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HLA DP Antibody (PD00-70)

Images

 
Immunohistochemistry: HLA DP Antibody (PD00-70) [NBP3-32434] - Immunohistochemical analysis of paraffin-embedded human tonsil tissue with Rabbit anti-HLA DP antibody (NBP3-32434) at 1/200 dilution. The section was ...read more
Flow Cytometry: HLA DP Antibody (PD00-70) [NBP3-32434] - Flow cytometric analysis of Daudi cells labeling HLA DP. Cells were fixed and permeabilized. Then stained with the primary antibody (NBP3-32434, 1ug/ml) (red) ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC
Clone
PD00-70
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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HLA DP Antibody (PD00-70) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Synthetic peptide. (Uniprot: P20036)
Localization
Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome membrane, Lysosome membrane.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HLA-DPA1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:500-1:1000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:200-1:500
Theoretical MW
29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH7.4), 0.1% BSA and 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for HLA DP Antibody (PD00-70)

  • DP alpha 1 chain
  • HLA class II histocompatibility antigen, DP alpha chain
  • HLADP
  • HLA-SB alpha chain
  • major histocompatibility complex, class II, DP alpha 1
  • MHC class II antigen
  • MHC class II DP3-alpha
  • MHC class II DPA1
  • MHC class II HLA-DPA1 antigen
  • Primed lymphocyte test-1

Background

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a vital role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells and macrophages). Within the DP molecule the alpha and beta chain contain the polymorphisms governing the peptide binding specificities, resulting in up to 4 different molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-32434

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Bioinformatics

Gene Symbol HLA-DPA1