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Orexin A/Hypocretin-1 Antibody

Name: Orexin A/Hypocretin-1 Antibody
Brand: Novus Biologicals
SKU: NB100-65204
Price: 399 USD

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Immunohistochemistry-Paraffin: Orexin A/Hypocretin-1 Antibody [NB100-65204] - Staining of paraffin embedded human hypothalamus with Sheep anti Human Orexin A.

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	ELISA, IHC
Clonality	Polyclonal
Host	Sheep
Conjugate	Unconjugated
Concentration	5.0 mg/ml

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Orexin A/Hypocretin-1 Antibody Summary

Immunogen	Synthetic peptide, PLPDCCRQKTCSC, corresponding to amino acids 2-14 of human orexin A conjugated to KLH
Epitope	Peptide sequence: PLPDCCRQKTCSC
Localization	Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
Specificity	NB100-65204 is specific for human orexin A.
Isotype	IgG
Clonality	Polyclonal
Host	Sheep
Gene	HCRT
Purity	Affinity purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

ELISA 1:200-1:800
Immunohistochemistry 1:10-1:500
Immunohistochemistry-Frozen 1:10-1:500
Immunohistochemistry-Paraffin 5-10 ug/ml

Reactivity Notes

Based on sequence similarity, is expected to react with:Rhesus Monkey, Rat, Rabbit, Pig, Mouse, Horse, Dog, Chimpanzee, Bovine

Packaging, Storage & Formulations

Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer	PBS
Preservative	0.09% Sodium Azide
Concentration	5.0 mg/ml
Purity	Affinity purified

Alternate Names for Orexin A/Hypocretin-1 Antibody

HCRT
Hcrt1
hypocretin (orexin) neuropeptide precursor
Hypocretin1
Hypocretin-1
NRCLP1
Orexin A
orexin
OXHcrt
PPORX
PPOXHypocretin

Background

Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B(hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Orexin
A/Hypocretin-1 Antibo

NB100-65204

Species: Hu

Applications: ELISA, IHC

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Secondary Antibodies

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Bioinformatics

Gene Symbol	HCRT
Entrez	3060(Human)
Uniprot	O43612() O43612()

Popular Products	Company Information	Support	Stay Connected
Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Help Finding Antibodies Protocols

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Orexin A/Hypocretin-1 Antibody

Species Glossary

Images

Product Details

Order Details

Orexin A/Hypocretin-1 Antibody Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Alternate Names for Orexin A/Hypocretin-1 Antibody

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Orexin A/Hypocretin-1 Antibody (NB100-65204) (0)

Reviews for Orexin A/Hypocretin-1 Antibody (NB100-65204) (0)

Product General Protocols

FAQs for Orexin A/Hypocretin-1 Antibody (NB100-65204) (0)

Secondary Antibodies

Isotype Controls

Additional Orexin A/Hypocretin-1 Products

Research Areas for Orexin A/Hypocretin-1 Antibody (NB100-65204)

Blogs on Orexin A/Hypocretin-1

Customers Who Bought This Also Bought

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