Human TLR2 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 7 of 7.

Publications using DY2616	Applications	Species
Kos, M;Bojarski, K;Mertowska, P;Mertowski, S;Tomaka, P;Dziki, ?;Grywalska, E; Immunological Strategies in Gastric Cancer: How Toll-like Receptors 2, -3, -4, and -9 on Monocytes and Dendritic Cells Depend on Patient Factors? Cells 2024-10-16 [PMID: 39451226] (Human)		Human
Kos, M;Bojarski, K;Mertowska, P;Mertowski, S;Tomaka, P;Dziki, ?;Grywalska, E; New Horizons in the Diagnosis of Gastric Cancer: The Importance of Selected Toll-like Receptors in Immunopathogenesis Depending on the Stage, Clinical Subtype, and Gender of Newly Diagnosed Patients International journal of molecular sciences 2024-08-27 [PMID: 39273213] (Human)		Human
WL Chen, KL Lee, KS Lai, JH Tsai, SH Hsiao, CL Chung Toll-like Receptor 2 Mediates VEGF Overexpression and Mesothelial Hyperpermeability in Tuberculous Pleural Effusion International Journal of Molecular Sciences, 2023-02-02;24(3):. 2023-02-02 [PMID: 36769168] (Human)		Human
A Drannik, J Martin, R Peterson, X Ma, F Jiang, J Turnbull Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function PLoS ONE, 2017-02-07;12(2):e0171668. 2017-02-07 [PMID: 28170441] (Human)		Human
Raby A, Colmont C, Kift-Morgan A, Kohl J, Eberl M, Fraser D, Topley N, Labeta M Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis. J Am Soc Nephrol, 2016-07-18;28(2):461-478. 2016-07-18 [PMID: 27432741] (Human)		Human
Langjahr P, Diaz-Jimenez D, De la Fuente M, Rubio E, Golenbock D, Bronfman F, Quera R, Gonzalez M, Hermoso M Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production. PLoS ONE, 2014-12-22;9(12):e104624. 2014-12-22 [PMID: 25531754] (Human, Mouse)		Human, Mouse
Koc M, Toprak A, Arikan H, Odabasi Z, Elbir Y, Tulunay A, Asicioglu E, Eksioglu-Demiralp E, Glorieux G, Vanholder R, Akoglu E Toll-like receptor expression in monocytes in patients with chronic kidney disease and haemodialysis: relation with inflammation. Nephrol. Dial. Transplant., 2010-08-20;26(3):955-63. 2010-08-20 [PMID: 20729266] (Human)		Human

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Patricia Carulla Martí			06/22/2023	View Summary Sample Tested Cell lysate from Human Keratinocytes (Hacat) in presence or absence of IFNg,Cultured Human Keratinocytes Lot P279149

Array DY2616

• TLR2 Antibodies
• TLR2 ELISA Kits
• TLR2 Lysates
• TLR2 Proteins
• TLR2 ELISA
• TLR2 Proteins and Enzymes