Vanilloid R1/TRPV1 Antibody - BSA Free

Manufactured by Genomic Antibody Technology™. GAT FAQs

TRPV1, a ligand-gated cation channel expressed in peripheral nociceptors, induces pain when activated by capsaicin. TRPV1 affects the inhibitory control of neurons by integrating multiple noxious signals, which is critical in chronic pain. Blocking TRPV1 is becoming a more common approach to suppression of pathological pain. When inflammation is present, TRPV1 causes an itch response. Dietary salt content can affect the concentration and activity of TRPV1, which in turn can affect kidney activities resulting in renin regulation. TRPV1 is also critically involved in thermal activation and detection of infrared radiation. Finally, TRPV1 is dysfunctional in hypertrophic hearts.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Marmoset, Primate.

We have publications tested in 5 applications: IF/IHC, IHC, IHC-Fr, IHC-P, WB.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using NBP1-71774	Applications	Species
Kumar V, Kingsley D, Madhurakkat Perikamana S et al. Self-assembled innervated vasculature-on-a-chip to study nociception Biofabrication 2023-04-13 [PMID: 36996841] (WB)	WB
Hovhannisyan AH, Lindquist KA, Belugin S et al. Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets bioRxiv : the preprint server for biology 2023-02-12 [PMID: 36798270] (IHC-Fr, Marmoset, Primate) Details: Dilution used in IHC-Fr 1:200	IHC-Fr	Marmoset, Primate
Ilhan HD, Unal B, Ayaz Y, Erin N Changes in TRPV1 Expression as Well as Substance P and Vasoactive Intestinal Peptide Levels Are Associated with Recurrence of Pterygium International journal of molecular sciences 2022-12-10 [PMID: 36555331] (IHC-P, Human) Details: Dilution used in IHC-P 1:100	IHC-P	Human
Samivel R, Kim DW, Son HR et al. The role of TRPV1 in the CD4+ T cell-mediated inflammatory response of allergic rhinitis. Oncotarget. 2016-01-05 [PMID: 26700618] (IF/IHC, Human, Mouse)	IF/IHC	Human, Mouse
Tram M, Ibrahim T, Hovhannisyan A et al. Lingual innervation in male and female marmosets Neurobiology of Pain 2023-08-01 (IHC-Fr, Primate) Details: Species-marmoset (Callithrix jacchus)	IHC-Fr	Primate
Warfield R, Robinson JA, Podgorski RM et al. Neuroinflammation in the Dorsal Root Ganglia and Dorsal Horn Contributes to Persistence of Nociceptor Sensitization in SIV-Infected Antiretroviral Therapy-Treated Macaques The American journal of pathology 2023-09-19 [PMID: 37734588] (IHC)	IHC
Moutafidi A, Gatzounis G, Zolota V, Assimakopoulou M Heat shock factor 1 in brain tumors: a link with transient receptor potential channels TRPV1 and TRPA1 Journal of molecular histology 2021-09-30 [PMID: 34591198]
Bi X, Xu Y, Li T et al. Chronic stress augments esophageal inflammation, and alters the expression of transient receptor potential vanilloid 1 and protease-activated receptor 2 in a murine model Mol Med Rep 2019-06-01 [PMID: 31059059]
Rizopoulos T, Papadaki-Petrou H, Assimakopoulou M. Expression Profiling of the Transient Receptor Potential Vanilloid (TRPV) Channels 1, 2, 3 and 4 in Mucosal Epithelium of Human Ulcerative Colitis. Cells. 2018-06-15 [PMID: 29914124] (IHC-P, Human)	IHC-P	Human
Assimakopoulou M, Pagoulatos D, Nterma P, Pharmakakis N. Immunolocalization of cannabinoid receptor type 1 and CB2 cannabinoid receptors, and transient receptor potential vanilloid channels in pterygium Mol Med Rep 2017-08-14 [PMID: 28849159] (Human)		Human
Hidaka T, Ogawa E, Kobayashi EH et al. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nat. Immunol. 2016-11-21 [PMID: 27869817] (Mouse) Details: This citation used the DyLight 488 version of this antibody.		Mouse
Show All 11 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Feng Li	IHC-P	Human	01/23/2019	View Summary Application Immunohistochemistry-Paraffin Sample Tested Stomach tissue Species Human Lot A-4

Array NBP1-71774

• Vanilloid R1/TRPV1 Antibodies
• Vanilloid R1/TRPV1 Lysates
• Vanilloid R1/TRPV1 Proteins