AMPK alpha 2 Antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 7 of 7.

Publications using NB100-238	Applications	Species
Derkach K, Zakharova I, Zorina I et al. The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect PLoS ONE 2019-03-14 [PMID: 30870482] (WB, Mouse)	WB	Mouse
Roan, J N, Cheng, H N Et al. Exendin-4, a glucagon-like peptide-1 analogue, accelerates diabetic wound healing. J Surg Res 2017-02-01 [PMID: 27993221]
Oral mucosa harbors a high frequency of endothelial cells - a novel postnatal cell source for angiogenic regeneration Stem Cells Dev., 2016-12-22;0(0):. 2016-12-22 [PMID: 27832737]
Masuda M, Miyazaki-Anzai S, Keenan AL et al. Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity. J Clin Invest 2015-10-26 [PMID: 26517697]
Jaitovich A, Angulo M, Lecuona E et al. High CO2 levels cause skeletal muscle atrophy via AMPK, FoxO3a and muscle-specific ring finger protein1 (MuRF1). J Biol Chem. 2015-02-17 [PMID: 25691571] (WB, Mouse) Details: AMPK alpha 2 antibody used for WB application on total cell lysates as well as cytoplasmic fractions of C2C12 mouse myoblasts generated myotubes that were transfected with AMPK alpha 1 as well as AMPK alpha 2 siRNA followed by exposure to high CO2 (FIGURE 8C, 9B).	WB	Mouse
Gusarova GA, Dada LA, Kelly AM et al. {alpha}1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase C{zeta}. Mol Cell Biol 2009;29(13):3455-3464. [PMID: 19380482]
Rubin LJ, Magliola L, Feng X et al. Metabolic activation of AMP kinase in vascular smooth muscle. J Appl Physiol 2005-01-01 [PMID: 15377643]

Array NB100-238

• AMPK alpha 2 Antibodies
• AMPK alpha 2 Lysate
• AMPK alpha 2 Proteins