Recombinant Human IFN-gamma Protein

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2). Mature human IFN-gamma exists as a non-covalently linked homodimer of 20-25 kDa variably glycosylated subunits (3). It shares 90% amino acid (aa) sequence identity with rhesus IFN-gamma , 59%‑64% with bovine, canine, equine, feline, and porcine IFN‑ gamma , and 37%‑43% with cotton rat, mouse, and rat IFN-gamma . IFN-gamma dimers bind to IFN-gamma RI ( alpha subunits) which then interact with IFN-gamma RII ( beta  subunits) to form the functional receptor complex of two alpha and two beta  subunits. Inclusion of IFN-gamma RII increases the binding affinity for ligand and the efficiency of signal transduction (4, 5). IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells (6). It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, up‑regulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects (6, 7). In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation (8, 9). The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis (7).

We have publications tested in 8 confirmed species: Human, Mouse, Rat, Hamster, N/A, Porcine, Primate - Chlorocebus pygerythrus (Vervet Monkey), Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque).

We have publications tested in 12 applications: Binding Assay, Bioassay, Cell Culture, Differentiation, ELISA (Capture), ELISA (Standard), ELISA Standard, In Vivo, Luminex (Detection), Reference Standard, Stimulation, Western Blot.

Showing Publications 1 - 10 of 455. Show All 455 Publications. Collapse Publications.

Publications using 285-IF	Applications	Species
Wang, P;Zhang, Y;Li, Z;Zhou, S;Tang, Q;Wang, Z;Xiao, R;Feng, M;Wu, L;Liang, D; Mesenchymal Stem Cells Derived from Human Urine-Derived iPSCs Exhibit Low Immunogenicity and Reduced Immunomodulatory Profile International journal of molecular sciences 2024-09-27 [PMID: 39408724] (Bioassay, Human)	Bioassay	Human
Schrijver, B;Göpfert, J;La Distia Nora, R;Putera, I;Nagtzaam, NMAN;Smits Te Nijenhuis, MAW;van Rijswijk, ALCT;Ten Berge, JCEM;van Laar, JAM;van Hagen, PM;Dik, WA; Increased serum interferon activity in sarcoidosis compared to that in tuberculosis: Implication for diagnosis? Heliyon 2024-09-30 [PMID: 39309852] (Luminex (Detection), Human)	Luminex (Detection)	Human
Li, Y;Li, TY;Qiao, Q;Zhang, MT;Tong, MX;Xu, LF;Zhang, ZB; Polymeric immunoglobulin receptor promotes Th2 immune response in the liver by increasing cholangiocytes derived IL-33: a diagnostic and therapeutic biomarker of biliary atresia EBioMedicine 2024-09-16 [PMID: 39288533] (Cell Culture, Human)	Cell Culture	Human
Lee, H;Xie, T;Kang, B;Yu, X;Schaffter, SW;Schulman, R; Plug-and-play protein biosensors using aptamer-regulated in vitro transcription Nature communications 2024-09-12 [PMID: 39266511] (Bioassay, Human)	Bioassay	Human
Arias, AA;Neehus, AL;Ogishi, M;Meynier, V;Krebs, A;Lazarov, T;Lee, AM;Arango-Franco, CA;Yang, R;Orrego, J;Corcini Berndt, M;Rojas, J;Li, H;Rinchai, D;Erazo-Borrás, L;Han, JE;Pillay, B;Ponsin, K;Chaldebas, M;Philippot, Q;Bohlen, J;Rosain, J;Le Voyer, T;Janotte, T;Amarajeeva, K;Soudée, C;Brollo, M;Wiegmann, K;Marquant, Q;Seeleuthner, Y;Lee, D;Lainé, C;Kloos, D;Bailey, R;Bastard, P;Keating, N;Rapaport, F;Khan, T;Moncada-Vélez, M;Carmona, MC;Obando, C;Alvarez, J;Cataño, JC;Martínez-Rosado, LL;Sanchez, JP;Tejada-Giraldo, M;L'Honneur, AS;Agudelo, ML;Perez-Zapata, LJ;Arboleda, DM;Alzate, JF;Cabarcas, F;Zuluaga, A;Pelham, SJ;Ensser, A;Schmidt, M;Velásquez-Lopera, MM;Jouanguy, E;Puel, A;Krönke, M;Ghirardello, S;Borghesi, A;Pahari, S;Boisson, B;Pittaluga, S;Ma, CS;Emile, JF;Notarangelo, LD;Tangye, SG;Marr, N;Lachmann, N;Salvator, H;Schlesinger, LS;Zhang, P;Glickman, MS;Nathan, CF;Geissmann, F;Abel, L;Franco, JL;Bustamante, J;Casanova, JL;Boisson-Dupuis, S; Tuberculosis in otherwise healthy adults with inherited TNF deficiency Nature 2024-08-28 [PMID: 39198650] (Bioassay, Human)	Bioassay	Human
Qian, B;Lu, R;Mao, S;Chen, Y;Yang, M;Zhang, W;Zhang, M;Zhu, D;Liu, Z;Zen, K;Li, L; Podocyte SIRP? reduction aggravates lupus nephritis via promoting T cell inflammatory responses Cell reports 2024-05-16 [PMID: 38758648] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Jeong, H;Koh, J;Kim, S;Song, SG;Lee, SH;Jeon, Y;Lee, CH;Keam, B;Lee, SH;Chung, DH;Jeon, YK; Epithelial-mesenchymal transition induced by tumor cell-intrinsic PD-L1 signaling predicts a poor response to immune checkpoint inhibitors in PD-L1-high lung cancer British journal of cancer 2024-05-10 [PMID: 38729997] (Bioassay, Human)	Bioassay	Human
Prelli Bozzo, C;Laliberté, A;De Luna, A;Pastorio, C;Regensburger, K;Krebs, S;Graf, A;Blum, H;Volcic, M;Sparrer, KMJ;Kirchhoff, F; Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef Nature communications 2024-05-07 [PMID: 38714682] (Bioassay, Human)	Bioassay	Human
Huang, T;Leung, B;Huang, Y;Price, L;Gui, J;Lau, BW; A murine model to evaluate immunotherapy effectiveness for human Fanconi anemia-mutated acute myeloid leukemia PloS one 2024-01-30 [PMID: 38289944] (Bioassay, Human)	Bioassay	Human
Manara, MC;Manferdini, C;Cristalli, C;Carrabotta, M;Santi, S;De Feo, A;Caldoni, G;Pasello, M;Landuzzi, L;Lollini, PL;Salamanna, F;Dominici, S;Fiori, V;Magnani, M;Lisignoli, G;Scotlandi, K; Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages Cancer immunology research 2023-12-04 [PMID: 38051221] (Bioassay, Human)	Bioassay	Human
Liu, J;Deng, Y;Wang, A;Liu, B;Zhou, X;Yin, T;Wang, Y;Tang, T;Qiu, Y;Chen, J;Yang, J; Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface Cell death & disease 2023-11-28 [PMID: 38012139] (Bioassay, Human)	Bioassay	Human
Katagata, M;Okayama, H;Nakajima, S;Saito, K;Sato, T;Sakuma, M;Fukai, S;Endo, E;Sakamoto, W;Saito, M;Saze, Z;Momma, T;Mimura, K;Kono, K; TIM-3 Expression and M2 Polarization of Macrophages in the TGF?-Activated Tumor Microenvironment in Colorectal Cancer Cancers 2023-10-11 [PMID: 37894310] (Cell Culture)	Cell Culture
Li, WW;Fan, XX;Zhu, ZX;Cao, XJ;Zhu, ZY;Pei, DS;Wang, YZ;Zhang, JY;Wang, YY;Zheng, HX; Tyrosine phosphorylation of IRF3 by BLK facilitates its sufficient activation and innate antiviral response PLoS pathogens 2023-10-01 [PMID: 37871014] (Bioassay, Human)	Bioassay	Human
Carter, R;Alanazi, F;Sharp, A;Roman, J;Luchini, A;Liotta, L;Paige, M;Brown, AM;Haymond, A; Identification of the Functional PD-L1 Interface Region Responsible for PD-1 Binding and Initiation of PD-1 Signaling The Journal of biological chemistry 2023-10-17 [PMID: 37858677] (Bioassay, Human)	Bioassay	Human
Gadde, M;Mehrabi-Dehdezi, M;Debeb, BG;Woodward, WA;Rylander, MN; Influence of Macrophages on Vascular Invasion of Inflammatory Breast Cancer Emboli Measured Using an In Vitro Microfluidic Multi-Cellular Platform Cancers 2023-10-08 [PMID: 37835577] (Bioassay, Human)	Bioassay	Human
Amarasinghe, HE;Zhang, P;Whalley, JP;Allcock, A;Migliorini, G;Brown, AC;Scozzafava, G;Knight, JC; Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance BMC genomics 2023-10-07 [PMID: 37805492] (Bioassay, Human)	Bioassay	Human
Pasquesi, GIM;Allen, H;Ivancevic, A;Barbachano-Guerrero, A;Joyner, O;Guo, K;Simpson, DM;Gapin, K;Horton, I;Nguyen, L;Yang, Q;Warren, CJ;Florea, LD;Bitler, BG;Santiago, ML;Sawyer, SL;Chuong, EB; Regulation of human interferon signaling by transposon exonization bioRxiv : the preprint server for biology 2023-09-15 [PMID: 37745311] (Bioassay, Human)	Bioassay	Human
Bass, AR;Egan, MS;Alexander-Floyd, J;Lopes Fischer, N;Doerner, J;Shin, S; Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation mBio 2023-09-22 [PMID: 37737612] (Bioassay, Human)	Bioassay	Human
Smith, AA;Nip, Y;Bennett, SR;Hamm, DC;Lemmers, RJLF;van der Vliet, PJ;Setty, M;van der Maarel, SM;Tapscott, SJ; DUX4 expression in cancer induces a metastable early embryonic totipotent program Cell reports 2023-09-08 [PMID: 37691147] (Bioassay, Human)	Bioassay	Human
Lee, H;Xie, T;Yu, X;Schaffter, SW;Schulman, R; Plug-and-play protein biosensors using aptamer-regulated in vitro transcription bioRxiv : the preprint server for biology 2023-08-14 [PMID: 37645783] (Bioassay, Human)	Bioassay	Human
Mhaidly, N;Journe, F;Najem, A;Stock, L;Trelcat, A;Dequanter, D;Saussez, S;Descamps, G; Macrophage Profiling in Head and Neck Cancer to Improve Patient Prognosis and Assessment of Cancer Cell-Macrophage Interactions Using Three-Dimensional Coculture Models International journal of molecular sciences 2023-08-15 [PMID: 37628994] (Bioassay, Human)	Bioassay	Human
Lu, J;Zhang, Q;Mo, L;Chen, W;Mao, L; Comprehensive analysis of E47?like factors and verification of ELF4 in clear cell renal cell carcinoma Oncology letters 2023-09-01 [PMID: 37600328] (Bioassay, Human)	Bioassay	Human
Converti, A;Bianchi, MS;Martinez, MD;Montaner, AD;Lux-Lantos, V;Bonaventura, MM; IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation Physiological reports 2023-08-01 [PMID: 37568265] (Bioassay, Mouse)	Bioassay	Mouse
Guirguis, AA;Ofir-Rosenfeld, Y;Knezevic, K;Blackaby, W;Hardick, D;Chan, YC;Motazedian, A;Gillespie, A;Vassiliadis, D;Lam, EY;Tran, K;Andrews, B;Harbour, ME;Vasiliauskaite, L;Saunders, CJ;Tsagkogeorga, G;Azevedo, A;Obacz, J;Pilka, ES;Carkill, M;MacPherson, L;Wainwright, EN;Liddicoat, B;Blyth, BJ;Albertella, MR;Rausch, O;Dawson, MA; Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances anti-tumour immunity Cancer discovery 2023-08-07 [PMID: 37548590] (Bioassay, Human)	Bioassay	Human
Yoon, J;Lee, SK;Park, A;Lee, J;Jung, I;Song, KB;Choi, EJ;Kim, S;Yu, J; Exosome from IFN-gamma -Primed Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Improved Skin Inflammation and Barrier Function International journal of molecular sciences 2023-07-19 [PMID: 37511392] (Cell Culture, Human)	Cell Culture	Human
Fusi, G;Constantinides, M;Fissoun, C;Pichard, L;Pers, YM;Ferreira-Lopez, R;Pantesco, V;Poulet, C;Malaise, O;De Seny, D;Lemaitre, JM;Jorgensen, C;Brondello, JM; Senescence-Driven Inflammatory and Trophic Microenvironment Imprints Mesenchymal Stromal/Stem Cells in Osteoarthritic Patients Biomedicines 2023-07-14 [PMID: 37509633] (Bioassay, Human)	Bioassay	Human
Xu, D;Jiang, W;Wu, L;Gaudet, RG;Park, ES;Su, M;Cheppali, SK;Cheemarla, NR;Kumar, P;Uchil, PD;Grover, JR;Foxman, EF;Brown, CM;Stansfeld, PJ;Bewersdorf, J;Mothes, W;Karatekin, E;Wilen, CB;MacMicking, JD; PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection Nature 2023-07-12 [PMID: 37438530] (Bioassay, Human)	Bioassay	Human
Doshi, A;Erickson, P;Teryek, M;Parekkadan, B; Dynamics of Ex Vivo Mesenchymal Stromal Cell Potency under Continuous Perfusion International journal of molecular sciences 2023-05-31 [PMID: 37298556] (Bioassay, Human)	Bioassay	Human
Soldati, S;B�r, A;Vladymyrov, M;Glavin, D;McGrath, JL;Gosselet, F;Nishihara, H;Goelz, S;Engelhardt, B; High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro Journal of neuroinflammation 2023-05-23 [PMID: 37221552] (Bioassay, Human)	Bioassay	Human
Zheng, X;Sarode, P;Weigert, A;Turkowski, K;Chelladurai, P;G�nther, S;Kuenne, C;Winter, H;Stenzinger, A;Reu, S;Grimminger, F;Stiewe, T;Seeger, W;Pullamsetti, SS;Savai, R; The HDAC2-SP1 axis orchestrates pro-tumor macrophage polarization Cancer research 2023-05-19 [PMID: 37205635] (Bioassay, Human)	Bioassay	Human
CY Lin, KY Huang, SH Kao, MS Lin, CC Lin, SC Yang, WC Chung, YH Chang, RJ Chein, PC Yang Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response Science Advances, 2023-04-07;9(14):eade9944. 2023-04-07 [PMID: 37027467] (Bioassay, Human)	Bioassay	Human
D Avancini, A Testori, L Fresolone, G Andolfi, M Vuono, V Martinelli, FR Santoni de, S Gregori Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells Cell Reports, 2023-03-03;42(3):112193. 2023-03-03 [PMID: 36870061] (Reference Standard, Human)	Reference Standard	Human
H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, C Lucas, I Cohen, S Coffey, N Lele, L Greta, K Raddassi, O Chaudhary, A Unterman, B Emu, SH Kleinstein, RR Montgomery, A Iwasaki, CS Dela Cruz, N Kaminski, AC Shaw, DA Hafler, TS Sumida PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection Cell Reports, 2023-01-02;0(0):111895. 2023-01-02 [PMID: 36596303] (Cell Culture, Human)	Cell Culture	Human
E Turner, L Chen, JG Foulke, Z Gu, F Tian CRISPR/Cas9 Edited RAS & MEK Mutant Cells Acquire BRAF and MEK Inhibitor Resistance with MEK1 Q56P Restoring Sensitivity to MEK/BRAF Inhibitor Combo and KRAS G13D Gaining Sensitivity to Immunotherapy Cancers, 2022-11-05;14(21):. 2022-11-05 [PMID: 36358868] (Bioassay, Human)	Bioassay	Human
S Hayashi, CK Muraleedha, M Oku, S Tomar, SP Hogan, M Quiros, CA Parkos, A Nusrat Intestinal epithelial BLT1 promotes mucosal repair JCI Insight, 2022-12-08;0(0):. 2022-12-08 [PMID: 36301666] (Bioassay, Human)	Bioassay	Human
P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease Cell Reports, 2022-09-27;40(13):111439. 2022-09-27 [PMID: 36170836] (Bioassay, Human)	Bioassay	Human
S Mitra, R Gera, J Sundheimer, M Lemee, LU Wahlberg, B Linderoth, M Eriksdotte, H Behbahani Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimer's Disease Therapy International Journal of Molecular Sciences, 2022-08-12;23(16):. 2022-08-12 [PMID: 36012296] (Bioassay, Human)	Bioassay	Human
T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119. 2022-08-22 [PMID: 35994674] (Cell Culture, Human)	Cell Culture	Human
S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge STUB1 is an intracellular checkpoint for interferon gamma sensing Scientific Reports, 2022-08-18;12(1):14087. 2022-08-18 [PMID: 35982220] (Bioassay, Human)	Bioassay	Human
S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii Nature Communications, 2022-08-08;13(1):4605. 2022-08-08 [PMID: 35941154] (Bioassay, Human)	Bioassay	Human
Z Zhang, Y Xun, S Rong, L Yan, JA SoRelle, X Li, M Tang, K Keller, S Ludwig, EMY Moresco, B Beutler Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity Nature Communications, 2022-07-16;13(1):4136. 2022-07-16 [PMID: 35842425] (Bioassay, Human)	Bioassay	Human
S Padmanabha, B Gaire, Y Zou, MM Uddin, I Vancurova IFNgamma-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signaling Cellular Signalling, 2022-07-09;97(0):110400. 2022-07-09 [PMID: 35820543] (Bioassay, Human)	Bioassay	Human
XJ Mi, JK Kim, S Lee, SK Moon, YJ Kim, H Kim In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals Journal of ethnopharmacology, 2022-07-07;296(0):115523. 2022-07-07 [PMID: 35809756] (Bioassay, Human)	Bioassay	Human
MD Gundersen, KB Larsen, KM Johnsen, R Goll, J Florholmen, G Haraldsen Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis Scientific Reports, 2022-07-07;12(1):11550. 2022-07-07 [PMID: 35798804] (Bioassay, Human)	Bioassay	Human
CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells Journal of advanced research, 2021-11-19;39(0):73-88. 2021-11-19 [PMID: 35777918] (Bioassay, Human)	Bioassay	Human
Y Yoshinaga, T Soma, S Azuma, K Maruyama, Y Hashikawa, T Katayama, Y Sasamoto, H Takayanagi, N Hosen, T Shiina, K Ogasawara, R Hayashi, K Nishida Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets Stem Cell Reports, 2022-06-23;0(0):. 2022-06-23 [PMID: 35750044] (Bioassay, Human)	Bioassay	Human
E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, S Sinha, M Perry, GA Duncan, MA Scull Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium MBio, 2022-06-14;0(0):e0105522. 2022-06-14 [PMID: 35699372] (Bioassay, Human)	Bioassay	Human
S Hong, EY Kim, SE Lim, JH Kim, Y Sohn, HS Jung Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells International Journal of Molecular Sciences, 2022-04-18;23(8):. 2022-04-18 [PMID: 35457288] (Bioassay, Human)	Bioassay	Human
DY Zander, SS Burkart, S Wüst, VG Magalhães, M Binder Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death Cell Death & Disease, 2022-04-18;13(4):364. 2022-04-18 [PMID: 35436994] (Bioassay, Human)	Bioassay	Human
L Casciola-R, DR Thiemann, F Andrade, MI Trejo-Zamb, EK Leonard, JB Spangler, NE Skinner, J Bailey, S Yegnasubra, R Wang, AM Vaghasia, A Gupta, AL Cox, SC Ray, RM Linville, Z Guo, PC Searson, CE Machamer, S Desiderio, LM Sauer, O Laeyendeck, BT Garibaldi, L Gao, M Damarla, PM Hassoun, JE Hooper, CA Mecoli, L Christophe, L Gutierrez-, Q Yang, D Hines, WA Clarke, RE Rothman, A Pekosz, KZ Fenstermac, Z Wang, SL Zeger, A Rosen IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function JCI Insight, 2022-05-09;7(9):. 2022-05-09 [PMID: 35349483] (Bioassay, Human)	Bioassay	Human
P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells Cancers, 2022-03-11;14(6):. 2022-03-11 [PMID: 35326601] (Cell Culture, Human)	Cell Culture	Human
T Schmit, K Guo, JK Tripathi, Z Wang, B McGregor, M Klomp, G Ambigapath, R Mathur, J Hur, M Pichichero, J Kolls, MN Khan Interferon-gamma promotes monocyte-mediated lung injury during influenza infection Cell Reports, 2022-03-01;38(9):110456. 2022-03-01 [PMID: 35235782] (Bioassay, Human)	Bioassay	Human
A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response Cancer Immunology Research, 2022-04-01;0(0):. 2022-04-01 [PMID: 35181787] (Bioassay, Human)	Bioassay	Human
J Kim, H Jang, GJ Lee, Y Hur, J Keum, JK Jo, SE Yun, SJ Park, YJ Park, MJ Choi, KS Kim, J Kim A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-gamma-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells Cells, 2021-12-22;11(1):. 2021-12-22 [PMID: 35011581] (Cell Culture, Human)	Cell Culture	Human
PL Chi, CC Cheng, CC Hung, MT Wang, HY Liu, MW Ke, MC Shen, KC Lin, SH Kuo, PP Hsieh, SR Wann, WC Huang MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension International journal of biological sciences, 2022-01-01;18(1):331-348. 2022-01-01 [PMID: 34975336] (Bioassay, Human)	Bioassay	Human
SR Rosenbaum, M Tiago, S Caksa, C Capparelli, TJ Purwin, G Kumar, M Glasheen, D Pomante, D Kotas, I Chervoneva, AE Aplin SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects Cell Reports, 2021-12-07;37(10):110085. 2021-12-07 [PMID: 34879275] (Bioassay, Human)	Bioassay	Human
A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets Cell Reports, 2021-11-23;37(8):110037. 2021-11-23 [PMID: 34818536] (Bioassay, Human)	Bioassay	Human
Y Song, G Hou, J Diep, YS Ooi, NS Akopyants, SM Beverley, JE Carette, HB Greenberg, S Ding Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation Nucleic Acids Research, 2021-12-16;0(0):. 2021-12-16 [PMID: 34791430] (Bioassay, Human)	Bioassay	Human
E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, SH Nam, JW Lee TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment Cell Reports, 2021-11-16;37(7):110018. 2021-11-16 [PMID: 34788612] (Bioassay, Human)	Bioassay	Human
YH Liang, KH Chen, JH Tsai, YM Cheng, CC Lee, CH Kao, KY Chan, YT Chen, WL Hsu, KH Yeh Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells Journal of Biomedical Science, 2021-11-10;28(1):75. 2021-11-10 [PMID: 34758826] (Bioassay, Human)	Bioassay	Human
C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling The Journal of Biological Chemistry, 2021-11-03;0(0):101380. 2021-11-03 [PMID: 34740611] (Bioassay, Human)	Bioassay	Human
S Wüst, P Schad, S Burkart, M Binder Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses Cells, 2021-09-30;10(10):. 2021-09-30 [PMID: 34685580] (Stimulation, Human)	Stimulation	Human
HJ Lee, HD Kim, CH Jo, EY Bok, SB Kim, SL Lee, M Jang, SG Bae, SH Yun, SJ Kim, GJ Rho, WJ Lee IFN-gamma Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application BioMed Research International, 2021-09-04;2021(0):4604856. 2021-09-04 [PMID: 34527737] (Bioassay, Porcine)	Bioassay	Porcine
S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris JCI Insight, 2021-10-22;0(0):. 2021-10-22 [PMID: 34491907] (Bioassay, Human)	Bioassay	Human
N Abu-Shahba, M Mahmoud, AM El-Erian, MI Husseiny, G Nour-Eldee, I Helwa, K Amr, M ElHefnawi, AI Othman, SA Ibrahim, O Azmy Impact of Type 2 Diabetes Mellitus on the Immunoregulatory Characteristics of Adipose Tissue-Derived Mesenchymal Stem Cells The international journal of biochemistry & cell biology, 2021-08-26;0(0):106072. 2021-08-26 [PMID: 34455058] (Bioassay, Human)	Bioassay	Human
XY Zhu, N Klomjit, SM Conley, MM Ostlie, KL Jordan, A Lerman, LO Lerman Impaired immunomodulatory capacity in adipose tissue-derived mesenchymal stem/stromal cells isolated from obese patients Journal of Cellular and Molecular Medicine, 2021-08-21;0(0):. 2021-08-21 [PMID: 34418300] (Bioassay, Human)	Bioassay	Human
S Nakajima, K Mimura, T Matsumoto, AK Thar Min, M Ito, H Nakano, P Neupane, Y Kanke, H Okayama, M Saito, T Momma, Y Watanabe, H Hanayama, S Hayase, Z Saze, K Kono The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells Scientific Reports, 2021-08-19;11(1):16891. 2021-08-19 [PMID: 34413454] (Bioassay, Human)	Bioassay	Human
S Azari, LJ Johnson, A Webb, SM Kozlowski, X Zhang, K Rood, A Amer, S Seveau Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors MBio, 2021-08-17;12(4):e0184921. 2021-08-17 [PMID: 34399615] (Bioassay, Human)	Bioassay	Human
C Prelli Boz, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, S Heller, CM Stürzel, D Kmiec, C Conzelmann, J Müller, F Zech, E Braun, R Gro beta , L Wettstein, T Weil, J Wei beta , F Diofano, AA Rodríguez, S Wiese, D Sauter, J Münch, C Goffinet, A Catanese, M Schön, TM Boeckers, S Stenger, K Sato, S Just, A Kleger, KMJ Sparrer, F Kirchhoff IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro Nature Communications, 2021-07-28;12(1):4584. 2021-07-28 [PMID: 34321474] (Bioassay, Human)	Bioassay	Human
S Luostarine, M Hämäläinen, N Hatano, K Muraki, E Moilanen The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells Pulmonary pharmacology & therapeutics, 2021-07-21;70(0):102059. 2021-07-21 [PMID: 34302984] (Bioassay, Human)	Bioassay	Human
D Lobato-Már, J Xu, GÖ Güler, A Ojiakor, M Pilhofer, S Mostowy Mechanistic insight into bacterial entrapment by septin cage reconstitution Nature Communications, 2021-07-23;12(1):4511. 2021-07-23 [PMID: 34301939] (Bioassay, Human)	Bioassay	Human
R Luna-Yolba, J Marmoiton, V Gigo, X Marechal, E Boet, A Sahal, N Alet, I Abramovich, E Gottlieb, V Visentin, MR Paillasse, JE Sarry Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells Cancers, 2021-07-13;13(14):. 2021-07-13 [PMID: 34298712] (Bioassay, Human)	Bioassay	Human
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JS Aguilar Dí, HL Glenn, M Knappenber, CR Borges Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells Journal of Cancer, 2021-06-16;12(16):4993-5004. 2021-06-16 [PMID: 34234868] (ELISA (Capture), Human)	ELISA (Capture)	Human
H Lee, DH Lee, JH Oh, JH Chung Skullcapflavone II Suppresses TNF-alpha/IFN-gamma-Induced TARC, MDC, and CTSS Production in HaCaT Cells International Journal of Molecular Sciences, 2021-06-16;22(12):. 2021-06-16 [PMID: 34208434] (Bioassay, Human)	Bioassay	Human
AC Tecalco-Cr, M Macías-Sil, JO Ramírez-Ja, B Méndez-Amb Identification of genes modulated by interferon gamma in breast cancer cells Biochemistry and Biophysics Reports, 2021-06-16;27(0):101053. 2021-06-16 [PMID: 34189281] (Cell Culture, Human)	Cell Culture	Human
SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer Nature Communications, 2021-06-03;12(1):3299. 2021-06-03 [PMID: 34083537] (Bioassay, Human)	Bioassay	Human
MC Suárez-Arr, A Méndez-Ten, V Pérez-Kold, EM Fuentes-Pa Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity Cancers, 2021-05-07;13(9):. 2021-05-07 [PMID: 34067089] (Bioassay, Human)	Bioassay	Human
T Seime, AC Akbulut, ML Liljeqvist, A Siika, H Jin, G Winski, RH van Gorp, E Karlöf, M Lengquist, AJ Buckler, M Kronqvist, OJ Waring, JHN Lindeman, EAL Biessen, L Maegdefess, A Razuvaev, LJ Schurgers, U Hedin, L Matic Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification Cells, 2021-05-21;10(6):. 2021-05-21 [PMID: 34063989] (Bioassay, Human)	Bioassay	Human
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BY Wang, YY Ye, C Qian, HB Zhang, HX Mao, LP Yao, X Sun, GH Lu, SZ Zhang Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease Neural regeneration research, 2021-12-01;16(12):2521-2527. 2021-12-01 [PMID: 33907043] (Bioassay, Human)	Bioassay	Human
Bsat M, Mehta H, Rubio M, Sarfati M The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages. Curr Protoc, 2021-03-01;1(3):e74. 2021-03-01 [PMID: 33705607] (Bioassay, Human)	Bioassay	Human
L Jerby-Arno, C Neftel, ME Shore, HR Weisman, ND Mathewson, MJ McBride, B Haas, B Izar, A Volorio, G Boulay, L Cironi, AR Richman, LC Broye, JM Gurski, CC Luo, R Mylvaganam, L Nguyen, S Mei, JC Melms, C Georgescu, O Cohen, JE Buendia-Bu, A Segerstolp, M Sud, MS Cuoco, D Labes, S Gritsch, DR Zollinger, N Ortogero, JM Beechem, G Petur Niel, I Chebib, T Nguyen-Ngo, M Montemurro, GM Cote, E Choy, I Letovanec, S Cherix, N Wagle, PK Sorger, AB Haynes, JT Mullen, I Stamenkovi, MN Rivera, C Kadoch, KW Wucherpfen, O Rozenblatt, ML Suvà, N Riggi, A Regev Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma Nature Medicine, 2021-01-25;0(0):. 2021-01-25 [PMID: 33495604] (Bioassay, Human)	Bioassay	Human
H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 2021-01-21;11(1):1949. 2021-01-21 [PMID: 33479269] (Bioassay, Human)	Bioassay	Human
TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes EBioMedicine, 2021-01-12;63(0):103175. 2021-01-12 [PMID: 33450518] (Bioassay, Human)	Bioassay	Human
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ZZ Bai, HY Li, CH Li, CL Sheng, XN Zhao M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-&kappaB Signaling Pathway Nanoscale research letters, 2020-12-02;15(1):221. 2020-12-02 [PMID: 33263825] (Human)		Human
X Li, G Yin, W Ji, J Liu, Y Zhang, J Wang, X Zhu, L Zhu, D Dai, W Ma, W Xu 18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model Onco Targets Ther, 2020-11-13;13(0):11659-11668. 2020-11-13 [PMID: 33223839] (Cell Culture, Human)	Cell Culture	Human
V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells Nat Commun, 2020-10-14;11(1):5163. 2020-10-14 [PMID: 33057020] (Bioassay, Human)	Bioassay	Human
J Bhushan, JB Radke, YC Perng, M Mcallaster, DJ Lenschow, HW Virgin, LD Sibley ISG15 Connects Autophagy and IFN-&gamma-Dependent Control of Toxoplasma gondii Infection in Human Cells MBio, 2020-10-06;11(5):. 2020-10-06 [PMID: 33024031] (Cell Culture, Human)	Cell Culture	Human
EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation PLoS ONE, 2020-10-06;15(10):e0240319. 2020-10-06 [PMID: 33021986] (Cell Culture, Human)	Cell Culture	Human
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B Cioni, A Zaalberg, JR van Beijnu, MHM Melis, J van Burgst, MJ Muraro, E Hooijberg, D Peters, I Hofland, Y Lubeck, J de Jong, J Sanders, J Vivié, HG van der Po, JP de Boer, AW Griffioen, W Zwart, AM Bergman Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion Nat Commun, 2020-09-09;11(1):4498. 2020-09-09 [PMID: 32908142] (Bioassay, Human)	Bioassay	Human
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S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia Cells, 2020-08-31;9(9):. 2020-08-31 [PMID: 32878300] (Bioassay, Human)	Bioassay	Human
F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2 Res Sq, 2020-09-15;0(0):. 2020-09-15 [PMID: 32839764] (Bioassay, Human)	Bioassay	Human
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A Gustafsson, Z Prgomet, S Jankovskaj, T Ruzgas, J Engblom, L Ohlsson, A Gjörloff W Effect of IFN-gamma on the kynurenine/tryptophan ratio in monolayer-cultured keratinocytes and a 3D reconstructed human epidermis model J. Dermatol. Sci., 2020-07-17;0(0):. 2020-07-17 [PMID: 32782183] (Bioassay, Human)	Bioassay	Human
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NC Leite, E Sintov, TB Meissner, MA Brehm, DL Greiner, DM Harlan, DA Melton Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells Cell Rep, 2020-07-14;32(2):107894. 2020-07-14 [PMID: 32668238] (Bioassay, Human)	Bioassay	Human
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A Ruiz, S Guzmán-Bel, LE Carreto-Bi, Y Gonzalez, E Juárez DNA from virulent M. tuberculosis induces TNF-? production and autophagy in M1 polarized macrophages Microb. Pathog., 2019-05-02;0(0):. 2019-05-02 [PMID: 31054870] (Bioassay, Human)	Bioassay	Human
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JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis J Immunol Res, 2019-02-06;2019(0):1529189. 2019-02-06 [PMID: 30882002] (Bioassay, Human)	Bioassay	Human
M Ashizawa, H Okayama, T Ishigame, AK Thar Min, K Saito, D Ujiie, Y Murakami, T Kikuchi, Y Nakayama, M Noda, T Tada, H Endo, S Fujita, W Sakamoto, M Saito, Z Saze, T Momma, S Ohki, K Mimura, K Kono microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L1 Mol. Cancer Res., 2019-03-14;0(0):. 2019-03-14 [PMID: 30872332] (Bioassay, Human)	Bioassay	Human
N Roper, S Gao, TK Maity, AR Banday, X Zhang, A Venugopala, CM Cultraro, R Patidar, S Sindiri, AL Brown, A Goncearenc, AR Panchenko, R Biswas, A Thomas, A Rajan, CA Carter, DE Kleiner, SM Hewitt, J Khan, L Prokunina-, U Guha APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors Cell Rep, 2019-03-05;26(10):2651-2666.e6. 2019-03-05 [PMID: 30840888] (Bioassay, Human)	Bioassay	Human
M Kita, Y Ano, A Inoue, J Aoki Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells Sci Rep, 2019-02-28;9(1):3135. 2019-02-28 [PMID: 30816271] (Bioassay, Human)	Bioassay	Human
F Feng, J Zhao, P Li, R Li, L Chen, C Sun Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells Viruses, 2019-02-13;11(2):. 2019-02-13 [PMID: 30781810] (Bioassay, Human)	Bioassay	Human
K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye Int J Mol Sci, 2019-02-16;20(4):. 2019-02-16 [PMID: 30781494] (Bioassay, Human)	Bioassay	Human
BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis Sci Rep, 2019-02-04;9(1):1149. 2019-02-04 [PMID: 30718719] (Bioassay, Human)	Bioassay	Human
T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS Cancer Res., 2019-02-01;0(0):. 2019-02-01 [PMID: 30709930] (Bioassay, Human)	Bioassay	Human
K Gettler, M Giri, E Kenigsberg, J Martin, LS Chuang, NY Hsu, LA Denson, JS Hyams, A Griffiths, JD Noe, WV Crandall, DR Mack, R Kellermaye, C Abraham, G Hoffman, S Kugathasan, JH Cho Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets Genes Immun., 2019-01-29;0(0):. 2019-01-29 [PMID: 30692607] (Bioassay, Human)	Bioassay	Human
WY Lei, SC Hsiung, SH Wen, CH Hsieh, CL Chen, CG Wallace, CC Chang, SK Liao Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines J Immunol Res, 2018-12-16;2018(0):8363265. 2018-12-16 [PMID: 30648121] (Bioassay, Human)	Bioassay	Human
SE Jin, H Ha, HK Shin, CS Seo Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes Molecules, 2019-01-11;24(2):. 2019-01-11 [PMID: 30642008] (Bioassay, Human)	Bioassay	Human
S Bai, T Chen, X Deng Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells Stem Cells Int, 2018-11-28;2018(0):6082956. 2018-11-28 [PMID: 30622567] (Bioassay, Human)	Bioassay	Human
ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, NM Savage, PJ Buckhaults, HC Morse, K Liu Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis Cell Rep, 2018-12-11;25(11):3036-3046.e6. 2018-12-11 [PMID: 30540937] (Bioassay, Human)	Bioassay	Human
E Cruz-Ramos, M Macías-Sil, A Sandoval-H, AC Tecalco-Cr Non-muscle myosin IIA is post-translationally modified by interferon-stimulated gene 15 in breast cancer cells Int. J. Biochem. Cell Biol., 2018-12-05;107(0):14-26. 2018-12-05 [PMID: 30529400] (Bioassay, Human)	Bioassay	Human
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M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence Cell. Physiol. Biochem., 2018-11-26;51(3):1103-1118. 2018-11-26 [PMID: 30476917] (Bioassay, Human)	Bioassay	Human
S Tomi?, N Ili?, V Kokol, A Gruden-Mov, D Mihajlovi?, M Beki?, L Sofroni?-M, M ?oli?, D Vu?evi? Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells Int J Nanomedicine, 2018-10-31;13(0):6941-6960. 2018-10-31 [PMID: 30464452] (Bioassay, Human)	Bioassay	Human
S Muntaka, Y Almuhanna, D Jackson, S Singh, A Afryie-Asa, M Cámara, L Martínez-P IFN-? and IL-17A differentially influence the response of human macrophages and neutrophils to Pseudomonas aeruginosa infection Infect. Immun., 2019-01-24;0(0):. 2019-01-24 [PMID: 30455194] (Bioassay, Human)	Bioassay	Human
DA Bejarano, MC Puertas, K Börner, J Martinez-P, B Müller, HG Kräusslich Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages Viruses, 2018-11-10;10(11):. 2018-11-10 [PMID: 30423802] (Bioassay, Human)	Bioassay	Human
K Vaeteewoot, R Kariya, P Pothipan, S Fujikawa, C Pairojkul, S Waraasawap, K Kuwahara, C Wongkham, S Wongkham, S Okada Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis Transl Oncol, 2018-11-09;12(2):217-225. 2018-11-09 [PMID: 30415063] (Bioassay, Human)	Bioassay	Human
HK Park, M Kim, M Sung, SE Lee, YJ Kim, YL Choi Status of programmed death-ligand 1 expression in sarcomas J Transl Med, 2018-11-06;16(1):303. 2018-11-06 [PMID: 30400799] (Bioassay, Human)	Bioassay	Human
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K Mulati, J Hamanishi, N Matsumura, K Chamoto, N Mise, K Abiko, T Baba, K Yamaguchi, N Horikawa, R Murakami, M Taki, K Budiman, X Zeng, Y Hosoe, M Azuma, I Konishi, M Mandai VISTA expressed in tumour cells regulates T cell function Br. J. Cancer, 2018-11-09;0(0):. 2018-11-09 [PMID: 30382166] (Bioassay, Human)	Bioassay	Human
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TJ Bussian, A Aziz, CF Meyer, BL Swenson, JM van Deurse, DJ Baker Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline Nature, 2018-09-19;0(0):. 2018-09-19 [PMID: 30232451] (Bioassay, Mouse)	Bioassay	Mouse
ED Anderson, I Sastalla, NJ Earland, M Mahnaz, IN Moore, F Otaizo-Car, TG Myers, CA Myles, SK Datta, IA Myles Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632 PLoS ONE, 2018-09-12;13(9):e0198862. 2018-09-12 [PMID: 30208113] (Bioassay, Human)	Bioassay	Human
M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-? Physiol Rep, 2018-08-01;6(16):e13831. 2018-08-01 [PMID: 30136410] (Bioassay, Human)	Bioassay	Human
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NM Plugis, N Weng, Q Zhao, BA Palanski, HT Maecker, A Habtezion, C Khosla Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin Proc. Natl. Acad. Sci. U.S.A., 2018-08-13;0(0):. 2018-08-13 [PMID: 30104382] (Bioassay, Human)	Bioassay	Human
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MA Terkawi, R Takano, K Kato Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes J Immunol Res, 2018-07-05;2018(0):6709424. 2018-07-05 [PMID: 30069491] (Bioassay, Human)	Bioassay	Human
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LCD Smyth, J Rustenhove, TI Park, P Schweder, D Jansson, PA Heppner, SJ O'Carroll, EW Mee, RLM Faull, M Curtis, M Dragunow Unique and shared inflammatory profiles of human brain endothelia and pericytes J Neuroinflammation, 2018-05-11;15(1):138. 2018-05-11 [PMID: 29751771] (Bioassay, Human)	Bioassay	Human
E Vorkapic, A Kunath, D Wågsäter Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms Mol Med Rep, 2018-04-27;0(0):. 2018-04-27 [PMID: 29749489] (Bioassay, Human)	Bioassay	Human
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RB Nahomi, S Sampathkum, AM Myers, L Elghazi, DG Smith, J Tang, CA Lee, TS Kern, RH Nagaraj, PE Fort The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2042-2053. 2018-04-01 [PMID: 29677366] (Bioassay, Human)	Bioassay	Human
C Lema, RY Reins, RL Redfern High-Mobility Group Box 1 in Dry Eye Inflammation Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1741-1750. 2018-04-01 [PMID: 29610858] (Bioassay, Human)	Bioassay	Human
S Sugita, K Makabe, Y Iwasaki, S Fujii, M Takahashi Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1719-1731. 2018-04-01 [PMID: 29610856] (Bioassay, Human)	Bioassay	Human
DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 2018-09-01;0(0):. 2018-09-01 [PMID: 29596569] (Bioassay, Human)	Bioassay	Human
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D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus Sci Rep, 2018-03-23;8(1):5126. 2018-03-23 [PMID: 29572460] (Bioassay, Human)	Bioassay	Human
F Huang, B Wang, J Zeng, S Sang, J Lei, Y Lu MicroRNA-374b inhibits liver cancer progression via down regulating programmed cell death-1 expression on cytokine-induced killer cells Oncol Lett, 2018-02-05;15(4):4797-4804. 2018-02-05 [PMID: 29552119] (Bioassay, Human)	Bioassay	Human
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MW Tang, B Malvar Fer, SP Newsom, JD van Buul, TRDJ Radstake, DL Baeten, PP Tak, KA Reedquist, S García Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes Rheumatology (Oxford), 2018-05-01;0(0):. 2018-05-01 [PMID: 29471421] (Differentiation, Differentiation, Human)	Differentiation, Differentiation	Human
N Singh, P Kansal, Z Ahmad, N Baid, H Kushwaha, N Khatri, A Kumar Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy is dependent on the HMOX1 (heme oxygenase 1)-mediated increase in the intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis Autophagy, 2018-05-10;0(0):1-57. 2018-05-10 [PMID: 29457983] (Bioassay, Mouse)	Bioassay	Mouse
A Palazzo, S Herter, L Grosmaire, R Jones, CR Frey, F Limani, M Bacac, P Umana, RJ Oldham, MJE Marshall, KL Cox, AH Turaj, MS Cragg, C Klein, MJ Carter, S Tannheimer The PI3K?-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo J. Immunol., 2018-02-16;0(0):. 2018-02-16 [PMID: 29453281] (Bioassay, Human)	Bioassay	Human
AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes Diabetologia, 2018-02-14;0(0):. 2018-02-14 [PMID: 29445851] (Cell Culture, Human, Mouse)	Cell Culture	Human, Mouse
TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee Changes in the Anti-Allergic Activities of Sesame by Bioconversion Nutrients, 2018-02-14;10(2):. 2018-02-14 [PMID: 29443928] (Bioassay, Human)	Bioassay	Human
CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, LC Chan, T Kim, SS Chang, HH Lee, CK Chou, YL Liu, HC Yeh, EP Perillo, AK Dunn, CW Kuo, KH Khoo, JL Hsu, Y Wu, JM Hsu, H Yamaguchi, TH Huang, AA Sahin, GN Hortobagyi, SS Yoo, MC Hung Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1 Cancer Cell, 2018-02-12;33(2):187-201.e10. 2018-02-12 [PMID: 29438695] (Bioassay, Human)	Bioassay	Human
WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature Front Immunol, 2018-01-29;9(0):80. 2018-01-29 [PMID: 29434599] (Cell Culture, Human)	Cell Culture	Human
T Oth, THPM Habets, WTV Germeraad, MI Zonneveld, GMJ Bos, J Vanderloch Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-? BMC Immunol., 2018-02-13;19(1):8. 2018-02-13 [PMID: 29433450] (Bioassay, Human)	Bioassay	Human
N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4 Front Immunol, 2018-01-24;9(0):11. 2018-01-24 [PMID: 29416536] (Bioassay, Human)	Bioassay	Human
M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann Virus-like infection induces human ? cell dedifferentiation JCI Insight, 2018-02-08;3(3):. 2018-02-08 [PMID: 29415896] (Bioassay, Human)	Bioassay	Human
C Breuker, C Amouzou, O Fabre, K Lambert, P Seyer, A Bourret, T Salehzada, J Mercier, A Sultan, C Bisbal Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women Metab. Clin. Exp., 2018-02-02;0(0):. 2018-02-02 [PMID: 29410345] (Cell Culture, Human)	Cell Culture	Human
X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells J Cancer, 2018-01-01;9(2):367-374. 2018-01-01 [PMID: 29344283] (Bioassay, Human)	Bioassay	Human
TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock J Innate Immun, 2018-01-16;0(0):. 2018-01-16 [PMID: 29334679] (Bioassay, Human)	Bioassay	Human
Y Sun, J Jiang, P Tien, W Liu, J Li INF-?: A new spotlight in innate immunity against influenza virus infection Protein Cell, 2018-10-01;0(0):. 2018-10-01 [PMID: 29332267] (Bioassay, Human)	Bioassay	Human
R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis Cardiovasc Diabetol, 2017-11-06;16(1):143. 2017-11-06 [PMID: 29110715] (Bioassay, Human)	Bioassay	Human
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, M Bowden, J Deng, H Liu, D Miao, MX He, W Walker, G Zhang, T Tian, C Cheng, Z Wei, S Palakurthi, M Bittinger, H Vitzthum, JW Kim, A Merlino, M Quinn, C Venkataram, JA Kaplan, A Portell, PC Gokhale, B Phillips, A Smart, A Rotem, RE Jones, L Keogh, M Anguiano, L Stapleton, Z Jia, M Barzily-Ro, I Cañadas, TC Thai, MR Hammond, R Vlahos, ES Wang, H Zhang, S Li, GJ Hanna, W Huang, MP Hoang, A Piris, JP Eliane, AO Stemmer-Ra, L Cameron, MJ Su, P Shah, B Izar, M Thakuria, NR LeBoeuf, G Rabinowits, V Gunda, S Parangi, JM Cleary, BC Miller, S Kitajima, R Thummalapa, B Miao, TU Barbie, V Sivathanu, J Wong, WG Richards, R Bueno, CH Yoon, J Miret, M Herlyn, LA Garraway, EM Van Allen, GJ Freeman, PT Kirschmeie, JH Lorch, PA Ott, FS Hodi, KT Flaherty, RD Kamm, GM Boland, KK Wong, D Dornan, CP Paweletz, DA Barbie Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids Cancer Discov, 2017-11-03;0(0):. 2017-11-03 [PMID: 29101162] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
A Basu, N Jain, BS Tolbert, AA Komar, B Mazumder Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon Nucleic Acids Res., 2017-12-15;0(0):. 2017-12-15 [PMID: 29069516] (Bioassay, Human)	Bioassay	Human
NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis Sci Rep, 2017-10-23;7(1):13831. 2017-10-23 [PMID: 29062018] (Bioassay, Human)	Bioassay	Human
F Liu, Q Niu, X Fan, C Liu, J Zhang, Z Wei, W Hou, TD Kanneganti, ML Robb, JH Kim, NL Michael, J Sun, L Soong, H Hu Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor J. Immunol., 2017-09-25;0(0):. 2017-09-25 [PMID: 28947539] (Bioassay, Human)	Bioassay	Human
Y Qin, M Li, SL Zhou, W Yin, Z Bian, HB Shu SPI-2/CrmA inhibits IFN-? induction by targeting TBK1/IKK? Sci Rep, 2017-09-05;7(1):10495. 2017-09-05 [PMID: 28874755] (Bioassay, Human)	Bioassay	Human
N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency Sci Rep, 2017-08-15;7(1):8153. 2017-08-15 [PMID: 28811575] (Bioassay, Human)	Bioassay	Human
MW Tang, S Garcia, B Malvar Fer, DM Gerlag, PP Tak, KA Reedquist Rheumatoid arthritis and psoriatic arthritis synovial fluid stimulates prolactin production by macrophages J. Leukoc. Biol., 2017-06-22;0(0):. 2017-06-22 [PMID: 28642278] (Bioassay, Human)	Bioassay	Human
JD Widdringto, A Gomez-Dura, JS Steyn, A Pyle, MH Ruchaud-Sp, J Scott, SV Baudouin, AJ Rostron, J Simpson, PF Chinnery F Mitochondrial DNA depletion induces innate immune dysfunction rescued by interferon-? J. Allergy Clin. Immunol., 2017-06-17;0(0):. 2017-06-17 [PMID: 28629747] (Bioassay, Human)	Bioassay	Human
HM Rostam, PM Reynolds, MR Alexander, N Gadegaard, AM Ghaemmagha Image based Machine Learning for identification of macrophage subsets Sci Rep, 2017-06-14;7(1):3521. 2017-06-14 [PMID: 28615717] (Bioassay, Human)	Bioassay	Human
A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors JCI Insight, 2017-06-15;2(12):. 2017-06-15 [PMID: 28614795] (Bioassay, Human)	Bioassay	Human
Q Wu, A Allouch, A Paoletti, C Leteur, C Mirjolet, I Martins, L Voisin, F Law, H Dakhli, E Mintet, M Thoreau, Z Muradova, M Gauthier, O Caron, F Milliat, DM Ojcius, F Rosselli, E Solary, N Modjtahedi, E Deutsch, JL Perfettini NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy Cell Death Differ., 2017-06-02;0(0):. 2017-06-02 [PMID: 28574504] (Bioassay, Human)	Bioassay	Human
JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma Mol. Cancer Ther., 2017-06-01;0(0):. 2017-06-01 [PMID: 28572167] (Bioassay, Human)	Bioassay	Human
F Arruda-Sil, F Bianchetto, S Gasperini, S Polletti, E Cosentino, N Tamassia, MA Cassatella Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNF? Front Cell Infect Microbiol, 2017-05-12;7(0):176. 2017-05-12 [PMID: 28553619] (Bioassay, Human)	Bioassay	Human
N Hakimzadeh, J Elias, GWM Wijntjens, R Theunissen, A van Weert, MW Smulders, N van den Ak, PD Moerland, HJ Verberne, LP Hoebers, JPS Henriques, AM van der La, M Ilhan, M Post, SCAM Bekkers, JJ Piek Monocytic microRNA profile associated with coronary collateral artery function in chronic total occlusion patients Sci Rep, 2017-05-08;7(1):1532. 2017-05-08 [PMID: 28484274] (Bioassay, Human)	Bioassay	Human
X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions J Extracell Vesicles, 2017-04-21;6(1):1314073. 2017-04-21 [PMID: 28473886] (Bioassay, Human)	Bioassay	Human
E El Darzi, S Bazzi, S Daoud, KS Echtay, GM Bahr Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-?, interleukin-4, tumor necrosis factor-?, or muramyl dipeptide Int J Immunopathol Pharmacol, 2017-04-28;0(0):3946320177076. 2017-04-28 [PMID: 28449603] (Bioassay, Human)	Bioassay	Human
E Nagy, Y Lei, E Martínez-M, SC Body, F Schlotter, M Creager, A Assmann, K Khabbaz, P Libby, GK Hansson, E Aikawa Interferon-? Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves Am. J. Pathol., 2017-04-19;0(0):. 2017-04-19 [PMID: 28431214] (Bioassay, Human)	Bioassay	Human
Y Arai, D Takahashi, K Asano, M Tanaka, M Oda, SBH Ko, MSH Ko, S Mandai, N Nomura, T Rai, S Uchida, E Sohara Salt suppresses IFN? inducible chemokines through the IFN?-JAK1-STAT1 signaling pathway in proximal tubular cells Sci Rep, 2017-04-20;7(0):46580. 2017-04-20 [PMID: 28425456] (Bioassay, Human)	Bioassay	Human
E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro Stem Cell Res Ther, 2017-04-17;8(1):79. 2017-04-17 [PMID: 28412968] (Bioassay, Human)	Bioassay	Human
A Raimondo, S Lembo, RD Caprio, G Donnarumma, G Monfrecola, N Balato, F Ayala, A Balato Psoriatic cutaneous inflammation promotes human monocyte differentiation into active osteoclasts, facilitating bone damage Eur. J. Immunol., 2017-05-02;0(0):. 2017-05-02 [PMID: 28386999] (Bioassay, Human)	Bioassay	Human
L Tian, A Goldstein, H Wang, H Ching Lo, I Sun Kim, T Welte, K Sheng, LE Dobrolecki, X Zhang, N Putluri, TL Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, WK Decker, C Zong, MT Lewis, XH Zhang Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming Nature, 2017-04-03;0(0):. 2017-04-03 [PMID: 28371798] (Bioassay, Human)	Bioassay	Human
JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36? Proc. Natl. Acad. Sci. U.S.A, 2017-03-13;114(13):E2748-E2757. 2017-03-13 [PMID: 28289191] (Bioassay, Human)	Bioassay	Human
AC Tecalco Cr, K Mejía-Barr Cell type-dependent regulation of free ISG15 levels and ISGylation J Cell Commun Signal, 2017-03-11;0(0):. 2017-03-11 [PMID: 28285335] (Bioassay, Human)	Bioassay	Human
BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps Allergy, 2017-04-04;0(0):. 2017-04-04 [PMID: 28258963] (Bioassay, Human)	Bioassay	Human
D Labrousse-, E Martínez-A, M Corral-Esc, R Bienes-Mar, J Berridy, L Serrano-Ov, E Conde, ML García-Ber, JM Giménez-Ba, AS Salinas-Sá, R Sánchez-Pr, M Yao, M Lasa, MJ Calzada VHL promotes immune response against renal cell carcinoma via NF-?B-dependent regulation of VCAM-1 J. Cell Biol, 2017-02-24;0(0):. 2017-02-24 [PMID: 28235946] (Bioassay, Human)	Bioassay	Human
MA Schumacher, M Hedl, C Abraham, JK Bernard, PR Lozano, JJ Hsieh, D Almohazey, EB Bucar, S Punit, PJ Dempsey, MR Frey ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation Cell Death Dis, 2017-02-23;8(2):e2622. 2017-02-23 [PMID: 28230865] (Bioassay, Human)	Bioassay	Human
X Zhang, Y Yang, L Zhang, Y Lu, Q Zhang, D Fan, Y Zhang, Y Zhang, Z Ye, D Xiong Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan J Hematol Oncol, 2017-02-23;10(1):56. 2017-02-23 [PMID: 28228105] (Bioassay, Human)	Bioassay	Human
MH van Atteku, S Terpstra, E Slinger, M von Linder, PD Moerland, A Jongejan, AP Kater, E Eldering Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia Oncogene, 2017-02-13;0(0):. 2017-02-13 [PMID: 28192408] (Bioassay, Human)	Bioassay	Human
HC Hsia, JE Hutti, AS Baldwin Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity J. Biol. Chem, 2017-02-10;0(0):. 2017-02-10 [PMID: 28188292] (Bioassay, Human)	Bioassay	Human
MA Terkawi, R Takano, A Furukawa, F Murakoshi, K Kato Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum Sci Rep, 2017-02-09;7(0):41772. 2017-02-09 [PMID: 28181499] (Bioassay, Human)	Bioassay	Human
A Qin, DH Lai, Q Liu, W Huang, YP Wu, X Chen, S Yan, H Xia, G Hide, ZR Lun, FJ Ayala, AP Xiang Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii Proc. Natl. Acad. Sci. U.S.A, 2017-01-25;0(0):. 2017-01-25 [PMID: 28123064] (Bioassay, Human)	Bioassay	Human
MJ Bae, S Ryu, HJ Kim, SI Cha, CH Kim, J Lee Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages Tuberc Respir Dis (Seoul), 2016-12-30;80(1):77-82. 2016-12-30 [PMID: 28119750] (Bioassay, Human)	Bioassay	Human
Y Zhang, Y Kong, S Liu, L Zeng, L Wan, Z Zhang Curcumin induces apoptosis in human leukemic cell lines through an IFIT2-dependent pathway Cancer Biol. Ther, 2017-01-10;0(0):1-8. 2017-01-10 [PMID: 28071969] (Bioassay, Human)	Bioassay	Human
J Huang, F Shen, H Huang, C Ling, G Zhang Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC Oncotarget, 2017-02-21;8(8):13116-13125. 2017-02-21 [PMID: 28061450] (Bioassay, Human)	Bioassay	Human
AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin IFN type I and II induce BAFF secretion from human decidual stromal cells Sci Rep, 2017-01-06;7(0):39904. 2017-01-06 [PMID: 28057926] (Bioassay, Human)	Bioassay	Human
Nicholas M Plugis Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: Implications for Celiac Disease J. Biol. Chem, 2016-12-21;0(0):. 2016-12-21 [PMID: 28003361] (Bioassay, Human)	Bioassay	Human
Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells PLoS ONE, 2016-12-01;11(12):e0167361. 2016-12-01 [PMID: 27907087] (Bioassay, Human)	Bioassay	Human
Mark L Chiu Fc engineering approaches to enhance the agonism and effector functions of an anti-OX40 antibody J. Biol. Chem., 2016-11-17;0(0):. 2016-11-17 [PMID: 27856634] (Bioassay, Human)	Bioassay	Human
Andrea Todisco Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2. 2016-11-17 [PMID: 27856416] (Bioassay, Human)	Bioassay	Human
Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells Int J Mol Sci, 2016-11-12;17(11):. 2016-11-12 [PMID: 27845745] (Bioassay, Human)	Bioassay	Human
Robert Sabat MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations Mediators Inflamm., 2016-10-23;2016(0):4097574. 2016-10-23 [PMID: 27843200] (Bioassay, Human)	Bioassay	Human
Qiyun Zhu Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-? Signaling Pathways by Targeting VISA J. Immunol., 2016-11-07;0(0):. 2016-11-07 [PMID: 27821666] (Bioassay, Human)	Bioassay	Human
Susheela Tridandapa Interferon-? Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells J. Biol. Chem., 2016-10-25;291(49):25656-25666. 2016-10-25 [PMID: 27780867] (Bioassay, Human)	Bioassay	Human
Programmed death-ligand 1 (PD-L1) characterization of circulating tumor cells (CTCs) in muscle invasive and metastatic bladder cancer patients BMC Cancer, 2016-09-22;16(1):744. 2016-09-22 [PMID: 27658492] (Bioassay, Human)	Bioassay	Human
Interferon-? blocks signalling through PDGFR? in human brain pericytes J Neuroinflammation, 2016-09-21;13(1):249. 2016-09-21 [PMID: 27654972] (Bioassay, Human)	Bioassay	Human
TLR3 preconditioning enhances the therapeutic efficacy of umbilical cord mesenchymal stem cells in TNBS-induced colitis via the TLR3-Jagged-1-Notch-1 pathway Mucosal Immunol, 2016-09-21;0(0):. 2016-09-21 [PMID: 27649928] (Bioassay, Human)	Bioassay	Human
Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells Elife, 2016-09-20;5(0):. 2016-09-20 [PMID: 27644592] (Bioassay, Human)	Bioassay	Human
Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic Proc Natl Acad Sci USA, 2016-09-06;113(38):10643-10648. 2016-09-06 [PMID: 27601677] (Bioassay, Human)	Bioassay	Human
MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA Mol Immunol, 2016-08-16;77(0):205-212. 2016-08-16 [PMID: 27541693] (Bioassay, Human)	Bioassay	Human
Identification of a major epitope by anti-interferon-? autoantibodies in patients with mycobacterial disease Nat Med, 2016-08-15;0(0):. 2016-08-15 [PMID: 27525523] (Western Blot, Human)	Western Blot	Human
PD-1/PD-L1 blockade enhances T cell activity and antitumor efficacy of imatinib in gastrointestinal stromal tumors Clin Cancer Res, 2016-07-28;0(0):. 2016-07-28 [PMID: 27470968] (Bioassay, Human)	Bioassay	Human
Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype Sci Rep, 2016-07-19;6(0):29712. 2016-07-19 [PMID: 27431276] (Bioassay, Human)	Bioassay	Human
G Karina Chimal-Ram Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes J Immunol Res, 2016-06-08;2016(0):6031486. 2016-06-08 [PMID: 27376091] (Bioassay, Human)	Bioassay	Human
Martine Schrøder CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits PLoS ONE, 2016-06-16;11(6):e0157387. 2016-06-16 [PMID: 27311059] (Bioassay, Human)	Bioassay	Human
Takuya Matsumoto Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages Arthritis Res Ther, 2016-06-07;18(1):133. 2016-06-07 [PMID: 27267914] (Bioassay, Mouse)	Bioassay	Mouse
Kellie N Smith Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells MBio, 2016-05-31;7(3):. 2016-05-31 [PMID: 27247230] (Bioassay, Human)	Bioassay	Human
M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu, D Ren, B Yu, L Zheng, X Hu, W Shi, J Xu Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis Stem Cell Res Ther, 2016-04-23;7(1):63. 2016-04-23 [PMID: 27107963] (Bioassay, Human)	Bioassay	Human
SW Jackson, HM Jacobs, T Arkatkar, EM Dam, NE Scharping, NS Kolhatkar, B Hou, JH Buckner, DJ Rawlings B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6 J Exp Med, 2016-04-11;0(0):. 2016-04-11 [PMID: 27069113] (Bioassay, Human)	Bioassay	Human
Guo Z, Zheng L, Liao X, Geller D Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex. PLoS ONE, 2016-01-11;11(1):e0146640. 2016-01-11 [PMID: 26751080] (Bioassay, Human)	Bioassay	Human
Maleki Vareki S, Chen D, Di Cresce C, Ferguson P, Figueredo R, Pampillo M, Rytelewski M, Vincent M, Min W, Zheng X, Koropatnick J IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells. PLoS ONE, 2015-11-18;10(11):e0143435. 2015-11-18 [PMID: 26579709] (In Vivo, Mouse)	In Vivo	Mouse
Nagarsheth N, Peng D, Kryczek I, Wu K, Li W, Zhao E, Zhao L, Wei S, Frankel T, Vatan L, Szeliga W, Dou Y, Owens S, Marquez V, Tao K, Huang E, Wang G, Zou W PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. Cancer Res, 2015-11-13;76(2):275-82. 2015-11-13 [PMID: 26567139] (Bioassay, Human)	Bioassay	Human
Rhein B, Powers L, Rogers K, Anantpadma M, Singh B, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey R, Monick M, Maury W Interferon-gamma Inhibits Ebola Virus Infection. PLoS Pathog, 2015-11-12;11(11):e1005263. 2015-11-12 [PMID: 26562011] (Bioassay, Human)	Bioassay	Human
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Howland S, Poh C, Renia L Activated Brain Endothelial Cells Cross-Present Malaria Antigen. PLoS Pathog, 2015-06-05;11(6):e1004963. 2015-06-05 [PMID: 26046849] (Bioassay, Human)	Bioassay	Human
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Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes. J. Immunol., 2006-12-01;177(11):7665-72. 2006-12-01 [PMID: 17114436] (Bioassay, Human)	Bioassay	Human
Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression. J. Endocrinol., 2006-10-01;191(1):65-81. 2006-10-01 [PMID: 17065390] (Bioassay, Hamster)	Bioassay	Hamster
Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, Yagi J, Dianzani U ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells. Eur. J. Immunol., 2006-10-01;36(10):2601-12. 2006-10-01 [PMID: 17013990] (Bioassay, Human)	Bioassay	Human
Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway. J. Cell. Physiol., 2007-01-01;210(1):192-200. 2007-01-01 [PMID: 17013806] (Bioassay, Human)	Bioassay	Human
Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia, 2006-11-01;54(6):619-29. 2006-11-01 [PMID: 16944452] (Bioassay, Human)	Bioassay	Human
Ebert EC, Mehta V Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell. Immunol., 2006-08-17;241(1):7-13. 2006-08-17 [PMID: 16914126] (Bioassay, Human)	Bioassay	Human
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 2006-06-16;120(2):220-31. 2006-06-16 [PMID: 16782408] (ELISA (Standard))	ELISA (Standard)
Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol., 2006-05-01;36(5):1309-23. 2006-05-01 [PMID: 16619290] (Bioassay, Human)	Bioassay	Human
Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood, 2006-04-13;108(3):947-55. 2006-04-13 [PMID: 16614246] (Bioassay, Human)	Bioassay	Human
Cho ML, Min SY, Chang SH, Kim KW, Heo SB, Lee SH, Park SH, Cho CS, Kim HY Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression. Immunol. Lett., 2006-03-03;105(2):159-66. 2006-03-03 [PMID: 16564576] (Bioassay, Human)	Bioassay	Human
Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J. Virol., 2005-10-01;79(20):12828-39. 2005-10-01 [PMID: 16188985] (Bioassay, Primate - Chlorocebus pygerythrus (Vervet Monkey))	Bioassay	Primate - Chlorocebus pygerythrus (Vervet Monkey)
Ameredes BT, Calhoun WJ Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72. 2005-07-01 [PMID: 15990776] (Bioassay, Human)	Bioassay	Human
Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. Crit. Care Med., 2005-06-01;33(6):1359-64. 2005-06-01 [PMID: 15942356] (Bioassay, Human)	Bioassay	Human
Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 2005-05-01;52(5):1504-16. 2005-05-01 [PMID: 15880822] (Bioassay, Human)	Bioassay	Human
Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum., 2005-03-01;52(3):770-8. 2005-03-01 [PMID: 15751070] (Bioassay, Human)	Bioassay	Human
Radstake TR, Roelofs MF, Jenniskens YM, van Riel PL, Barrera P Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma. Arthritis Rheum., 2004-12-01;50(12):3856-65. 2004-12-01 [PMID: 15593217] (Bioassay, Human)	Bioassay	Human
Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med., 2004-11-22;200(11):1419-26. 2004-11-22 [PMID: 15557347] (Bioassay, Human)	Bioassay	Human
Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. J. Immunol., 2004-11-01;173(9):5810-7. 2004-11-01 [PMID: 15494534] (Bioassay, Human)	Bioassay	Human
Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood, 2004-09-09;105(2):830-7. 2004-09-09 [PMID: 15358625] (Bioassay, Human)	Bioassay	Human
Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human)	Bioassay	Human
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Bioassay, Human)	Bioassay	Human
Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood, 2004-03-25;104(2):314-20. 2004-03-25 [PMID: 15044249] (Bioassay, Human)	Bioassay	Human
Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem. J., 2004-06-01;380(0):425-33. 2004-06-01 [PMID: 14992689] (Bioassay, Human)	Bioassay	Human
Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia. J. Neuroimmunol., 2004-03-01;148(1):127-39. 2004-03-01 [PMID: 14975593] (Bioassay, Human)	Bioassay	Human
Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (ELISA (Standard))	ELISA (Standard)
Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22. 2004-01-12 [PMID: 14722222] (Bioassay, Human)	Bioassay	Human
Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood, 2003-09-25;103(3):1089-98. 2003-09-25 [PMID: 14512323] (Binding Assay, Human)	Binding Assay	Human
McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J. Clin. Invest., 2003-08-01;112(4):598-607. 2003-08-01 [PMID: 12925700] (Bioassay, Human)	Bioassay	Human
Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood, 2003-07-31;102(12):4084-9. 2003-07-31 [PMID: 12893768] (Bioassay, Human)	Bioassay	Human
Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma. Blood, 2003-07-24;102(10):3737-42. 2003-07-24 [PMID: 12881320] (Bioassay, Human)	Bioassay	Human
Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc. Natl. Acad. Sci. U.S.A., 2003-07-23;100(16):9452-7. 2003-07-23 [PMID: 12878725] (Bioassay, Human)	Bioassay	Human
Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection. J. Immunol., 2002-12-01;169(11):6361-8. 2002-12-01 [PMID: 12444143] (Bioassay, Human)	Bioassay	Human
Wang XB, Giscombe R, Yan Z Expression of CTLA-4 by human monocytes. Scand. J. Immunol., 2002-01-01;55(1):53-60. 2002-01-01 [PMID: 11841692] (Bioassay, Human)	Bioassay	Human
Barcena A, Park SW, Banapour B, Muench MO, Mechetner E Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood, 1996-09-15;88(6):2013-25. 1996-09-15 [PMID: 8822920] (Bioassay, Human)	Bioassay	Human
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Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	In vitro bioactivity in cell culture		06/09/2019	View Summary Application In vitro bioactivity in cell culture Lot RAX2218012 Comments Comments The expression of HLA-DR increased with MDAMB231 cells incubated with 1000 IU mL–1 IFN-gamma for 72 h
Enlarge	5 reviewed by: Verified Customer	CellProlif		10/07/2018	View Summary Application Cell Proliferation Lot RAX2218012 Comments Comments HT-29 Cell lines were treated with 100 U/ml IFN gamma , after which HLA-DR expression was examined by flow cytometer

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