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Nurr1/NGFI-B beta/NR4A2 Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-40415AF350
Alexa Fluor 405
NB110-40415AF405
Alexa Fluor 488
NB110-40415AF488
Alexa Fluor 532
NB110-40415AF532
Alexa Fluor 594
NB110-40415AF594
Alexa Fluor 647
NB110-40415AF647
Alexa Fluor 700
NB110-40415AF700
Alexa Fluor 750
NB110-40415AF750
Allophycocyanin
NB110-40415APC
Biotin
NB110-40415B
CoraFluor 1
NB110-40415CL1
DyLight 350
NB110-40415UV
DyLight 405
NB110-40415V
DyLight 488
NB110-40415G
DyLight 550
NB110-40415R
DyLight 594
NB110-40415DL594
DyLight 650
NB110-40415C
DyLight 680
NB110-40415FR
DyLight 755
NB110-40415IR
FITC
NB110-40415F
HRP
NB110-40415H
Janelia Fluor 525
NB110-40415JF525
Janelia Fluor 549
NB110-40415JF549
Janelia Fluor 585
NB110-40415JF585
Janelia Fluor 635
NB110-40415JF635
Janelia Fluor 669
NB110-40415JF669
PE
NB110-40415PE
PerCP
NB110-40415PCP
Unconjugated
NB110-40415
mFluor Violet 450 SE
NB110-40415MFV450
mFluor Violet 500 SE
NB110-40415MFV500
mFluor Violet 610 SE
NB110-40415MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-40415
BSA Free
NB110-40415
BSA Free
NB110-40415SS
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Nurr1/NGFI-B beta/NR4A2 Antibody [Janelia Fluor® 646] Summary

Immunogen
Synthetic peptide comprising residues 513-526 [TERHGLKEPKRVEE] of the human Nurr1 protein. Based on 100% sequence homology, this antibody is also expected to cross react with rat and mouse Nurr1.
Specificity
This is specific to the Nurr1 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR4A2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human and Rat. Other species not yet tested. Mouse reactivity reported in scientific literature (PMID: 18784308).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Nurr1/NGFI-B beta/NR4A2 Antibody [Janelia Fluor® 646]

  • human homolog of
  • NGFI-B beta
  • NOT
  • NR4A2
  • nuclear receptor subfamily 4, group A, member 2
  • Nurr1
  • orphan nuclear receptor NR4A2
  • Orphan nuclear receptor NURR1
  • T-cell nuclear receptor NOT
  • TINUR
  • transcriptionally inducible nuclear receptor related 1
  • Transcriptionally-inducible nuclear receptor

Background

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Western Blot SLC6A3/DAT1 Antibody (mAb16)
Immunohistochemistry-Paraffin SLC6A3/DAT1 Antibody (mAb16)
(3 Reviews)
(14 Publications)
Species: Hu(-), Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
POMC Antibody
NB100-1533
Flow Cytometry POMC Antibody
Immunohistochemistry POMC Antibody
Immunohistochemistry POMC Antibody
(10 Publications)
Species: Hu, Mu, Po, Rt, Sh
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GDNF [Unconjugated]
212-GD
Bioactivity GDNF [Unconjugated]
SDS-PAGE GDNF [Unconjugated]
SEC-MALS GDNF [Unconjugated]
(209 Publications)
Species: Hu
Applications: Bind, BA
Sonic Hedgehog/Shh
[Unconjugated]
464-SH
Bioactivity Sonic Hedgehog/Shh [Unconjugated]
SDS-PAGE Sonic Hedgehog/Shh [Unconjugated]
SEC-MALS Sonic Hedgehog/Shh [Unconjugated]
(65 Publications)
Species: Mu
Applications: BA
CREB [p Ser133]
[Biotin]
DYC2510-2
N/A CREB [p Ser133] [Biotin]
N/A CREB [p Ser133] [Biotin]
N/A CREB [p Ser133] [Biotin]
(9 Publications)
Species: Hu, Mu, Rt
Applications: ELISA
alpha-Synuclein
Antibody
NBP2-15365
Immunohistochemistry-Frozen alpha-Synuclein Antibody
Western Blot alpha-Synuclein Antibody
Immunohistochemistry-Frozen alpha-Synuclein Antibody
(1 Review)
(12 Publications)
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FGF-8
[Unconjugated]
423-F8
SDS-PAGE FGF-8 [Unconjugated]
Bioactivity FGF-8 [Unconjugated]
Cell Culture FGF-8 [Unconjugated]
(1 Review)
(62 Publications)
Species: Hu, Mu
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CYP11B2 Antibody
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BDNF [HRP]
DBD00
N/A BDNF [HRP]
N/A BDNF [HRP]
N/A BDNF [HRP]
(100 Publications)
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Antibody (7G4) [Uncon ...
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TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(807 Publications)
Species: Hu
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LMX1b Antibody
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Immunohistochemistry-Paraffin LMX1b Antibody
(1 Publication)
Species: Hu, Mu, Rt
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EGR1 Antibody
[Unconjugated]
AF2818
EGR1 Antibody [Unconjugated]
(13 Publications)
Species: Hu
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c-Fos Antibody
(2H2)
NBP2-50037
Knockout Validated c-Fos Antibody (2H2)
Immunocytochemistry/ Immunofluorescence c-Fos Antibody (2H2)
Immunocytochemistry/ Immunofluorescence c-Fos Antibody (2H2)
(1 Review)
(19 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, KO, WB

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Bioinformatics

Gene Symbol NR4A2