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XRCC4 Antibody (OTI4H9) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
OTI4H9
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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XRCC4 Antibody (OTI4H9) [Janelia Fluor® 646] Summary

Immunogen
Full-length protein expressed in 293T cell transfected with human XRCC4 expression vector.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
XRCC4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for XRCC4 Antibody (OTI4H9) [Janelia Fluor® 646]

  • complementing defective, repair in Chinese hamster
  • X-ray repair complementing defective repair in Chinese hamster cells 4
  • X-ray repair cross-complementing protein 4

Background

XRCC4 is encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for XRCC4 Antibody (NBP2-74896JF646) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for XRCC4 Antibody (NBP2-74896JF646)

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Blogs on XRCC4.

Ku70: The DNA's Mr. Fix-it
Ku70, known by several synonyms including X-ray repair cross-complementing, 5'-deoxyribose-5-phosphate lyase Ku70 protein 6, 70 kDa subunit of Ku antigen, XRCC6, and G22P1, is a 70 kDa protein that was shown to be involved in multiple cellular pathway...  Read full blog post.

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Bioinformatics

Gene Symbol XRCC4