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Nurr1/NGFI-B beta/NR4A2 Antibody [Alexa Fluor® 750]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 750

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-40415AF350
Alexa Fluor 405
NB110-40415AF405
Alexa Fluor 488
NB110-40415AF488
Alexa Fluor 532
NB110-40415AF532
Alexa Fluor 594
NB110-40415AF594
Alexa Fluor 647
NB110-40415AF647
Alexa Fluor 700
NB110-40415AF700
Allophycocyanin
NB110-40415APC
Biotin
NB110-40415B
CoraFluor 1
NB110-40415CL1
DyLight 350
NB110-40415UV
DyLight 405
NB110-40415V
DyLight 488
NB110-40415G
DyLight 550
NB110-40415R
DyLight 594
NB110-40415DL594
DyLight 650
NB110-40415C
DyLight 680
NB110-40415FR
DyLight 755
NB110-40415IR
FITC
NB110-40415F
HRP
NB110-40415H
Janelia Fluor 525
NB110-40415JF525
Janelia Fluor 549
NB110-40415JF549
Janelia Fluor 585
NB110-40415JF585
Janelia Fluor 635
NB110-40415JF635
Janelia Fluor 646
NB110-40415JF646
Janelia Fluor 669
NB110-40415JF669
PE
NB110-40415PE
PerCP
NB110-40415PCP
Unconjugated
NB110-40415
mFluor Violet 450 SE
NB110-40415MFV450
mFluor Violet 500 SE
NB110-40415MFV500
mFluor Violet 610 SE
NB110-40415MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-40415
BSA Free
NB110-40415
BSA Free
NB110-40415SS
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Nurr1/NGFI-B beta/NR4A2 Antibody [Alexa Fluor® 750] Summary

Immunogen
Synthetic peptide comprising residues 513-526 [TERHGLKEPKRVEE] of the human Nurr1 protein. Based on 100% sequence homology, this antibody is also expected to cross react with rat and mouse Nurr1.
Specificity
This is specific to the Nurr1 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR4A2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human and Rat. Other species not yet tested. Mouse reactivity reported in scientific literature (PMID: 18784308).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Nurr1/NGFI-B beta/NR4A2 Antibody [Alexa Fluor® 750]

  • human homolog of
  • NGFI-B beta
  • NOT
  • NR4A2
  • nuclear receptor subfamily 4, group A, member 2
  • Nurr1
  • orphan nuclear receptor NR4A2
  • Orphan nuclear receptor NURR1
  • T-cell nuclear receptor NOT
  • TINUR
  • transcriptionally inducible nuclear receptor related 1
  • Transcriptionally-inducible nuclear receptor

Background

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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[Biotin]
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Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, KO, WB

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Bioinformatics

Gene Symbol NR4A2