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CCR3 Antibody (SR2050)

Images

 
Western Blot: CCR3 Antibody (SR2050) [NBP3-21677] - Western blot analysis using NBP3-21677 in K562 cell lysate.
Immunohistochemistry: CCR3 Antibody (SR2050) [NBP3-21677] - Immunohistochemical analysis of paraffin-embedded human epidemal cells of skin, using NBP3-21677.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
SR2050
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CCR3 Antibody (SR2050) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human CCR3 (Uniprot #: P51677)
Specificity
Detects endogenous levels of total CCR3
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CCR3
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CCR3 Antibody (SR2050)

  • b-chemokine receptor
  • CC chemokine receptor 3
  • C-C chemokine receptor type 3
  • C-C CKR-3
  • CCR3
  • CCR-3
  • CD193 antigen
  • CD193
  • chemokine (C-C motif) receptor 3
  • CKR3CC-CKR-3CMKBR3CD193
  • eosinophil CC chemokine receptor 3
  • Eosinophil eotaxin receptor
  • MGC102841

Background

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CCR3