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PTPRO Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining in human kidney and skeletal muscle tissues . Corresponding PTPRO RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human kidney shows strong membranous positivity in cells in glomeruli.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human cerebral cortex shows very weak cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human colon shows moderate cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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PTPRO Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TRVNISYWEGKDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPRO
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
IHC reported in scientific literature (PMID: 25826083). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PTPRO Protein (NBP1-81826PEP)
Publications
Read Publication using
NBP1-81826 in the following applications:

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (84%). Human reactivity reported in scientific literature (PMID: 25826083).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PTPRO Antibody

  • EC 3.1.3.48
  • GLEPP1PTPROt
  • Glomerular epithelial protein 1
  • phosphotyrosine phosphatase U2
  • protein tyrosine phosphatase PTP-U2
  • Protein tyrosine phosphatase U2
  • protein tyrosine phosphatase, receptor type, O
  • PTPase U2
  • PTP-oc
  • PTP-U2glomerular epithelial protein-1
  • PTPU2osteoclastic transmembrane protein-tyrosine phosphatase
  • receptor-type protein tyrosine phosphatase O
  • receptor-type tyrosine-protein phosphatase O
  • R-PTP-O

Background

PTPRO encodes a receptor-type protein tyrosine phosphatase containing a single intracellular catalytic domain with a characteristic signature motif. The gene product, which has a transmembrane domain, is an integral membrane protein. Several alternatively spliced transcript variants, some of which encode different isoforms of the protein, have been described. These variants exhibit tissue-specific expression. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PTPRO Antibody (NBP1-81826)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.


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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PTPRO