Name: TGF-beta RII Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF532
Price: 489 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	MuSpecies Glossary
Applications	WB, Flow, CyTOF-ready
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 700 FAB532N-100

Alexa Fluor 700 FAB532N-025

Allophycocyanin FAB532A-100

Allophycocyanin FAB532A-025

Biotin BAF532

Fluorescein FAB532F-100

Fluorescein FAB532F-025

Phycoerythrin FAB532P-100UG

Phycoerythrin FAB532P-025UG

Catalog# & Formulation	Size	Price
Carrier Free FAB532F-100

Carrier Free FAB532A-100

Carrier Free FAB532N-100

Carrier Free FAB532A-025

Carrier Free FAB532F-025

Carrier Free FAB532N-025

Carrier Free AF532-SP

Carrier Free FAB532P-100UG

Carrier Free FAB532P-025UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 700	FAB532N-100
Alexa Fluor 700	FAB532N-025
Allophycocyanin	FAB532A-100
Allophycocyanin	FAB532A-025
Biotin	BAF532
Fluorescein	FAB532F-100
Fluorescein	FAB532F-025
Phycoerythrin	FAB532P-100UG
Phycoerythrin	FAB532P-025UG

TGF-beta RII Antibody [Unconjugated]

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TGF-beta RII Antibody [Unconjugated] Summary

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Alternate Names for TGF-beta RII Antibody [Unconjugated]

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Publications for TGF-beta RII Antibody (AF532)(12)

Reviews for TGF-beta RII Antibody (AF532) (0)

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Bioinformatics

Immunogen	Mouse myeloma cell line NS0-derived recombinant mouse TGF‑ beta RII and S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF‑ beta RII Ile24-Asp184 Accession # Q62312
Specificity	Detects mouse TGF-beta RII in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) TGF-beta RII is observed.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	TGFBR2
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Publications using AF532	Applications	Species
Zahraeifard, S;Xiao, Z;So, JY;Ahad, A;Montoya, S;Park, WY;Sornapudi, T;Andohkow, T;Read, A;Kedei, N;Koparde, V;Yang, H;Lee, M;Wong, N;Cam, M;Wang, K;Ruppin, E;Luo, J;Hollander, C;Yang, L; Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression Nature communications 2024-07-12 [PMID: 38997291] (Western Blot, Mouse)	Western Blot	Mouse
JL Lee, SC Fra-Bido, AR Burton, S Innocentin, DL Hill, MA Linterman B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction Aging Cell, 2022-08-18;0(0):e13692. 8/18/2022 [PMID: 35980826]
Rivellese F, Surace AEA, Goldmann K Et al. Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial Nat Med 5/19/2022 [PMID: 35589854] Details: Citation using the Alexa Fluor 532 version of this antibody.
Wanner N, Barnhart J, Apostolakis N Et al. Using the Autofluorescence Finder on the Sony ID7000(TM) Spectral Cell Analyzer to Identify and Unmix Multiple Highly Autofluorescent Murine Lung Populations Front Bioeng Biotechnol 4/4/2022 [PMID: 35372303] Details: Citation using the Alexa Fluor 532 version of this antibody.
Tereza Andreou, Jennifer Williams, Rebecca J Brownlie, Robert J Salmond, Erica Watson, Gary Shaw et al. Hematopoietic stem cell gene therapy targeting TGF beta enhances the efficacy of irradiation therapy in a preclinical glioblastoma model Journal for ImmunoTherapy of Cancer 2021-03-11 [PMID: 33707311]
K Nolan, G Verzosa, T Cleaver, D Tippimanch, LN DePledge, XJ Wang, C Young, A Le, R Doebele, H Li, SP Malkoski Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models Cancer Cell Int., 2020-08-28;20(0):417. 2020-08-28 [PMID: 32874131] (Western Blot, Mouse)	Western Blot	Mouse
J Lam, M van den Bo, J Wegrzyn, J Parker, R Ibrahim, K Slowski, L Chang, S Martinez-H, G Condorelli, M Boldin, Y Deng, P Umlandt, M Fuller, A Karsan miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGF? signaling Nat Commun, 2018-06-20;9(1):2418. 2018-06-20 [PMID: 29925839] (Western Blot, Mouse)	Western Blot	Mouse
Yuan CL, Liang R, Liu ZH et al. Bone morphogenetic protein and activin membrane-bound inhibitor overexpression inhibits gastric tumor cell invasion via the transforming growth factor-B/epithelial-mesenchymal transition signaling pathway Exp Ther Med 6/1/2018 [PMID: 29805551]
miR-17?92 family clusters control iNKT cell ontogenesis via modulation of TGF-? signaling Proc. Natl. Acad. Sci. U.S.A, 2016-12-05;0(0):. 2016-12-05 [PMID: 27930306] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, Lu Y, Zhang Z, Liu H, Wang X, Wang R, Chu Y, Yang R Dendritic cell SIRT1-HIF1alpha axis programs the differentiation of CD4+ T cells through IL-12 and TGF-beta1. Proc Natl Acad Sci U S A, 2015-02-17;112(9):E957-65. 2015-02-17 [PMID: 25730867] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Bhadra R, Moretto M, Castillo J, Petrovas C, Ferrando-Martinez S, Shokal U, Leal M, Koup R, Eleftherianos I, Khan I Intrinsic TGF-beta signaling promotes age-dependent CD8+ T cell polyfunctionality attrition. J Clin Invest, 2014-04-24;124(6):2441-55. 2014-04-24 [PMID: 24762437] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Goto Y, Manabe N, Uchio-Yamada K, Yamaguchi-Yamada M, Inoue N, Yamamoto Y, Ogura A, Nagano N, Miyamoto H Augmented cytoplasmic Smad4 induces acceleration of TGF-beta1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation. Cell Tissue Res., 2003-11-13;315(2):209-21. 2003-11-13 [PMID: 14615933] (ICC, Mouse)	ICC	Mouse
Show All 12 Publications. Collapse Publications.

Gene Symbol	TGFBR2
Uniprot	Q62312()