CCR3 Antibody

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publications 1 - 2 of 2.

Publications using NBP2-15764	Applications	Species
Sun G, Wang Y, Yang L et al. Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD Cell reports 2023-07-25 [PMID: 37421620] (IHC-P, Human) Details: 1:100 dilution	IHC-P	Human
Greenman R, Segal-Salto M, Barashi N et al. CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis JCI insight 2023-06-22 [PMID: 37345655] (IHC-P, Human)	IHC-P	Human

Array NBP2-15764

• CCR3 Antibodies
• CCR3 ELISA Kits
• CCR3 Lysate
• CCR3 Proteins