TLR7 Antibody (533707) [PerCP (Peridinin-chlorophyll Protein Complex)]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Toll-like receptor 7 (TLR7) is a 120 kDa (predicted, unglycosylated) type I transmembrane glycoprotein and member of the Toll-like receptor family. Human TLR7 is synthesized as a 1049 amino acid (aa) precursor that contains a 26 aa signal sequence, an 803 aa extracellular domain (ECD), a 21 aa transmembrane sequence, and a 189 aa cytoplasmic domain. Mature human TLR7 is 81% aa identical to mature mouse TLR7. TLR7 is detected in brain, placenta, spleen, stomach, small intestine, lung, and in plasmacytoid pre-dendritic cells. Functionally, TLR7 participates in the innate immune response to microbial agents.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 2 of 2.

Publications using IC5875C	Applications	Species
L Chen, R Chen, M Yao, Z Feng, G Yuan, F Ye, K Nguyen, J Karn, GA McComsey, TM McIntyre, G Jin COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells Scientific Reports, 2022-12-16;12(1):21779. 2022-12-16 [PMID: 36526691] (Flow Cytometry, Human)	Flow Cytometry	Human
Giugliano S, Petroff M, Warren B, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko M, Gale M, Golden-Mason L, Winn V, Rosen H Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. J Immunol, 2015-09-04;195(8):3737-47. 2015-09-04 [PMID: 26342030] (Flow Cytometry, Human)	Flow Cytometry	Human

Array IC5875C

• TLR7 Antibodies
• TLR7 Antibody Pack
• TLR7 ELISA Kit
• TLR7 Proteins
• TLR7 Proteins and Enzymes