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TRPA1 Antibody

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Product Details

Summary
Reactivity DrSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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TRPA1 Antibody Summary

Immunogen
A synthetic peptide from aa region 1-50 of drosophila TRPA1 conjugated to an immunogenic carrier protein was used as the antigen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPA1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:300-1:2000
  • Immunohistochemistry-Frozen 1:300-1:2000
  • Immunohistochemistry-Paraffin 1:300-1:2000
  • Western Blot 1:300-1:2000
Theoretical MW
145 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized from whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.

Alternate Names for TRPA1 Antibody

  • ANKTM1
  • ANKTM1ankyrin-like with transmembrane domains 1
  • Ankyrin-like with transmembrane domains protein 1
  • Transformation-sensitive protein p120
  • transient receptor potential cation channel subfamily A member 1
  • transient receptor potential cation channel, subfamily A, member 1
  • TRPA1
  • Wasabi receptor

Background

TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds that include the cold-mimetic icilin and cannabinoids. TRPA1 is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. It is now known that TRPA1 protein is also widely expressed outside the CNS and is indeed dys-regulated during oncogenic transformation; TRPA1 associates with the tumor-suppressor protein CYLD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TRPA1 Antibody (NB100-98836). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in purchasing your Drosophila TRPA1 antibody (Catalog Number: NB100-98836). What is the peptide sequence that this antibody is specific to?
    • The antibody was raised against a peptide found in the first 50 amino acids of the Drosophila TRPA1 protein sequence. I hope this answers your question.

Secondary Antibodies

 

Isotype Controls

Additional TRPA1 Products

Research Areas for TRPA1 Antibody (NB100-98836)

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Blogs on TRPA1.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

TRPA1: A contributor to itching and inflammation? Scratch that!
Transient receptor potential A1 (TRPA1) is an ion channel found on the plasma membrane of many cell types that functions in diverse sensory processes such as pain and temperature. The TRPA1 ion channel is specifically expressed in nociceptive neurons,...  Read full blog post.

Touch Infographic: From Touch Receptors to the Brain
The body contains thousands of receptors and nerves which allow us to experience the sense of touch, also referred to as tactile perception. The somatosensory system allows organisms to perceive and decode a wide range of tactile stimuli to allow for ...  Read full blog post.

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Bioinformatics

Gene Symbol TRPA1