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Mouse IL-5 Quantikine ELISA Kit, 2 Plate

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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse IL-5 Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse IL-5 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-5 in cell culture supernates and mouse serum. It contains Sf 21-expressed recombinant mouse IL-5 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant mouse IL-5. Results obtained using natural mouse IL-5 showed linea...r curves that were parallel to the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-5.
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Specificity
Natural and recombinant mouse IL-5
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il5

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using M5000.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-5 Quantikine ELISA Kit, 2 Plate

  • BCDF mu
  • B-cell differentiation factor I
  • BCGFII
  • EDF
  • Eo-CSF
  • Eosinophil differentiation factor
  • IL5
  • IL-5
  • IL-5T-cell replacing factor
  • interleukin 5 (colony-stimulating factor, eosinophil)
  • interleukin-5
  • TRF
  • TRFB cell differentiation factor I

Background

IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for IL-5 (M5000)(92)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Transgenic Mouse.


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Human
(1)
Mouse
(88)
Rat
(3)
Transgenic Mouse
(2)
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Showing Publications 1 - 10 of 92. Show All 92 Publications.
Publications using M5000 Applications Species
Cao, Z;Wang, J;Liu, X;Liu, Y;Li, F;Liu, M;Chiu, S;Jin, X; Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way mBio 2024-05-10 [PMID: 38727220] (Mouse) Mouse
Jin, J;Fan, YJ;Nguyen, TV;Yu, ZN;Song, CH;Lee, SY;Shin, HS;Chai, OH; Fallopia japonica Root Extract Ameliorates Ovalbumin-Induced Airway Inflammation in a CARAS Mouse Model by Modulating the IL-33/TSLP/NF-?B Signaling Pathway International journal of molecular sciences 2023-08-07 [PMID: 37569890] (Mouse) Mouse
Irie, M;Kabata, H;Sasahara, K;Kurihara, M;Shirasaki, Y;Kamatani, T;Baba, R;Matsusaka, M;Koga, S;Masaki, K;Miyata, J;Araki, Y;Kikawada, T;Kabe, Y;Suematsu, M;Yamagishi, M;Uemura, S;Moro, K;Fukunaga, K; Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s Cell reports 2023-06-07 [PMID: 37294636] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Y Song, J Jiang, Q Bai, S Liu, Y Zhang, C Xu, H Piao, L Li, G Yan Gene expression profiles and bioinformatics analysis in lung samples from ovalbumin-induced asthmatic mice BMC pulmonary medicine, 2023-02-02;23(1):50. 2023-02-02 [PMID: 36726128] (Mouse) Mouse
KE Block, K Iijima, MJ Pierson, DA Walsh, R Tei, TA Kucaba, J Xu, MH Khan, C Staley, TS Griffith, HJ McSorley, H Kita, SC Jameson Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to allergens Nature Immunology, 2022-11-21;0(0):. 2022-11-21 [PMID: 36411381] (Mouse) Mouse
W Chang, H Lv, L Tan, Z Gao, P Liu, D Qin, W Zhang, Y Xu Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium Molecular Medicine Reports, 2022-09-30;26(5):. 2022-09-30 [PMID: 36177892] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
JO Lim, YH Kim, IS Lee, WI Kim, SJ Lee, SW Pak, IS Shin, T Kim Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9 Frontiers in Pharmacology, 2022-08-11;13(0):906916. 2022-08-11 [PMID: 36034804] (Mouse) Mouse
A Kanamori, F Tanaka, M Ominami, Y Nadatani, S Fukunaga, K Otani, S Hosomi, N Kamata, Y Nagami, K Taira, Y Fujiwara Psychological Stress Exacerbates Inflammation of the Ileum via the Corticotropin-Releasing Hormone-Mast Cell Axis in a Mouse Model of Eosinophilic Enteritis International Journal of Molecular Sciences, 2022-08-01;23(15):. 2022-08-01 [PMID: 35955675] (Mouse) Mouse
DH Lee, HK Park, HR Lee, H Sohn, S Sim, HJ Park, YS Shin, YK Kim, Y Choi, HS Park Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma Clinical and translational allergy, 2022-03-01;12(3):e12138. 2022-03-01 [PMID: 35344296] (Mouse) Mouse
JH Chang, HC Chuang, G Hsiao, TY Hou, CC Wang, SC Huang, BY Li, YL Lee Acteoside exerts immunomodulatory effects on dendritic cells via aryl hydrocarbon receptor activation and ameliorates Th2-mediated allergic asthma by inducing Foxp3+ regulatory T cells International immunopharmacology, 2022-02-03;106(0):108603. 2022-02-03 [PMID: 35123286] (Mouse) Mouse
Show All 92 Publications.

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Bioinformatics

Gene Symbol Il5