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MAT2A Antibody [DyLight 350]

 
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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Pm, ChSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-94158AF350
Alexa Fluor 405
NB110-94158AF405
Alexa Fluor 488
NB110-94158AF488
Alexa Fluor 532
NB110-94158AF532
Alexa Fluor 594
NB110-94158AF594
Alexa Fluor 647
NB110-94158AF647
Alexa Fluor 700
NB110-94158AF700
Alexa Fluor 750
NB110-94158AF750
Allophycocyanin
NB110-94158APC
Biotin
NB110-94158B
CoraFluor 1
NB110-94158CL1
DyLight 405
NB110-94158V
DyLight 488
NB110-94158G
DyLight 550
NB110-94158R
DyLight 594
NB110-94158DL594
DyLight 650
NB110-94158C
DyLight 680
NB110-94158FR
DyLight 755
NB110-94158IR
FITC
NB110-94158F
HRP
NB110-94158H
Janelia Fluor 525
NB110-94158JF525
Janelia Fluor 549
NB110-94158JF549
Janelia Fluor 585
NB110-94158JF585
Janelia Fluor 635
NB110-94158JF635
Janelia Fluor 646
NB110-94158JF646
Janelia Fluor 669
NB110-94158JF669
PE
NB110-94158PE
PerCP
NB110-94158PCP
Unconjugated
NB110-94158
mFluor Violet 450 SE
NB110-94158MFV450
mFluor Violet 500 SE
NB110-94158MFV500
mFluor Violet 610 SE
NB110-94158MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-94158
BSA Free
NB110-94158
BSA Free
NB110-94158SS
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MAT2A Antibody [DyLight 350] Summary

Immunogen
Synthetic peptide made to an N-terminal portion of human MAT2A (within residues 1-100). [Swiss-Prot# P31153]
Localization
Cytoplasm
Predicted Species
Chicken (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAT2A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID: 29133573).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MAT2A Antibody [DyLight 350]

  • AdoMet synthase 2
  • AMS2
  • EC 2.5.1.6
  • MAT 2
  • MAT2A
  • MATA2
  • MATA2SAMS2adoMet synthetase 2
  • MATII
  • MAT-II
  • Methionine adenosyltransferase 2
  • Methionine adenosyltransferase II
  • methionine adenosyltransferase II, alpha
  • S-adenosylmethionine synthase isoform type-2
  • S-adenosylmethionine synthetase isoform type-2
  • SAMS2

Background

MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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[DyLight 350]
NB110-94158UV
MAT2A Antibody [DyLight 350]
Species: Hu, Mu, Rt, Po, Bv, Pm, Ch
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on MAT2A.

Check out the latest blog posts on MAT2A.
MAT2A - A Protien Coding Gene
The enzyme S-adenosylmethionine synthetase, or MAT, catalyzes the formation of S- adenosylmethionine (AdoMet or SAMe) from methionine and ATP. AdoMet is the principal biological source of synthesized methyl, and is found in all cells but most prominen...  Read full blog post.
MAT2a, MAT2b, HIF-1 alpha: Roles in Liver Cancer and DNA methylation
Methionine Adenosyltransferase II alpha, also known as MAT2a, is a catalytic subunit of methionine adenosyltransferase (MAT) and essential enzyme for the catalysis of the principle biological methyl donor, S-adenosylmethionine (SAM) from methionine an...  Read full blog post.
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Bioinformatics

Gene Symbol MAT2A