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Reg1A Antibody (431202) [Unconjugated]

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AGS human gastric adenocarcinoma cell line was stained with Rat Anti-Human Reg1A Monoclonal Antibody (Catalog # MAB4937, filled histogram) or isotype control antibody (Catalog # MAB0061, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG F(ab')2 Secondary Antibody (Catalog # F0113). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.
AGS human gastric adenocarcinoma cell line was stained with Rat Anti-Human Reg1A Monoclonal Antibody (Catalog # MAB4937, filled histogram) or isotype control antibody (Catalog # MAB0061, open histogram), followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, CyTOF-ready, Flow
Clone
431202
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC4937U-100UG
Alexa Fluor 350
FAB4937U
Alexa Fluor 405
FAB4937V
Alexa Fluor 405
IC4937V-100UG
Alexa Fluor 488
IC4937G-100UG
Alexa Fluor 488
FAB4937G
Alexa Fluor 532
FAB4937X
Alexa Fluor 594
IC4937T-100UG
Alexa Fluor 594
FAB4937T
Alexa Fluor 647
FAB4937R
Alexa Fluor 647
IC4937R-100UG
Alexa Fluor 700
IC4937N-100UG
Alexa Fluor 700
FAB4937N
Alexa Fluor 750
IC4937S-100UG
Alexa Fluor 750
FAB4937S
Allophycocyanin
FAB4937A
Biotin
FAB4937B
DyLight 350
FAB4937D
DyLight 405
FAB4937E
DyLight 488
FAB4937K
DyLight 550
FAB4937L
DyLight 594
FAB4937M
DyLight 650
FAB4937W
DyLight 680
FAB4937Y
DyLight 755
FAB4937Z
FITC
FAB4937F
HRP
FAB4937H
Janelia Fluor 549
FAB4937I
Janelia Fluor 646
FAB4937J
PE
FAB4937P
PerCP
FAB4937C
mFluor Violet 450 SE
FAB4937MFV450
mFluor Violet 500 SE
FAB4937MFV500
mFluor Violet 610 SE
FAB4937MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB4937-SP
Carrier Free
IC4937R-100UG
Carrier Free
IC4937N-100UG
Carrier Free
IC4937V-100UG
Carrier Free
IC4937U-100UG
Carrier Free
IC4937T-100UG
Carrier Free
IC4937S-100UG
Carrier Free
IC4937G-100UG
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Reg1A Antibody (431202) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human Reg1A
Gln23-Asn166
Accession # P05451
Specificity
Detects human Reg1A in Western blots. Shows 5% cross-reactivity with recombinant human (rh) Reg1B and no cross-reactivity with rhReg3A, recombinant mouse Reg1, or recombinant rat Reg1.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
REG1A
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB4937 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Reg1A Antibody (431202) [Unconjugated]

  • ICRF
  • Islet cells regeneration factor
  • Islet of Langerhans regenerating protein
  • lithostathine-1-alpha
  • P19
  • pancreatic stone protein, secretory
  • Pancreatic thread protein
  • protein-X
  • PSP
  • PSPS
  • PSPS1
  • PTP
  • REG
  • Reg1A
  • REG-1-alpha
  • Regenerating islet-derived protein 1-alpha
  • Regenerating protein I alpha

Background

Reg1A, also known as PTP, PSP, and lithostathine, is a member of the Reg family of secreted proteins with a C-type lectin domain. Due to variable glycosylation, pancreatic Reg1A exists as multiple species of 16‑18 kDa. Reg1A promotes the maintenance and growth of pancreatic islet beta -cells and intestinal villi. It is up‑regulated in pancreatitis and some carcinomas. Reg1A is an antigenic target in autoimmune diabetes. Human Reg1A shares 65%‑68% aa sequence identity with mouse and rat Reg1A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Reg1A Antibody
(431202) [Unconjugate
MAB4937
Reg1A Antibody (431202) [Unconjugated]
Species: Hu
Applications: WB, CyTOF-ready, Flow

Publications for Reg1A Antibody (MAB4937)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IHC, Western Blot.


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(1)
Western Blot
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Bioinformatics

Gene Symbol REG1A
Uniprot