Orthogonal Strategies: Western Blot: MxA/Mx1 Antibody [NBP1-83120] - Analysis in human cell lines SK-MEL-30 and U-251MG using anti-MX1 antibody. Corresponding MX1 RNA-seq data are presented for the same cell ...read more
Western Blot: MxA/Mx1 Antibody [NBP1-83120] - Analysis in human cell line SK-MEL-30 and human cell line A-549.
Immunohistochemistry-Paraffin: MxA/Mx1 Antibody [NBP1-83120] - Staining of human tonsil shows moderate to strong cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: MxA/Mx1 Antibody [NBP1-83120] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: MxA/Mx1 Antibody [NBP1-83120] - Staining of human skeletal muscle shows no cytoplasmic positivity in striated muscle fibers as expected.
Immunohistochemistry-Paraffin: MxA/Mx1 Antibody [NBP1-83120] - Staining of human small intestine shows strong cytoplasmic positivity in glandular as well as lymphoid cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: IEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MX1
Purity
Immunogen affinity purified
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Human reactivity reported in scientific literature (PMID: 25878567).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for MxA/Mx1 Antibody
human interferon-regulated resistance GTP-binding protein MXA10IFI-78Khomolog of murine (interferon-inducibleprotein p78)
IFI78
IFI-78K
Mx1
MxA
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78(mouse)
Background
In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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