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STEP Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-81893AF350
Alexa Fluor 405
NBP2-81893AF405
Alexa Fluor 488
NBP2-81893AF488
Alexa Fluor 532
NBP2-81893AF532
Alexa Fluor 594
NBP2-81893AF594
Alexa Fluor 647
NBP2-81893AF647
Alexa Fluor 700
NBP2-81893AF700
Alexa Fluor 750
NBP2-81893AF750
CoraFluor 1
NBP2-81893CL1
DyLight 350
NBP2-81893UV
DyLight 405
NBP2-81893V
DyLight 488
NBP2-81893G
DyLight 550
NBP2-81893R
DyLight 594
NBP2-81893DL594
DyLight 650
NBP2-81893C
DyLight 680
NBP2-81893FR
DyLight 755
NBP2-81893IR
FITC
NBP2-81893F
HRP
NBP2-81893H
Janelia Fluor 525
NBP2-81893JF525
Janelia Fluor 549
NBP2-81893JF549
Janelia Fluor 585
NBP2-81893JF585
Janelia Fluor 635
NBP2-81893JF635
Janelia Fluor 646
NBP2-81893JF646
Janelia Fluor 669
NBP2-81893JF669
PerCP
NBP2-81893PCP
Unconjugated
NBP2-81893
mFluor Violet 450 SE
NBP2-81893MFV450
mFluor Violet 500 SE
NBP2-81893MFV500
mFluor Violet 610 SE
NBP2-81893MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-81893
BSA Free
NBP2-81893
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STEP Antibody [Biotin] Summary

Immunogen
STEP antibody was raised against an 18 amino acid peptide near the amino terminus of human STEP. The immunogen is located within amino acids 180 - 230 of STEP. Amino Acid Squence: LRTPPEPPTPLPPEDRRQ
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPN5
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for STEP Antibody [Biotin]

  • EC 3.1.3.48
  • FLJ14427
  • Neural-specific protein-tyrosine phosphatase
  • protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
  • protein-tyrosine phosphatase striatum-enriched
  • PTPN5
  • STEP
  • STEPPTPSTEP
  • Striatum-enriched protein-tyrosine phosphatase
  • tyrosine-protein phosphatase non-receptor type 5

Background

The protein tyrosine phosphatase non-receptor type 5 or striatum-enriched protein-tyrosine phosphatase (STEP) protein is part of a family of protein tyrosine phosphatases enriched within the CNS, and is a key component of the NMDAR complex. It is expressed within dopaminoceptive neurons in the CNS and particularly enriched within the basal ganglia and related structures. STEP61 is the membrane-associated isoform and STEP46 is the cytosolic protein. In response to transient hypoxia-ischemia in the brain, STEP61 is proteolytically cleaved by calpain, thereby releasing a smaller isoform, STEP33.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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STEP Antibody
[Biotin]
NBP2-81893B
STEP Antibody [Biotin]
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PTPN5