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CXCR3 Antibody (49801) [Unconjugated]

Name: CXCR3 Antibody (49801) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB160
Price: 469 USD

(71 Publications)

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Human PBMC lymphocytes were stained with (A) Mouse Anti-Human CXCR3 Monoclonal Antibody (Catalog # MAB160) or (B) Mouse IgG1 isotype control antibody (MAB002) followed by PE-conjugated anti-Mouse IgG Secondary Antibody ...read more

HEK293 human embryonic kidney cell line transfected with (A) human CXCR3 or (B) irrelevant transfectants and eGFP was stained with and either Mouse Anti-Human CXCR3 Monoclonal Antibody (Catalog # MAB160) followed by ...read more

CXCR3 was detected in immersion fixed paraffin-embedded sections of human tonsil using Human CXCR3 Monoclonal Antibody (Catalog # MAB160) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB ...read more

Recombinant Human CXCL11/I‑TAC (Catalog # 672-IT) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CXCR3 in a dose-dependent manner (orange line). The amount of cells that migrated through to the ...read more

Functional effects of IP-10 on PCCs(A) Expression of CXCR3 in PCCs, PSCs and HEK293-EBNA/CXCR3-B analyzed by Western Blot. alpha -tubulin was used as loading control. (B) Microphotographs of PCCs migrated through the ...read more

Infiltration of CXCR3+ cells in the lamina propria of small intestine mucosa.a. Confocal immunofluorescence for CXCR3 was performed in sections of duodenal biopsies from controls (i), untreated celiac patients (ii), and ...read more

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	Flow, IHC, B/N, CyTOF-ready
Clone	49801
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated
Concentration	LYOPH

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB160U-100UG

Alexa Fluor 405 FAB160V-100UG

Alexa Fluor 488 FAB160G-100

Alexa Fluor 488 FAB160G-025

Alexa Fluor 532 FAB160X

Alexa Fluor 594 FAB160T-100UG

Alexa Fluor 647 FAB160R-100UG

Alexa Fluor 700 FAB160N-100UG

Alexa Fluor 750 FAB160S-100UG

Allophycocyanin FAB160A-025

Allophycocyanin FAB160A-100

Allophycocyanin/Cy7 FAB160APCCY7

Biotin FAB160B

DyLight 350 FAB160D

DyLight 405 FAB160E

DyLight 488 FAB160K

DyLight 550 FAB160L

DyLight 594 FAB160M

DyLight 650 FAB160W

DyLight 680 FAB160Y

DyLight 755 FAB160Z

Fluorescein FAB160F-100

Fluorescein FAB160F-025

HRP FAB160H

Janelia Fluor 549 FAB160I

Janelia Fluor 646 FAB160J

PE/Atto594 FAB160PEATT594

PE/Cy5.5 FAB160PECY55

PE/Cy7 FAB160PECY7

Phycoerythrin FAB160P-100

Phycoerythrin FAB160P-025

mFluor Violet 450 SE FAB160MFV450

mFluor Violet 500 SE FAB160MFV500

mFluor Violet 610 SE FAB160MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Carrier Free FAB160G-100

Carrier Free FAB160S-100UG

Carrier Free FAB160T-100UG

Carrier Free FAB160U-100UG

Carrier Free FAB160V-100UG

Carrier Free MAB160-500

Carrier Free FAB160G-025

Carrier Free MAB160-SP

Carrier Free FAB160N-100UG

Carrier Free FAB160A-100

Carrier Free FAB160A-025

Carrier Free FAB160P-100

Carrier Free FAB160P-025

Carrier Free FAB160F-100

Carrier Free FAB160F-025

Carrier Free FAB160R-100UG

100% Guarantee on every product

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB160U-100UG
Alexa Fluor 405	FAB160V-100UG
Alexa Fluor 488	FAB160G-100
Alexa Fluor 488	FAB160G-025
Alexa Fluor 532	FAB160X
Alexa Fluor 594	FAB160T-100UG
Alexa Fluor 647	FAB160R-100UG
Alexa Fluor 700	FAB160N-100UG
Alexa Fluor 750	FAB160S-100UG
Allophycocyanin	FAB160A-025
Allophycocyanin	FAB160A-100
Allophycocyanin/Cy7	FAB160APCCY7
Biotin	FAB160B
DyLight 350	FAB160D
DyLight 405	FAB160E
DyLight 488	FAB160K
DyLight 550	FAB160L
DyLight 594	FAB160M
DyLight 650	FAB160W
DyLight 680	FAB160Y
DyLight 755	FAB160Z
Fluorescein	FAB160F-100
Fluorescein	FAB160F-025
HRP	FAB160H
Janelia Fluor 549	FAB160I
Janelia Fluor 646	FAB160J
PE/Atto594	FAB160PEATT594
PE/Cy5.5	FAB160PECY55
PE/Cy7	FAB160PECY7
Phycoerythrin	FAB160P-100
Phycoerythrin	FAB160P-025
mFluor Violet 450 SE	FAB160MFV450
mFluor Violet 500 SE	FAB160MFV500
mFluor Violet 610 SE	FAB160MFV610

CXCR3 Antibody (49801) [Unconjugated] Summary

Immunogen	NS0 mouse myeloma cell line transfected with human CXCR3 Met1-Leu368 Accession # P49682
Specificity	Detects human CXCR3.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	CXCR3
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

CyTOF-ready
Flow Cytometry 0.25 ug/10^6 cells
Immunohistochemistry 8-25 ug/mL
Neutralization 0.3-1.5 ug/mL

Publications

Read Publications using
MAB160 in the following applications:

Bioassay
1 publication
Cell Culture
1 publication
Flow Cytometry
19 publications
Functional Assay
2 publications
ICC
8 publications
IHC
7 publications
IHC-Fr
3 publications
IHC-P
7 publications
Neutralization
6 publications
Stimulation
1 publication
Western Blot
7 publications

Packaging, Storage & Formulations

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCR3 Antibody (49801) [Unconjugated]

CD183 antigen
CD183
chemokine (C-X-C motif) receptor 3
chemokine (C-X-C) receptor 3
CKR-L2IP-10 receptor
CMKAR3
C-X-C chemokine receptor type 3
CXCR3
CXC-R3
CXCR-3
G protein-coupled receptor 9CD182
GPR9
GPR9Mig-R
Interferon-inducible protein 10 receptor
IP10 receptor
IP10-R
Mig receptor
MigR

Background

CXCR3 is a G protein-coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10), and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells, and NK cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CXCR3 Antibody (MAB160)(71)

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Feline, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 11 applications: Bioassay, Cell Culture, Flow Cytometry, Functional Assay, ICC, IHC, IHC-Fr, IHC-P, Neutralization, Stimulation, Western Blot.

Showing Publications 1 - 10 of 71. Show All 71 Publications.

Publications using MAB160	Applications	Species
I Pietrafort, A Butera, L Gaddini, A Mennella, R Palazzo, D Campanile, K Stefananto, V Riccieri, R Lande, L Frasca CXCL4-RNA Complexes Circulate in Systemic Sclerosis and Amplify Inflammatory/Pro-Fibrotic Responses by Myeloid Dendritic Cells International Journal of Molecular Sciences, 2022-12-30;24(1):. 2022-12-30 [PMID: 36614095] (Stimulation, Human)	Stimulation	Human
DM Kaczor, R Kramann, TM Hackeng, LJ Schurgers, RR Koenen Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells International Journal of Molecular Sciences, 2022-01-06;23(2):. 2022-01-06 [PMID: 35054772] (ICC, Human)	ICC	Human
H Jayakumar, A Seetharama, S Sunder Sin, H Dhandapani, J Subramani, S Ganeshraja, R Thangaraja, P Ramanathan Combination of IDO1high and CCL19low expression in the tumor tissue reduces survival in HPV positive cervical cancer Journal of reproductive immunology, 2021-11-23;149(0):103454. 2021-11-23 [PMID: 34856521] (IHC, Human)	IHC	Human
A Dickhout, DM Kaczor, ACA Heinzmann, SLN Brouns, JWM Heemskerk, MAMJ van Zandvo, RR Koenen Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells International Journal of Molecular Sciences, 2021-07-08;22(14):. 2021-07-08 [PMID: 34298951] (Neutralization, Human)	Neutralization	Human
Jiaqing Yi, Xuanming Shi, Zhenyu Xuan, Jiang Wu Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma Cancer Letters 2021-02-01 [PMID: 33253789]
Andrew Cannon, Christopher M. Thompson, H. Carlo Maurer, Pranita Atri, Rakesh Bhatia, Sean West et al. CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma Clinical Cancer Research 2020-11-15 [PMID: 32873571]
Garrido-Martin EM, Mellows TWP, Clarke J et al. M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer J Immunother Cancer 7/1/2020 [PMID: 32699181]
J Gao, L Wu, S Wang, X Chen Role of Chemokine (C-X-C Motif) Ligand 10 (CXCL10) in Renal Diseases Mediators Inflamm., 2020-02-05;2020(0):6194864. 2020-02-05 [PMID: 32089645] (IHC, Human)	IHC	Human
F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3) Int J Mol Sci, 2019-10-24;20(21):. 2019-10-24 [PMID: 31653015] (Neutralization, Human)	Neutralization	Human
Denarda Dangaj, Marine Bruand, Alizée J. Grimm, Catherine Ronet, David Barras, Priyanka A. Duttagupta et al. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors Cancer Cell 6/10/2019 [PMID: 31185212]
R Lande, EY Lee, R Palazzo, B Marinari, I Pietrafort, GS Santos, Y Mattenberg, F Spadaro, K Stefananto, N Iannace, AM Dufour, M Falchi, M Bianco, E Botti, L Bianchi, M Alvarez, V Riccieri, ME Truchetet, G C L Wong, C Chizzolini, L Frasca CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-? production in systemic sclerosis Nat Commun, 2019-05-01;10(1):1731. 2019-05-01 [PMID: 31043596] (Cell Culture, Human)	Cell Culture	Human
Mudan Zhang, Xu Deng, Xinmeng Guan, Lanlan Geng, Ming Fu, Binman Zhang et al. Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4 Frontiers in Immunology 2018-12-19 [PMID: 30619292]
I Maricic, I Marrero, A Eguchi, R Nakamura, CD Johnson, S Dasgupta, CD Hernandez, PS Nguyen, AD Swafford, R Knight, AE Feldstein, R Loomba, V Kumar Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis J. Immunol., 2018-10-15;0(0):. 2018-10-15 [PMID: 30322964] (Flow Cytometry, Human)	Flow Cytometry	Human
JM Fox, F Kausar, A Day, M Osborne, K Hussain, A Mueller, J Lin, T Tsuchiya, S Kanegasaki, JE Pease CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration Sci Rep, 2018-06-21;8(1):9466. 2018-06-21 [PMID: 29930254] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
S Urra, MC Fischer, JR Martínez, L Véliz, P Orellana, A Solar, K Bohmwald, A Kalergis, C Riedel, AH Corvalán, JC Roa, R Fuentealba, CJ Cáceres, M López-Last, A León, N Droppelman, HE González Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis? Oncotarget, 2017-12-20;9(2):2445-2467. 12/20/2017 [PMID: 29416784]
T Ishikawa, T Okayama, N Sakamoto, M Ideno, K Oka, T Enoki, J Mineno, N Yoshida, K Katada, K Kamada, K Uchiyama, O Handa, T Takagi, H Konishi, S Kokura, K Uno, Y Naito, Y Itoh Phase I clinical trial of adoptive transfer of expanded natural killer cells in combination with IgG1 antibody in patients with gastric or colorectal cancer Int. J. Cancer, 2018-02-14;0(0):. 2018-02-14 [PMID: 29388200] (Flow Cytometry, Human)	Flow Cytometry	Human
F Bellora, A Dondero, MV Corrias, B Casu, S Regis, F Caliendo, A Moretta, M Cazzola, C Elena, L Vinti, F Locatelli, C Bottino, R Castriconi Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages J. Immunol., 2017-07-12;0(0):. 2017-07-12 [PMID: 28701512] (Flow Cytometry, Human)	Flow Cytometry	Human
H Bronger, A Karge, T Dreyer, D Zech, S Kraeft, S Avril, M Kiechle, M Schmitt Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells Oncol Lett, 2017-04-05;13(6):4224-4230. 2017-04-05 [PMID: 28599423] (IHC, Western Blot, Human)	IHC, Western Blot	Human
N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence Nat Commun, 2017-05-25;8(0):15380. 2017-05-25 [PMID: 28541275] (Functional Assay, Human)	Functional Assay	Human
C Windmüller, D Zech, S Avril, M Boxberg, T Dawidek, B Schmalfeld, M Schmitt, M Kiechle, H Bronger CXCR3 mediates ascites-directed tumor cell migration and predicts poor outcome in ovarian cancer patients Oncogenesis, 2017-05-15;6(5):e331. 2017-05-15 [PMID: 28504691] (Neutralization, Western Blot, Human)	Neutralization, Western Blot	Human
JH Han, CH Suh, JY Jung, MH Ahn, MH Han, JE Kwon, H Yim, HA Kim Elevated circulating levels of the interferon-?-induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still's disease Sci Rep, 2017-04-24;7(0):46652. 2017-04-24 [PMID: 28436448] (IHC, Human)	IHC	Human
W Szczeklik, B Jakie?a, K Wawrzycka-, M Sanak, M Hubalewska, A Padjas, M Surmiak, K Szczeklik, J Sznajd, J Musia? Skewing towards Treg and Th2 responses is a characteristic feature of sustained remission in ANCA-positive granulomatosis with polyangiitis Eur. J. Immunol, 2017-02-27;0(0):. 2017-02-27 [PMID: 28155222] (Flow Cytometry, Human)	Flow Cytometry	Human
Valentina Cecchinato Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization J. Immunol, 2016-11-28;0(0):. 2016-11-28 [PMID: 27895171] (IHC-P, Primate - Macaca mulatta (Rhesus Macaque))	IHC-P	Primate - Macaca mulatta (Rhesus Macaque)
Shang L, Duan L, Perkey KE et al. Epithelium-innate immune cell axis in mucosal responses to SIV Mucosal Immunol 7/20/2016 [PMID: 27435105]
Kuang-Hui Sun TNF-? augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma J Cell Mol Med, 2016-06-14;0(0):. 2016-06-14 [PMID: 27297979] (Flow Cytometry, IHC-P, Western Blot, Human)	Flow Cytometry, IHC-P, Western Blot	Human
Karjalainen M, Ojaniemi M, Haapalainen A, Mahlman M, Salminen A, Huusko J, Maatta T, Kaukola T, Anttonen J, Ulvila J, Haataja R, Teramo K, Kingsmore S, Palotie A, Muglia L, Ramet M, Hallman M CXCR3 Polymorphism and Expression Associate with Spontaneous Preterm Birth. J Immunol, 2015-07-24;195(5):2187-98. 2015-07-24 [PMID: 26209629] (IHC-P, Western Blot, Human)	IHC-P, Western Blot	Human
Wightman S, Uppal A, Pitroda S, Ganai S, Burnette B, Stack M, Oshima G, Khan S, Huang X, Posner M, Weichselbaum R, Khodarev N Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome. Br J Cancer, 2015-06-04;113(2):327-35. 6/4/2015 [PMID: 26042934]
McCully M, Collins P, Hughes T, Thomas C, Billen J, O'Donnell V, Moser B Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. J Immunol, 2015-05-22;195(1):96-104. 2015-05-22 [PMID: 26002980] (Flow Cytometry, Human)	Flow Cytometry	Human
Byung Min Chung, Artem Arutyunov, Erika Ilagan, Nu Yao, Marsha Wills-Karp, Pierre A. Coulombe Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes Journal of Cell Biology 2015-03-02 [PMID: 25713416]
Zsiros E, Duttagupta P, Dangaj D, Li H, Frank R, Garrabrant T, Hagemann I, Levine B, June C, Zhang L, Wang E, Marincola F, Bedognetti D, Powell D, Tanyi J, Feldman M, Kandalaft L, Coukos G The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin Cancer Res, 2015-02-23;21(12):2840-50. 2015-02-23 [PMID: 25712684] (Neutralization, Human)	Neutralization	Human
Jennifer C. Barnes, Robert V. Lumsden, Julie Worrell, Ian P. Counihan, Sarah L. O’Beirne, John A. Belperio et al. CXCR3 Requirement for the Interleukin-13–Mediated Up-Regulation of Interleukin-13R alpha 2 in Pulmonary Fibroblasts American Journal of Respiratory Cell and Molecular Biology 2015-08-01 [PMID: 25514189]
Julie A Douthwaite, Sudharsan Sridharan, Catherine Huntington, Jayne Hammersley, Rose Marwood, Jonna K Hakulinen et al. Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1 mAbs 2015-01-02 [PMID: 25484051]
Serena Lunardi, Nigel B. Jamieson, Su Yin Lim, Kristin L. Griffiths, Manuela Carvalho-Gaspar, Osama Al-Assar et al. IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival Oncotarget 2014-11-30 [PMID: 25415223]
Rachel Wheat, Claudia Roberts, Tim Waterboer, Jane Steele, Jerry Marsden, Neil M. Steven et al. Inflammatory Cell Distribution in Primary Merkel Cell Carcinoma Cancers (Basel) 2014-05-06 [PMID: 24961933]
Falk M, Singh A, Faber C, Nissen M, Hviid T, Sorensen T Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci, 2014-05-08;55(7):4050-6. 2014-05-08 [PMID: 24812555] (Flow Cytometry, Human)	Flow Cytometry	Human
Carrega , Paolo, Bonaccorsi , Irene, Di Carlo , Emma, Morandi , Barbara, Paul , Petra, Rizzello , Valeria, Cipollone , Giuseppe, Navarra , Giuseppe, Mingari , Maria Cr, Moretta , Lorenzo, Ferlazzo , Guido CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph. J Immunol, 2014-03-19;192(8):3805-15. 2014-03-19 [PMID: 24646734] (Flow Cytometry, Human)	Flow Cytometry	Human
Bondar C, Araya R, Guzman L, Rua E, Chopita N, Chirdo F Role of CXCR3/CXCL10 axis in immune cell recruitment into the small intestine in celiac disease. PLoS ONE, 2014-02-20;9(2):e89068. 2014-02-20 [PMID: 24586509] (IHC, Human)	IHC	Human
Pinto S, Martinez-Romero A, O'Connor J, Gil-Benso R, San-Miguel T, Terradez L, Monteagudo C, Callaghan R Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation. BMC Cancer, 2014-02-22;14(0):118. 2014-02-22 [PMID: 24559071] (ICC, Human)	ICC	Human
Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, Corrias M, Moretta A, Bottino C Neuroblastoma-derived TGF-beta1 modulates the chemokine receptor repertoire of human resting NK cells. J Immunol, 2013-04-10;190(10):5321-8. 2013-04-10 [PMID: 23576682] (Flow Cytometry, Human)	Flow Cytometry	Human
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, Takeda K, Yamamoto M Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. Clin Cancer Res, 2013-03-11;19(8):2224-31. 2013-03-11 [PMID: 23479678] (Flow Cytometry, Human)	Flow Cytometry	Human
Chaturvedi , Pallavi, Gilkes , Daniele, Wong , Carmen C, Luo , Weibo, Zhang , Huafeng, Wei , Hong, Takano , Naoharu, Schito , Luana, Levchenko , Andre, Semenza , Gregg L Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Invest, 2012-12-17;123(1):189-205. 2012-12-17 [PMID: 23318994] (Western Blot, Human)	Western Blot	Human
Sela H, Goldman-Wohl D, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S Human trophectoderm apposition is regulated by interferon gamma-induced protein 10 (IP-10) during early implantation. Placenta, 2013-01-08;34(3):222-30. 2013-01-08 [PMID: 23306067] (IHC, Human)	IHC	Human
J Vinet, M van Zwam, I M Dijkstra, N Brouwer, H R J van Weering, A Watts et al. Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR British Journal of Pharmacology 2013-03-01 [PMID: 23121557]
Grant R Stenton, Lloyd F Mackenzie, Patrick Tam, Jennifer L Cross, Curtis Harwig, Jeffrey Raymond et al. Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo British Journal of Pharmacology 2013-03-01 [PMID: 23121445]
Linden A. Green, Daniela Petrusca, Gangaraju Rajashekhar, Tom Gianaris, Kelly S. Schweitzer, Liang Wang et al. Cigarette Smoke–Induced CXCR3 Receptor Up-Regulation Mediates Endothelial Apoptosis American Journal of Respiratory Cell and Molecular Biology 2012-12-01 [PMID: 22936405]
Canals M, Scholten DJ, de Munnik S, Han MK, Smit MJ, Leurs R Ubiquitination of CXCR7 controls receptor trafficking. PLoS ONE, 2012-03-23;7(3):e34192. 2012-03-23 [PMID: 22457824] (Bioassay, Human)	Bioassay	Human
Wu Q, Dhir R, Wells A Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion. Mol. Cancer, 2012-01-11;11(0):3. 2012-01-11 [PMID: 22236567] (Western Blot, Human)	Western Blot	Human
Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA Identification of human NK17/NK1 cells. PLoS ONE, 2011-10-21;6(10):e26780. 2011-10-21 [PMID: 22039549] (Flow Cytometry, Human)	Flow Cytometry	Human
D J Scholten, M Canals, M Wijtmans, S de Munnik, P Nguyen, D Verzijl et al. Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3 British Journal of Pharmacology 2012-06-01 [PMID: 21883151]
Gaetano Caramori, Lisa Lasagna, Angelo G. Casalini, Ian M. Adcock, Paolo Casolari, Marco Contoli et al. Immune Response to Mycobacterium tuberculosis Infection in the Parietal Pleura of Patients with Tuberculous Pleurisy PLoS ONE 2011-07-28 [PMID: 21829471]
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J. Immunol., 2010-02-17;184(6):2886-98. 2/17/2010 [PMID: 20164417]
Franciszkiewicz K, Le Floc'h A, Jalil A, Vigant F, Robert T, Vergnon I, Mackiewicz A, Benihoud K, Validire P, Chouaib S, Combadiere C, Mami-Chouaib F Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention. Cancer Res., 2009-07-28;69(15):6249-55. 2009-07-28 [PMID: 19638592] (Flow Cytometry, Human)	Flow Cytometry	Human
Busuttil A, Weigt SS, Keane MP, Xue YY, Palchevskiy V, Burdick MD, Huang C, Zisman DA, Fishbein M, Lynch JP, Strieter RM, Elashoff RM, Belperio JA CXCR3 ligands are augmented during the pathogenesis of pulmonary sarcoidosis. Eur. Respir. J., 2009-04-22;34(3):676-86. 2009-04-22 [PMID: 19386686] (IHC-P, Human)	IHC-P	Human
Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy. FASEB J., 2009-04-20;23(9):2928-41. 2009-04-20 [PMID: 19380511] (Functional Assay, Western Blot, Feline, Human)	Functional Assay, Western Blot	Feline, Human
Kim MJ, Romero R, Kim CJ, Tarca AL, Chhauy S, LaJeunesse C, Lee DC, Draghici S, Gotsch F, Kusanovic JP, Hassan SS, Kim JS Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. J. Immunol., 2009-03-15;182(6):3919-27. 2009-03-15 [PMID: 19265171] (IHC-Fr, Human)	IHC-Fr	Human
Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 2008-12-01;181(11):8053-67. 2008-12-01 [PMID: 19017998] (Flow Cytometry, ICC, IHC-P, Neutralization, Human)	Flow Cytometry, ICC, IHC-P, Neutralization	Human
Meiser A, Mueller A, Wise EL, McDonagh EM, Petit SJ, Saran N, Clark PC, Williams TJ, Pease JE The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor. J. Immunol., 2008-05-15;180(10):6713-24. 2008-05-15 [PMID: 18453591] (Flow Cytometry, Human)	Flow Cytometry	Human
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J. Immunol., 2007-09-15;179(6):4272-82. 2007-09-15 [PMID: 17785868] (ICC, Human)	ICC	Human
Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J. Immunol., 2007-09-15;179(6):3724-33. 2007-09-15 [PMID: 17785809] (Flow Cytometry, Human)	Flow Cytometry	Human
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 2006-06-16;120(2):220-31. 2006-06-16 [PMID: 16782408] (Neutralization, Human)	Neutralization	Human
Haas CS, Martinez RJ, Attia N, Haines GK, Campbell PL, Koch AE Chemokine receptor expression in rat adjuvant-induced arthritis. Arthritis Rheum., 2005-12-01;52(12):3718-30. 2005-12-01 [PMID: 16320322] (IHC, Rat)	IHC	Rat
Srivastava BI, Srivastava MD Establishment and characterization of SRIK-NKL: a novel CD8+ natural killer/T cell line derived from a patient with leukemic phase of acute lymphoblastic lymphoma. Leuk. Res., 2005-07-01;29(7):771-83. 2005-07-01 [PMID: 15927673] (ICC, Human)	ICC	Human
Lepej SZ, Rode OD, Jeren T, Vince A, Remenar A, Barsic B Increased expression of CXCR3 and CCR5 on memory CD4+ T-cells migrating into the cerebrospinal fluid of patients with neuroborreliosis: the role of CXCL10 and CXCL11. J. Neuroimmunol., 2005-04-19;163(1):128-34. 2005-04-19 [PMID: 15885315] (Flow Cytometry, Human)	Flow Cytometry	Human
Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 2005-05-01;52(5):1504-16. 2005-05-01 [PMID: 15880822] (IHC-Fr, Human)	IHC-Fr	Human
Suyama T, Furuya M, Nishiyama M, Kasuya Y, Kimura S, Ichikawa T, Ueda T, Nikaido T, Ito H, Ishikura H Up-regulation of the interferon gamma (IFN-gamma)-inducible chemokines IFN-inducible T-cell alpha chemoattractant and monokine induced by IFN-gamma and of their receptor CXC receptor 3 in human renal cell carcinoma. Cancer, 2005-01-15;103(2):258-67. 2005-01-15 [PMID: 15578685] (IHC-P, Human)	IHC-P	Human
Lim HW, Hillsamer P, Kim CH Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J. Clin. Invest., 2004-12-01;114(11):1640-9. 2004-12-01 [PMID: 15578096] (ICC, Human)	ICC	Human
van Marle G, Henry S, Todoruk T, Sullivan A, Silva C, Rourke SB, Holden J, McArthur JC, Gill MJ, Power C Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10. Virology, 2004-11-24;329(2):302-18. 2004-11-24 [PMID: 15518810] (ICC, IHC-P, Human)	ICC, IHC-P	Human
Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis. Int. J. Oncol., 2004-09-01;25(3):605-13. 2004-09-01 [PMID: 15289861] (ICC, Human)	ICC	Human
Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol., 2002-06-15;168(12):6244-52. 2002-06-15 [PMID: 12055238] (IHC-Fr, Human)	IHC-Fr	Human
Campbell J, Qin S, Unutmaz D, Soler D, Murphy K, Hodge M, Wu L, Butcher E Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol, 2001-06-01;166(11):6477-82. 2001-06-01 [PMID: 11359797] (Flow Cytometry, Human)	Flow Cytometry	Human
de Lavareille A, Roufosse F, Schandene L, Stordeur P, Cogan E, Goldman M Clonal Th2 cells associated with chronic hypereosinophilia: TARC-induced CCR4 down-regulation in vivo. Eur. J. Immunol., 2001-04-01;31(4):1037-46. 2001-04-01 [PMID: 11298328] (Flow Cytometry, Human)	Flow Cytometry	Human
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Gene Symbol	CXCR3
Uniprot	P49682()

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

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