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STEP Antibody (23E5) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clone
23E5
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB300-202AF350
Alexa Fluor 405
NB300-202AF405
Alexa Fluor 488
NB300-202AF488
Alexa Fluor 532
NB300-202AF532
Alexa Fluor 594
NB300-202AF594
Alexa Fluor 647
NB300-202AF647
Alexa Fluor 700
NB300-202AF700
Alexa Fluor 750
NB300-202AF750
Allophycocyanin
NB300-202APC
Biotin
NB300-202B
CoraFluor 1
NB300-202CL1
DyLight 350
NB300-202UV
DyLight 405
NB300-202V
DyLight 488
NB300-202G
DyLight 550
NB300-202R
DyLight 594
NB300-202DL594
DyLight 650
NB300-202C
DyLight 680
NB300-202FR
DyLight 755
NB300-202IR
FITC
NB300-202F
HRP
NB300-202H
Janelia Fluor 525
NB300-202JF525
Janelia Fluor 549
NB300-202JF549
Janelia Fluor 585
NB300-202JF585
Janelia Fluor 635
NB300-202JF635
Janelia Fluor 646
NB300-202JF646
Janelia Fluor 669
NB300-202JF669
PE
NB300-202PE
PerCP
NB300-202PCP
Unconjugated
NB300-202
mFluor Violet 450 SE
NB300-202MFV450
mFluor Violet 500 SE
NB300-202MFV500
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STEP Antibody (23E5) [mFluor Violet 610 SE] Summary

Immunogen
A synthetic peptide of rat STEP46 (amino acids 57-74: MCTPGCNEEGFGYLVSPR)
Localization
Cytoplasmic
Specificity
NB300-202 is specific for STEP61, STEP46, STEP38, and STEP20.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PTPN5
Purity
Unpurified
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Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Unpurified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for STEP Antibody (23E5) [mFluor Violet 610 SE]

  • EC 3.1.3.48
  • FLJ14427
  • Neural-specific protein-tyrosine phosphatase
  • protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
  • protein-tyrosine phosphatase striatum-enriched
  • PTPN5
  • STEP
  • STEPPTPSTEP
  • Striatum-enriched protein-tyrosine phosphatase
  • tyrosine-protein phosphatase non-receptor type 5

Background

The protein tyrosine phosphatase non-receptor type 5 or striatum-enriched protein-tyrosine phosphatase (STEP) protein is part of a family of protein tyrosine phosphatases enriched within the CNS, and is a key component of the NMDAR complex. It is expressed within dopaminoceptive neurons in the CNS and particularly enriched within the basal ganglia and related structures. STEP61 is the membrane-associated isoform and STEP46 is the cytosolic protein. In response to transient hypoxia-ischemia in the brain, STEP61 is proteolytically cleaved by calpain, thereby releasing a smaller isoform, STEP33.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB300-202MFV610
STEP Antibody (23E5) [mFluor Violet 610 SE]
Species: Hu, Mu, Rt
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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PTPN5