
Adamson Samantha E, Polanowska-Grabowska Renata, Marqueen Kathryn et al. Deficiency of Dab2 (Disabled Homolog 2) in Myeloid Cells Exacerbates Inflammation in Liver and Atherosclerotic Plaques in LDLR (Low-Density Lipoprotein Receptor)-Null Mice-Brief Report. Arteriosclerosis, Thrombosis, and Vascular Biology 2018-03-29 [PMID: 29599136]
Sakumoto R, Hayashi KG, Fujii S et al. Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early Pregnancy. Int J Mol Sci 2017-03-31 [PMID: 28362325] (IF/IHC)	IF/IHC
Hayashi KG, Hosoe M, Kizaki K et al. Differential gene expression profiling of endometrium during the mid-luteal phase of the estrous cycle between a repeat breeder (RB) and non-RB cows. Reprod. Biol. Endocrinol. 2017-03-23 [PMID: 28335821] (IF/IHC, Bovine)	IF/IHC	Bovine
Subramanian K1, Bergman P, Henriques-Normark B. Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils. J Innate Immun. [PMID: 28241127] (FLOW, Human) Details: Citation using the FITC form of this antibody.	FLOW	Human
Sareddy GR, Viswanadhapalli S, Surapaneni P et al. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2016-11-28 [PMID: 27893719]
Sakumoto R, Hayashi KG, Saito S et al. Comparison of the global gene expression profiles in the bovine endometrium between summer and autumn. J. Reprod. Dev. 2015-05-19 [PMID: 25994242] (IHC-P, Bovine)	IHC-P	Bovine
Nishimura Y, Takiguchi S, Ito S, Itoh K. EGF-stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib-resistant human lung cancer cell line Int. J. Oncol. 2015-04-01 [PMID: 25653196]
Zimmermann M, Aguilera FB, Castellucci M et al. Chromatin remodelling and autocrine TNFalpha are required for optimal interleukin-6 expression in activated human neutrophils. Nat Commun. [PMID: 25616107] (FLOW) Details: Citation using the PE form of this antibody.	FLOW
Freund A, Zhong Fl, Venteicher As et al. Proteostatic Control of Telomerase Function through TRiC-Mediated Folding of TCAB1. Cell. [PMID: 25467444] (In vitro) Details: Citation using the Azide Free form of this antibody.	In vitro
Sakumoto R, Hayashi KG, Hosoe M et al. Gene expression profiles in the bovine corpus luteum (CL) during the estrous cycle and pregnancy: possible roles of chemokines in regulating CL function during pregnancy. J Reprod Dev 2015-01-01 [PMID: 25382605] (IF/IHC)	IF/IHC
Janssen E, Ozcan E, Liadaki K et al. TRIF Signaling Is Essential for TLR4-Driven IgE Class Switching. J. Immunol. 2014-03-15 [PMID: 24532577] (Chemotaxis, Mouse)	Chemotaxis	Mouse
Takanashi Naoya, Tomosada Yohsuke, Villena Julio et al. Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia coli-mediated inflammation. BMC Microbiol. [PMID: 23497067] (ICC/IF) Details: Citation using the Alexa Fluor 488 form of this antibody.	ICC/IF
Turco F, Sarnelli G, Cirillo C et al. Enteroglial-derived S100B protein integrates bacteria-induced Toll-like receptor signalling in human enteric glial cells. Gut. [PMID: 23292665] (ICC/IF, Human) Details: Citation using the Alexa Fluor 488 form of this antibody.	ICC/IF	Human
Scheitz Cornelia Johanna Franziska, Lee Tae Seung, McDermitt David James, Tumbar Tudorita. Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer. EMBO J. 2012-11-05 [PMID: 23034403] (Chemotaxis)	Chemotaxis
Shimazu T, Villena J, Tohno M et al. Immunobiotic Lactobacillus jensenii elicits anti-inflammatory activity in porcine intestinal epithelial cells by modulating negative regulators of the Toll-like receptor signaling pathway. Infect Immun. 2012-01-01 [PMID: 22083706] Details: Cat no 20304E (normal rabbit IgG isotype control): Flow (cell surface), Fig 4C (porcine intestinal epitheliocyte cell line).
Chiba Eriko, Villena Julio, Hosoya Shoichi et al. A newly established bovine intestinal epithelial cell line is effective for in vitro screening of potential antiviral immunobiotic microorganisms for cattle. Res Vet Sci. [PMID: 22047818] (ICC/IF) Details: Citation using the Azide Free form of this antibody.	ICC/IF
Hosoya Shoichi, Villena Julio, Shimazu Tomoyuki et al. Immunobiotic lactic acid bacteria beneficially regulate immune response triggered by poly(I:C) in porcine intestinal epithelial cells. Vet Res. [PMID: 22046952] (IF/IHC) Details: Citation using the Azide Free form of this antibody.	IF/IHC
Liebelt B, Papapetrou P, Ali A et al. Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2. Neuroscience. [PMID: 20083167] (Rat) Details: Citation using the Azide Free form of this antibody.		Rat
Wu J, Meng Z, Jiang M et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. [PMID: 19922426] Details: Citation using the PE/Cy5 form of this antibody.
Guo L, Urban JF, Zhu J et al. Elevating calcium in Th2 cells activates multiple pathways to induce IL-4 transcription and mRNA stabilization. J Immunol. 2008-09-15 [PMID: 18768853] Details: Flow (intracellular), mouse CD4 T cells, Fig. 4C.
Kurzrock EA, Lieu DK, Degraffenried LA et al. Label-retaining cells of the bladder: candidate urothelial stem cells. Am J Physiol Renal Physiol. 2008-06-01 [PMID: 18367656] Details: Flow (cell surface), rat urothelial cells, Figs. 4, 5.
Patole PS, Pawar RD, Lech M et al. Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice. Nephrol Dial Transplant. 2006-11-01 [PMID: 16954173] Details: For IHC (frozen) on mouse kidney sections (Fig. 5): TLR3 (IMG-516), TLR7 (IMG-581A), TLR9 (IMG-431) and Rabbit IgG isotype control antibody (20304). For Flow (Intacellular) and Flow (Cell surface) on J774 mouse macrophage-like cell line (Fig 6B): TLR7 (IMG-581A), TLR9 (IMG-431) and Rabbit IG isotype control antibody (20304).
Show All 55 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Ranveer Singh	ChIP	Human	06/18/2014	View Summary Application Chromatin Immunoprecipitation Sample Tested Cross-linked chromatin from HEK 293T cells Species Human

Array NBP2-24891

• IgG Antibodies
• IgG ELISA Kits
• IgG Isotype Controls
• IgG Kit
• IgG Proteins
• IgG Antibodies
• IgG ELISAs