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Recombinant Human TGF-beta 3 Protein

Name: Recombinant Human TGF-beta 3 Protein
Brand: Novus Biologicals
SKU: 243-B3
Price: 416 USD

(120 Publications)

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As an alternative, please consider our next generation CHO-drived Recombinant Human TGF‑ beta 3 (8420-B3). It has equivalent bioactivity to Sf 21 (baculovirus)-derived Recombinant Human TGF‑ beta 3 (Catalog # ...read more

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	Bioactivity

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Catalog# & Formulation	Size	Price
Carrier Free 243-B3-002/CF

Carrier Free 243-B3-010/CF

Carrier Free 243-B3-200/CF

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Recombinant Human TGF-beta 3 Protein Summary

Details of Functionality	Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389. The ED₅₀ for this effect is 0.0100-0.0400 ng/mL.
Source	Spodoptera frugiperda, Sf 21 (baculovirus)-derived human TGF-beta 3 protein Ala301-Ser412 (Tyr340Phe)
Accession #	P10600
N-terminal Sequence	Ala301
Structure / Form	Disulfide-linked homodimer
Protein/Peptide Type	Recombinant Proteins
Gene	TGFB3
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Note	<0.01 EU per 1 μg of the protein by the LAL method.

Applications/Dilutions

Dilutions

Bioactivity

Theoretical MW

12.7 kDa (monomer).
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

SDS-PAGE

12 kDa, reducing conditions
24 kDa, non-reducing conditions

Publications

Read Publications using
243-B3 in the following applications:

Bioassay
100 publications
Cell Culture
8 publications
Differentiation
4 publications
ELISA (Standard)
2 publications
ICC
1 publication
In Vivo
4 publications
In vitro
1 publication
Surface Plasmon Resonance
1 publication
Western Blot
1 publication

Packaging, Storage & Formulations

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution Instructions	Reconstitute at 20 μg/mL in sterile 4 mM HCl containing 1 mg/mL human or bovine serum albumin.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human TGF-beta 3 Protein

ARVD
ARVD1
FLJ16571
LDS5
RNHF
TGFB3
TGFbeta 3
TGF-beta 3
TGF-beta3
TGF-beta-3
transforming growth factor beta-3
transforming growth factor, beta 3

Background

TGF beta 3 (transforming growth factor-beta 3) is a member of a TGF-beta superfamily subgroup that is defined by their structural and functional similarities (1-5). TGF-beta 3 and its closely related proteins, TGF-beta 1 and -beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-mesenchymal transition (4, 6, 7). The non-redundant biological effects of TGF-beta 3 include involvement in palatogenesis, chondrogenesis, and pulmonary development (1, 2, 7-9). Human TGF- beta 3 cDNA encodes a 412 amino acid (aa) precursor that contains a 20 aa signal peptide and a 392 aa proprotein. The proprotein is processed by a furinlike convertase to generate a 220 aa latencyassociated peptide (LAP) and a 112 aa mature TGF-beta 3 (10, 11). Mature human TGF-beta 3 shows 100%, 99%, and 98% aa identity with mouse/dog/horse, rat, and pig TGF- beta 3, respectively. TGF-beta 3 is secreted as a complex with LAP. This latent form of TGF-beta 3 becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin-1, and a subset of integrins (12). TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF- beta RI or ALK-1, to modulate transcription through Smad phosphorylation (13-15). The divergent biological effects exerted by individual TGF-beta isoforms is dependent upon the recruitment of co-receptors (TGF- beta RIII and endoglin) and the subsequent initiation of Smad-dependent or -independent signaling pathways (14, 16, 17).

Barrio, M.C. et al. (2014) Cells Tissues Organs. [Epub ahead of print; PMID 24861080].
Doetschman, T. et al. (2012) Genesis 50:59.
Mittl, P.R. et al. (1996) Protein Sci. 5:1261.
Sporn, M.B. (2006) Cytokine Growth Factor Rev. 17:3.
Wahl, S.M. et al. (2006) Immunol. Rev. 213:213.
Chang, H. et al. (2002) Endocr. Rev. 23:787.
Dunker, N. and K. Krieglstein (2000) Eur. J. Biochem. 267:6982.
Jin, J.Z. et al. (2014) Dev. Dyn. [Epub ahead of print; PMID 25104574].
Tang, Q.O. et al. (2009) Expert Opin. Biol Ther. 9:689.
Derynck, R. et al. (1988) EMBO J. 7:3737.
Miyazono, K. et al. (1988) J. Biol. Chem. 263:6407.
Oklu, R. and R. Hesketh (2000) Biochem. J. 352 Pt 3:601.
Cui, X.M. and C.F. Shuler (2000) Int. J. Dev. Biol. 44:397.
de Caestecker, M. (2004) Cytokine Growth Factor Rev. 15:1.
Nakajima, A. et al. (2007) Dev. Dyn. 236:791.
Iwata, J. et al. (2012) J. Clin. Invest. 122:873.
Gatza, C.E. et al. (2010) Cell. Signal. 22:1163.

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Publications for TGF-beta 3 (243-B3)(120)

We have publications tested in 13 confirmed species: Human, Mouse, Rat, Bovine, Canine, Drosophila melanogaster, Equine, Horse, Ovine, Primate - Macaca mulatta (Rhesus Macaque), Primate - Rhesus macaque, Rabbit, Xenopus.

We have publications tested in 9 applications: Bioassay, Cell Culture, Differentiation, ELISA (Standard), ICC, In Vivo, In vitro, Surface Plasmon Resonance, Western Blot.

Showing Publications 1 - 10 of 120. Show All 120 Publications.

Publications using 243-B3	Applications	Species
Ely, EV;Kapinski, AT;Paradi, SG;Tang, R;Guilak, F;Collins, KH; Designer Fat Cells: Adipogenic Differentiation of CRISPR-Cas9 Genome-Engineered Induced Pluripotent Stem Cells bioRxiv : the preprint server for biology 2023-10-26 [PMID: 37961399] (Bioassay, Mouse)	Bioassay	Mouse
Aouimeur, I;Sagnial, T;Coulomb, L;Maurin, C;Thomas, J;Forestier, P;Ninotta, S;Perrache, C;Forest, F;Gain, P;Thuret, G;He, Z; Investigating the Role of TGF-? Signaling Pathways in Human Corneal Endothelial Cell Primary Culture Cells 2023-06-14 [PMID: 37371094] (ICC, Human)	ICC	Human
Z You, L Wang, H He, Z Wu, X Zhang, S Xue, P Xu, Y Hong, M Xiong, W Wei, Y Chen Mapping of clonal lineages across developmental stages in human neural differentiation Cell Stem Cell, 2023-03-17;0(0):. 2023-03-17 [PMID: 36933556] (Bioassay, Human)	Bioassay	Human
Z You, L Wang, H He, Z Wu, X Zhang, S Xue, P Xu, Y Hong, M Xiong, W Wei, Y Chen Mapping of clonal lineages across developmental stages in human neural differentiation Cell Stem Cell, 2023;0(0):. 2023 [PMID: 36933556] (Bioassay, Human)	Bioassay	Human
AR Dicks, GI Maksaev, Z Harissa, A Savadipour, R Tang, N Steward, W Liedtke, CG Nichols, CL Wu, F Guilak Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes Elife, 2023-02-22;12(0):. 2023-02-22 [PMID: 36810131] (Bioassay, Human)	Bioassay	Human
K Santerre, S Cortez Ghi, S Proulx TGF-beta-Mediated Modulation of Cell-Cell Interactions in Postconfluent Maturing Corneal Endothelial Cells Investigative Ophthalmology & Visual Science, 2022-10-03;63(11):3. 2022-10-03 [PMID: 36194422] (Bioassay, Human)	Bioassay	Human
I Hanson, KE Pitman, U Altanerova, ? Altaner, E Malinen, NFJ Edin Low-Dose-Rate Radiation-Induced Secretion of TGF-beta3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding International Journal of Molecular Sciences, 2022-07-24;23(15):. 2022-07-24 [PMID: 35897723] (Bioassay, Human)	Bioassay	Human
L Wang, G Lin, Z Zuo, Y Li, SK Byeon, A Pandey, HJ Bellen Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia Oncogene, 2022-07-13;8(28):eabn3326. 2022-07-13 [PMID: 35857503] (Bioassay, Drosophila melanogaster)	Bioassay	Drosophila melanogaster
J Kim, J Jeon, B Song, N Lee, S Ko, Y Cha, P Leblanc, H Seo, KS Kim Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells Nature Protocols, 2022-02-09;0(0):. 2022-02-09 [PMID: 35140411] (Bioassay, Human)	Bioassay	Human
M Melzer, S Schubert, SF Müller, J Geyer, A Hagen, S Niebert, J Burk Rho/ROCK Inhibition Promotes TGF-beta3-Induced Tenogenic Differentiation in Mesenchymal Stromal Cells Stem Cells International, 2021-10-08;2021(0):8284690. 2021-10-08 [PMID: 34659420] (Bioassay, Human)	Bioassay	Human
V Padmanabha, H Liu, G Ciceri, J Jungverdor, G Frishman, J Tchieu, GY Cederquist, I Rothenaign, K Schorpp, L Klepper, RM Walsh, TW Kim, D Cornacchia, A Ruepp, J Mayer, K Hadian, D Frishman, L Studer, M Vincendeau Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3 Cell Stem Cell, 2021-05-04;0(0):. 2021-05-04 [PMID: 33951478] (Bioassay, Human)	Bioassay	Human
Y Ikeda-Iwab, Y Taniyama, N Katsuragi, F Sanada, N Koibuchi, K Shibata, K Shimazu, H Rakugi, R Morishita Periostin Short Fragment with Exon 17 via Aberrant Alternative Splicing Is Required for Breast Cancer Growth and Metastasis Cells, 2021-04-14;10(4):. 2021-04-14 [PMID: 33919736] (Bioassay, Human)	Bioassay	Human
HN Kim, JY Shin, DY Kim, JE Lee, PH Lee Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models Journal of tissue engineering, 2021-03-30;12(0):2041731421100. 2021-03-30 [PMID: 33854750] (Differentiation, Differentiation, Mouse)	Differentiation, Differentiation	Mouse
N Franceschi, B Verbruggen, MA Tryfonidou, AB Kruisselbr, H Baelde, KE de Visser, K Szuhai, AM Cleton-Jan, JVMG Bovée Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics Cancers, 2021-03-05;13(5):. 2021-03-05 [PMID: 33807947] (Bioassay, Canine, Mouse)	Bioassay	Canine, Mouse
Y Tao, SC Vermilyea, M Zammit, J Lu, M Olsen, JM Metzger, L Yao, Y Chen, S Phillips, JE Holden, V Bondarenko, WF Block, TE Barnhart, N Schultz-Da, K Brunner, H Simmons, BT Christian, ME Emborg, SC Zhang Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys Nature Medicine, 2021-03-01;0(0):. 2021-03-01 [PMID: 33649496] (Bioassay, Primate - Rhesus macaque)	Bioassay	Primate - Rhesus macaque
KJG Kenswil, P Pisterzi, G Sánchez-Du, C van Dijk, A Lolli, C Knuth, B Vanchin, AC Jaramillo, RM Hoogenboez, MA Sanders, J Feyen, T Cupedo, IG Costa, R Li, EMJ Bindels, K Lodder, B Blom, PK Bos, MJ Goumans, P Ten Dijke, E Farrell, G Krenning, MHGP Raaijmaker Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation Cell Stem Cell, 2021-02-08;0(0):. 2021-02-08 [PMID: 33561425] (Bioassay, Human)	Bioassay	Human
TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel, ND Socci, SJ Choi, S Zabierowsk, BN Dubose, EJ Hill, EV Mosharov, S Irion, MJ Tomishima, V Tabar, L Studer Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use Cell Stem Cell, 2021-02-04;28(2):343-355.e5. 2021-02-04 [PMID: 33545081] (Bioassay, Human)	Bioassay	Human
S Nürnberger, C Schneider, C Keibl, B Schädl, P Heimel, X Monforte, AH Teuschl, M Nalbach, PJ Thurner, J Grillari, H Redl, S Wolbank Repopulation of decellularised articular cartilage by laser-based matrix engraving EBioMedicine, 2021-01-19;0(0):103196. 2021-01-19 [PMID: 33483297] (Bioassay, Human)	Bioassay	Human
T Otsuka, PY Mengsteab, CT Laurencin Control of mesenchymal cell fate via application of FGF-8b in vitro Stem Cell Research, 2021-01-07;51(0):102155. 2021-01-07 [PMID: 33445073] (Bioassay, Rat)	Bioassay	Rat
CL Wu, A Dicks, N Steward, R Tang, DB Katz, YR Choi, F Guilak Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis Nature Communications, 2021-01-13;12(1):362. 2021-01-13 [PMID: 33441552] (Bioassay, Human)	Bioassay	Human
L Chen, K Shi, W Qiu, L Aagaard, M Kassem Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation Stem Cells International, 2020-08-19;2020(0):8857344. 2020-08-19 [PMID: 32922451] (Bioassay, Human)	Bioassay	Human
YH Kim, GY Park, N Rabinovitc, S Tarafder, CH Lee Effect of local anesthetics on viability and differentiation of various adult stem/progenitor cells Stem Cell Res Ther, 2020-09-07;11(1):385. 2020-09-07 [PMID: 32894184] (Cell Culture, Human)	Cell Culture	Human
JW Kim, X Yin, A Jhaldiyal, MR Khan, I Martin, Z Xie, T Perez-Rose, M Kumar, L Abalde-Atr, J Xu, L Chen, SM Eacker, DJ Surmeier, NT Ingolia, TM Dawson, VL Dawson Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis Cell Stem Cell, 2020-08-25;27(4):633-645.e7. 2020-08-25 [PMID: 32846140] (Bioassay, Human)	Bioassay	Human
SK Meurer, O Tezcan, T Lammers, R Weiskirche Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells Cell. Signal., 2020-08-03;74(0):109731. 2020-08-03 [PMID: 32758668] (Bioassay, Human)	Bioassay	Human
L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020-06-19;27(1):125-136.e7. 2020-06-19 [PMID: 32579880] (Bioassay, Human)	Bioassay	Human
L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020;27(1):125-136.e7. 2020 [PMID: 32579880] (Bioassay, Human)	Bioassay	Human
L Bundgaard, A Stensballe, KJ Elbæk, LC Berg Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells to assess the effect of chondrogenic differentiation on response to interleukin-1&beta treatment Stem Cell Res Ther, 2020-05-20;11(1):187. 2020-05-20 [PMID: 32434555] (Cell Culture, Horse)	Cell Culture	Horse
I Rajpar, JG Barrett Multi-differentiation potential is necessary for optimal tenogenesis of tendon stem cells Stem Cell Res Ther, 2020-04-09;11(1):152. 2020-04-09 [PMID: 32272975] (Bioassay, Horse)	Bioassay	Horse
A Dicks, CL Wu, N Steward, SS Adkar, CA Gersbach, F Guilak Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter Stem Cell Res Ther, 2020-02-18;11(1):66. 2020-02-18 [PMID: 32070421] (Cell Culture, Human)	Cell Culture	Human
Y Wu, K Chen, G Xing, L Li, B Ma, Z Hu, L Duan, X Liu Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition Sci Adv, 2019-11-27;5(11):eaax7525. 2019-11-27 [PMID: 31807705] (Cell Culture, Mouse)	Cell Culture	Mouse
S Mahajani, A Raina, C Fokken, S Kügler, M Bähr Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors Cell Death Dis, 2019-11-27;10(12):898. 2019-11-27 [PMID: 31776327] (Cell Culture, Human)	Cell Culture	Human
D Leitner, M Ramamoorth, M Dejosez, TP Zwaka Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation Stem Cell Res, 2019-10-24;41(0):101617. 2019-10-24 [PMID: 31731178] (Cell Culture, In vitro, Human, Mouse)	Cell Culture, In vitro	Human, Mouse
J Lovecchio, P Gargiulo, JL Vargas Lun, E Giordano, ÓE Sigurjónss A standalone bioreactor system to deliver compressive load under perfusion flow to hBMSC-seeded 3D chitosan-graphene templates Sci Rep, 2019-11-14;9(1):16854. 2019-11-14 [PMID: 31728040] (Cell Culture, Human)	Cell Culture	Human
O Daniels, J Frisch, JK Venkatesan, A Rey-Rico, G Schmitt, M Cucchiarin Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment J Clin Med, 2019-10-07;8(10):. 2019-10-07 [PMID: 31591319] (Bioassay, Human)	Bioassay	Human
HC O'Neill, HK Lim, P Periasamy, L Kumarappan, JKH Tan, TJ O'Neill Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis PLoS ONE, 2019-10-04;14(10):e0223416. 2019-10-04 [PMID: 31584977] (Bioassay, Mouse)	Bioassay	Mouse
M Riessland, B Kolisnyk, TW Kim, J Cheng, J Ni, JA Pearson, EJ Park, K Dam, D Acehan, LS Ramos-Espi, W Wang, J Zhang, JW Shim, G Ciceri, L Brichta, L Studer, P Greengard Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons Cell Stem Cell, 2019-09-19;25(4):514-530.e8. 2019-09-19 [PMID: 31543366] (Bioassay, Human)	Bioassay	Human
Y Kawakami, WS Hambright, K Takayama, X Mu, A Lu, JH Cummins, T Matsumoto, T Yurube, R Kuroda, M Kurosaka, FH Fu, PD Robbins, LJ Niedernhof, J Huard Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice Mol Ther Methods Clin Dev, 2019-05-30;14(0):64-76. 2019-05-30 [PMID: 31312666] (Bioassay, Mouse)	Bioassay	Mouse
A Shojaee, A Parham, F Ejeian, MH Nasr Esfah Equine adipose mesenchymal stem cells (eq-ASCs) appear to have higher potential for migration and musculoskeletal differentiation Res. Vet. Sci., 2019-07-03;125(0):235-243. 2019-07-03 [PMID: 31310927] (Bioassay, Equine, Human)	Bioassay	Equine, Human
X Wu, M Ma, P Wang, Z Xie, S Wang, H Su, W Deng, P Feng, C Su, J Yang, J Li, S Tang, Y Wu, H Shen ?2-HS Glycoprotein in Plasma Extracellular Vesicles Inhibits the Osteogenic Differentiation of Human Mesenchymal Stromal Cells In Vitro Stem Cells Int, 2019-02-07;2019(0):7246479. 2019-02-07 [PMID: 30881463] (Bioassay, Human)	Bioassay	Human
A Wehrle, TM Witkos, S Unger, J Schneider, JA Follit, J Hermann, T Welting, V Fano, M Hietala, N Vatanavich, K Schoner, J Spranger, M Schmidts, B Zabel, GJ Pazour, A Bloch-Zupa, G Nishimura, A Superti-Fu, M Lowe, E Lausch Hypomorphic mutations of TRIP11 cause odontochondrodysplasia JCI Insight, 2019-02-07;4(3):. 2019-02-07 [PMID: 30728324] (Bioassay, Human)	Bioassay	Human
J Lee, SJ Kwon, JH Kim, H Jang, NK Lee, JW Hwang, JH Kim, JW Chang, DL Na Cerebrospinal fluid from Alzheimer's disease patients as an optimal formulation for therapeutic application of mesenchymal stem cells in Alzheimer's disease Sci Rep, 2019-01-24;9(1):564. 2019-01-24 [PMID: 30679696] (Bioassay, Human)	Bioassay	Human
TS Fu, YH Wei, PY Cheng, IM Chu, WC Chen A Novel Biodegradable and Thermosensitive Poly(Ester-Amide) Hydrogel for Cartilage Tissue Engineering Biomed Res Int, 2018-12-19;2018(0):2710892. 2018-12-19 [PMID: 30662902] (Bioassay, Rabbit)	Bioassay	Rabbit
M Kim, DR Steinberg, JA Burdick, RL Mauck Extracellular vesicles mediate improved functional outcomes in engineered cartilage produced from MSC/chondrocyte cocultures Proc. Natl. Acad. Sci. U.S.A., 2019-01-15;116(5):1569-1578. 2019-01-15 [PMID: 30647113] (Bioassay, Bovine)	Bioassay	Bovine
JS Park, M Kim, NJ Song, JH Kim, D Seo, JH Lee, SM Jung, JY Lee, J Lee, YS Lee, KW Park, SH Park A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells Stem Cells, 2018-12-07;0(0):. 2018-12-07 [PMID: 30444564] (Bioassay, Mouse)	Bioassay	Mouse
KA de Lima, PB Donate, J Talbot, M Davoli-Fer, RS Peres, TM Cunha, JC Alves-Filh, FQ Cunha TGF?1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism Cell Death Dis, 2018-11-13;9(11):1130. 2018-11-13 [PMID: 30425241] (Bioassay, Mouse)	Bioassay	Mouse
SS Adkar, CL Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, F Guilak Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing Stem Cells, 2018-10-31;0(0):. 2018-10-31 [PMID: 30378731] (Bioassay, Human)	Bioassay	Human
J Riegger, HG Palm, RE Brenner The functional role of chondrogenic stem/progenitor cells: novel evidence for immunomodulatory properties and regenerative potential after cartilage injury Eur Cell Mater, 2018-09-14;36(0):110-127. 2018-09-14 [PMID: 30215457] (Bioassay, Human)	Bioassay	Human
H Lin, E Hay, A Latourte, T Funck-Bren, W Bouaziz, HK Ea, AM Khatib, P Richette, M Cohen-Sola Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGF?-dependent manner and limits osteoarthritis in mice Sci Rep, 2018-07-11;8(1):10488. 2018-07-11 [PMID: 29992982] (Bioassay, Mouse)	Bioassay	Mouse
G Collo, L Cavalleri, M Zoli, U Maskos, E Ratti, E Merlo Pich Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons Front Pharmacol, 2018-06-01;9(0):572. 2018-06-01 [PMID: 29910731] (Bioassay, Human)	Bioassay	Human
MM Adil, DV Schaffer hPSC-derived Midbrain Dopaminergic Neurons Generated in a Scalable 3-D Biomaterial Curr Protoc Stem Cell Biol, 2018-02-28;44(0):2D.21.1-2D.21. 2018-02-28 [PMID: 29512105] (Bioassay, Human)	Bioassay	Human
H Jing, B Gao, M Gao, H Yin, X Mo, X Zhang, K Luo, B Feng, W Fu, J Wang, W Zhang, M Yin, Z Zhu, X He, J Zheng Restoring tracheal defects in a rabbit model with tissue engineered patches based on TGF-?3-encapsulating electrospun poly(l-lactic acid-co-?-caprolactone)/collagen scaffolds Artif Cells Nanomed Biotechnol, 2018-02-15;0(0):1-11. 2018-02-15 [PMID: 29448837] (Bioassay, Rabbit)	Bioassay	Rabbit
M Desancé, R Contentin, L Bertoni, T Gomez-Ledu, T Branly, S Jacquet, JM Betsch, A Batho, F Legendre, F Audigié, P Galéra, M Demoor Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Int J Mol Sci, 2018-02-10;19(2):. 2018-02-10 [PMID: 29439436] (Bioassay, Equine)	Bioassay	Equine
J Nishida, K Miyazono, S Ehata Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-?-dependent and -independent mechanisms Oncogene, 2018-02-02;0(0):. 2018-02-02 [PMID: 29391598] (Bioassay, Human)	Bioassay	Human
T Branly, R Contentin, M Desancé, T Jacquel, L Bertoni, S Jacquet, F Mallein-Ge, JM Denoix, F Audigié, M Demoor, P Galéra Improvement of the Chondrocyte-Specific Phenotype upon Equine Bone Marrow Mesenchymal Stem Cell Differentiation: Influence of Culture Time, Transforming Growth Factors and Type I Collagen siRNAs on the Differentiation Index Int J Mol Sci, 2018-02-01;19(2):. 2018-02-01 [PMID: 29389887] (Bioassay, Equine)	Bioassay	Equine
DM Lord, JJ Bird, DM Honey, A Best, A Park, RR Wei, H Qiu Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF?1 antibody MAbs, 2018-02-01;0(0):0. 2018-02-01 [PMID: 29333938] (Human)		Human
U Mayer, A Benditz, S Grässel miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment Sci Rep, 2017-10-16;7(1):13297. 2017-10-16 [PMID: 29038440] (Bioassay, Human)	Bioassay	Human
D Parate, A Franco-Obr, J Fröhlich, C Beyer, AA Abbas, T Kamarul, JHP Hui, Z Yang Enhancement of mesenchymal stem cell chondrogenesis with short-term low intensity pulsed electromagnetic fields Sci Rep, 2017-08-25;7(1):9421. 2017-08-25 [PMID: 28842627] (Bioassay, Human)	Bioassay	Human
K Hino, K Horigome, M Nishio, S Komura, S Nagata, C Zhao, Y Jin, K Kawakami, Y Yamada, A Ohta, J Toguchida, M Ikeya Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva J. Clin. Invest., 2017-07-31;0(0):. 2017-07-31 [PMID: 28758906] (Bioassay, Human)	Bioassay	Human
S Stich, A Loch, SJ Park, T Häupl, J Ringe, M Sittinger Characterization of single cell derived cultures of periosteal progenitor cells to ensure the cell quality for clinical application PLoS ONE, 2017-05-31;12(5):e0178560. 2017-05-31 [PMID: 28562645] (Bioassay, Human)	Bioassay	Human
M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential PLoS ONE, 2017-05-18;12(5):e0177771. 2017-05-18 [PMID: 28542363] (Bioassay, Human)	Bioassay	Human
HH Wu, OK Lee Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells Stem Cell Res Ther, 2017-05-23;8(1):117. 2017-05-23 [PMID: 28535778] (Bioassay, Mouse)	Bioassay	Mouse
SI Pao, KH Chien, HT Lin, MC Tai, JT Chen, CM Liang Effect of microgravity on the mesenchymal stem cell characteristics of limbal fibroblasts J Chin Med Assoc, 2017-05-18;0(0):. 2017-05-18 [PMID: 28529022] (Bioassay, Mouse)	Bioassay	Mouse
JM Brunger, A Zutshi, VP Willard, CA Gersbach, F Guilak Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs Stem Cell Reports, 2017-04-27;0(0):. 2017-04-27 [PMID: 28457885] (Bioassay, Mouse)	Bioassay	Mouse
M Arase, Y Tamura, N Kawasaki, K Isogaya, R Nakaki, A Mizutani, S Tsutsumi, H Aburatani, K Miyazono, D Koinuma Dynamics of chromatin accessibility during TGF-?-induced EMT of Ras-transformed mammary gland epithelial cells Sci Rep, 2017-04-26;7(1):1166. 2017-04-26 [PMID: 28446749] (Bioassay, Mouse)	Bioassay	Mouse
L Mei, B Shen, P Ling, S Liu, J Xue, F Liu, H Shao, J Chen, A Ma, X Liu Culture-expanded allogenic adipose tissue-derived stem cells attenuate cartilage degeneration in an experimental rat osteoarthritis model PLoS ONE, 2017-04-18;12(4):e0176107. 2017-04-18 [PMID: 28419155] (Bioassay, Rat)	Bioassay	Rat
J Rodriguez, AS Pratta, N Abbassi, H Fabre, F Rodriguez, C Debard, J Adobati, F Boucher, F Mallein-Ge, C Auxenfans, O Damour, A Mojallal Evaluation of Three Devices for the Isolation of the Stromal Vascular Fraction from Adipose Tissue and for ASC Culture: A Comparative Study Stem Cells Int, 2017-02-22;2017(0):9289213. 2017-02-22 [PMID: 28321259] (Bioassay, Human)	Bioassay	Human
MD Truong, BH Choi, YJ Kim, MS Kim, BH Min Granulocyte macrophage-colony stimulating factor (GM-CSF) significantly enhances articular cartilage repair potential by microfracture Osteoarthr. Cartil, 2017-03-08;0(0):. 2017-03-08 [PMID: 28284999] (Bioassay, Rabbit)	Bioassay	Rabbit
SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE Mnch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres Neurotoxic reactive astrocytes are induced by activated microglia Nature, 2017-01-18;541(7638):481-487. 2017-01-18 [PMID: 28099414] (Bioassay, Human)	Bioassay	Human
Elias S, Schmidt A, Kannan V, Andersson J, Tegner J TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner. Front Immunol, 2016-12-23;7(0):603. 2016-12-23 [PMID: 28066414] (Bioassay, Human)	Bioassay	Human
Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation BMC Biotechnol, 2016-12-12;16(1):89. 2016-12-12 [PMID: 27955656] (Bioassay, Human)	Bioassay	Human
Mélanie Gadelorge Clinical-scale expansion of Adipose derived Stromal Cells starting from Stromal Vascular Fraction in a single-use bioreactor: Proof of concept for autologous applications J Tissue Eng Regen Med, 2017-05-12;0(0):. 2017-05-12 [PMID: 27943660] (Bioassay, Human)	Bioassay	Human
Sarah Hemming EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity, and accelerates remodeling FASEB J, 2016-12-01;0(0):. 2016-12-01 [PMID: 27934660] (Bioassay, Mouse)	Bioassay	Mouse
Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells PLoS ONE, 2016-12-01;11(12):e0167442. 2016-12-01 [PMID: 27907211] (Bioassay, Canine)	Bioassay	Canine
Weiguo Zou Bromodomain and Extra-terminal Proteins (BET) Inhibitors Suppress Chondrocyte Differentiation and Restrain Bone Growth J. Biol. Chem., 2016-11-07;0(0):. 2016-11-07 [PMID: 27821592] (Bioassay, Mouse)	Bioassay	Mouse
Aberrant Transforming Growth Factor-? Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia Stem Cells Transl Med, 2016-01-01;0(0):. 2016-01-01 [PMID: 27604218] (Bioassay, Mouse)	Bioassay	Mouse
Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow-derived counterparts J Tissue Eng, 2016-08-16;7(0):2041731416661. 2016-08-16 [PMID: 27579159] (Bioassay, Rat)	Bioassay	Rat
Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing Proc Natl Acad Sci USA, 2016-07-18;0(0):. 2016-07-18 [PMID: 27432980] (Bioassay, Human)	Bioassay	Human
IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice J Immunol, 2016-05-13;0(0):. 2016-05-13 [PMID: 27183574] (Bioassay, Human)	Bioassay	Human
Lepage S, Nagy K, Sung H, Kandel R, Nagy A, Koch T Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells. Stem Cells Dev, 2015-11-05;25(1):80-9. 2015-11-05 [PMID: 26414480] (Bioassay, Equine)	Bioassay	Equine
Russell K, Gibson T, Chong A, Co C, Koch T Canine Platelet Lysate Is Inferior to Fetal Bovine Serum for the Isolation and Propagation of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells. PLoS ONE, 2015-09-09;10(9):e0136621. 2015-09-09 [PMID: 26353112] (Bioassay, Canine)	Bioassay	Canine
Lee C, Rodeo S, Fortier L, Lu C, Erisken C, Mao J Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep. Sci Transl Med, 2014-12-10;6(266):266ra171. 2014-12-10 [PMID: 25504882] (Bioassay, Ovine)	Bioassay	Ovine
Liu G, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla R, Goebl A, Aizawa E, Kim N, Kim J, Dubova I, Li Y, Ren R, Benner C, del Sol A, Bueren J, Trujillo J, Surralles J, Cappelli E, Dufour C, Esteban C, Izpisua Belmonte J Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun, 2014-07-07;5(0):4330. 2014-07-07 [PMID: 24999918] (Bioassay, Human)	Bioassay	Human
Jakobsen R, Ostrup E, Zhang X, Mikkelsen T, Brinchmann J Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE, 2014-05-09;9(5):e96615. 2014-05-09 [PMID: 24816923] (Bioassay, Human)	Bioassay	Human
Chen P, Liu K, Hsu P, Wei C, Bai C, Ho L, Sytwu H, Yen B Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2. J Leukoc Biol, 2014-04-08;96(2):295-303. 2014-04-08 [PMID: 24714552] (Bioassay, Human)	Bioassay	Human
Karamichos D, Hutcheon A, Rich C, Trinkaus-Randall V, Asara J, Zieske J In vitro model suggests oxidative stress involved in keratoconus disease. Sci Rep, 2014-04-09;4(0):4608. 2014-04-09 [PMID: 24714342] (Bioassay, Human)	Bioassay	Human
Lee S, Yoon D, Paik S, Lee K, Jang Y, Lee J microRNA-495 inhibits chondrogenic differentiation in human mesenchymal stem cells by targeting Sox9. Stem Cells Dev, 2014-04-28;23(15):1798-808. 2014-04-28 [PMID: 24654627] (Bioassay, Human)	Bioassay	Human
Zhang H, Yin Y, Wang G, Liu Z, Liu L, Sun F Interleukin-6 disrupts blood-testis barrier through inhibiting protein degradation or activating phosphorylated ERK in Sertoli cells. Sci Rep, 2014-03-03;4(0):4260. 2014-03-03 [PMID: 24584780] (Bioassay, Rat)	Bioassay	Rat
Brunger J, Huynh N, Guenther C, Perez-Pinera P, Moutos F, Sanchez-Adams J, Gersbach C, Guilak F Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci U S A, 2014-02-18;111(9):E798-806. 2014-02-18 [PMID: 24550481] (Bioassay)	Bioassay
Karamichos D, Funderburgh M, Hutcheon A, Zieske J, Du Y, Wu J, Funderburgh J A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells. PLoS ONE, 2014-01-21;9(1):e86260. 2014-01-21 [PMID: 24465995] (Bioassay, Human)	Bioassay	Human
Belzile , Jean-Phi, Stark , Thomas J, Yeo , Gene W, Spector , Deborah Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. J Virol, 2014-01-22;88(8):4021-39. 2014-01-22 [PMID: 24453373] (Bioassay, Human)	Bioassay	Human
Boyette , Lisa B, Creasey , Olivia A, Guzik , Lynda, Lozito , Thomas, Tuan , Rocky S Human bone marrow-derived mesenchymal stem cells display enhanced clonogenicity but impaired differentiation with hypoxic preconditioning. Stem Cells Transl Med, 2014-01-16;3(2):241-54. 2014-01-16 [PMID: 24436440] (Bioassay, Human)	Bioassay	Human
Wada , Naohisa, Maeda , Hidefumi, Hasegawa , Daigaku, Gronthos , Stan, Bartold , Peter Ma, Menicanin , Danijela, Fujii , Shinsuke, Yoshida , Shinichi, Tomokiyo , Atsushi, Monnouchi , Satoshi, Akamine , Akifumi Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells. Stem Cells Dev, 2014-02-10;23(18):2225-36. 2014-02-10 [PMID: 24380401] (Bioassay, Human)	Bioassay	Human
Espagnolle N, Guilloton F, Deschaseaux F, Gadelorge M, Sensebe L, Bourin P CD146 expression on mesenchymal stem cells is associated with their vascular smooth muscle commitment. J Cell Mol Med, 2013-11-04;18(1):104-14. 2013-11-04 [PMID: 24188055] (Bioassay, Human)	Bioassay	Human
Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, Hollander A Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 2013-12-04;23(5):541-54. 2013-12-04 [PMID: 24172175] (Bioassay, Human)	Bioassay	Human
Guerit D, Philipot D, Chuchana P, Toupet K, Brondello J, Mathieu M, Jorgensen C, Noel D Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells. PLoS ONE, 2013-04-23;8(4):e62582. 2013-04-23 [PMID: 23626837] (Bioassay, Human)	Bioassay	Human
Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O MicroRNA-based promotion of human neuronal differentiation and subtype specification. PLoS ONE, 2013-03-18;8(3):e59011. 2013-03-18 [PMID: 23527072] (Bioassay, Human)	Bioassay	Human
Lund , Troy C, Kobs , Amanda J, Kramer , Ashley, Nyquist , Mick, Kuroki , Marcos T, Osborn , John, Lidke , Diane S, Low-Nam , Shalini, Blazar , Bruce R, Tolar , Jakub Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression. PLoS ONE, 2013-03-08;8(3):e58945. 2013-03-08 [PMID: 23520545] (Bioassay, Human)	Bioassay	Human
Li O, Tormin A, Sundberg B, Hyllner J, Le Blanc K, Scheding S Human embryonic stem cell-derived mesenchymal stroma cells (hES-MSCs) engraft in vivo and support hematopoiesis without suppressing immune function: implications for off-the shelf ES-MSC therapies. PLoS ONE, 2013-01-29;8(1):e55319. 2013-01-29 [PMID: 23383153] (Cell Culture, Human)	Cell Culture	Human
Qian H, Badaloni A, Chiara F, Stjernberg J, Polisetti N, Nihlberg K, Consalez G, Sigvardsson M Molecular characterization of prospectively isolated multipotent mesenchymal progenitors provides new insight into the cellular identity of mesenchymal stem cells in mouse bone marrow. Mol Cell Biol, 2012-11-26;33(4):661-77. 2012-11-26 [PMID: 23184664] (Bioassay, Mouse)	Bioassay	Mouse
Le M, Naridze R, Morrison J, Biggs L, Rhea L, Schutte B, Kaartinen V, Dunnwald M Transforming growth factor Beta 3 is required for excisional wound repair in vivo. PLoS ONE, 2012-10-26;7(10):e48040. 2012-10-26 [PMID: 23110169] (In Vivo, Mouse)	In Vivo	Mouse
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 2012-07-26;487(7408):505-9. 2012-07-26 [PMID: 22763448] (Bioassay, Human)	Bioassay	Human
Kawabata K, Ehata S, Komuro A, Takeuchi K, Miyazono K TGF-beta-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20. Oncogene, 2012-06-04;32(16):2096-106. 2012-06-04 [PMID: 22665052] (Bioassay, Human)	Bioassay	Human
Qian H, Le Blanc K, Sigvardsson M Primary Mesenchymal Stem and Progenitor Cells from Bone Marrow Lack Expression of CD44 Protein. J. Biol. Chem., 2012-05-31;287(31):25795-807. 2012-05-31 [PMID: 22654106] (Bioassay, Human)	Bioassay	Human
Asumda FZ, Chase PB Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol., 2011-10-12;12(0):44. 2011-10-12 [PMID: 21992089] (Bioassay, Rat)	Bioassay	Rat
Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 2011-07-07;286(34):30034-46. 2011-07-07 [PMID: 21737454] (Surface Plasmon Resonance, Human, Mouse)	Surface Plasmon Resonance	Human, Mouse
Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol. Biol. Cell, 2011-03-16;22(10):1686-98. 2011-03-16 [PMID: 21411626] (Bioassay, Canine)	Bioassay	Canine
Kawaguchi J, Nichols J, Gierl MS, Faial T, Smith A Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development, 2010-03-01;137(5):693-704. 2010-03-01 [PMID: 20147374] (Bioassay, Mouse)	Bioassay	Mouse
Moransard M, Sawitzky M, Fontana A, Suter T Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia, 2010-04-01;58(5):559-71. 2010-04-01 [PMID: 19941340] (Bioassay, Mouse)	Bioassay	Mouse
English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells. Clin. Exp. Immunol., 2009-02-03;156(1):149-60. 2009-02-03 [PMID: 19210524] (Differentiation, Differentiation, Human)	Differentiation, Differentiation	Human
Moioli EK, Clark PA, Sumner DR, Mao JJ Autologous stem cell regeneration in craniosynostosis. Bone, 2007-10-17;42(2):332-40. 2007-10-17 [PMID: 18023269] (In Vivo, Rat)	In Vivo	Rat
Fujikawa T, Matsumura S, Yamada H, Inoue K, Fushiki T Transforming growth factor-beta in the brain enhances fat oxidation via noradrenergic neurons in the ventromedial and paraventricular hypothalamic nucleus. Brain Res., 2007-08-09;1173(0):92-101. 2007-08-09 [PMID: 17765878] (In Vivo, Rat)	In Vivo	Rat
Neurohr C, Nishimura SL, Sheppard D Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am. J. Respir. Cell Mol. Biol., 2006-03-30;35(2):252-9. 2006-03-30 [PMID: 16574941] (Bioassay, Human)	Bioassay	Human
Nagineni CN, Kutty V, Detrick B, Hooks JJ Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol., 2005-04-01;203(1):35-43. 2005-04-01 [PMID: 15368539] (Bioassay, Human)	Bioassay	Human
Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A., 2004-08-13;101(34):12543-8. 2004-08-13 [PMID: 15310843] (Bioassay, Human, Primate - Macaca mulatta (Rhesus Macaque))	Bioassay	Human, Primate - Macaca mulatta (Rhesus Macaque)
Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22. 2004-01-12 [PMID: 14722222] (Bioassay, Human)	Bioassay	Human
Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. Int. J. Dev. Biol., 2003-02-01;47(1):15-29. 2003-02-01 [PMID: 12653248] (In Vivo, Xenopus)	In Vivo	Xenopus
Schmidt A, 2019, Gopfert C, Vlodavsky I, Volker W, Buddecke E Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta. 101211, 2002-03-01;81(3):138-44. 2002-03-01 [PMID: 11998865] (Bioassay, Bovine)	Bioassay	Bovine
Liu X, Kohyama T, Wang H, Zhu YK, Wen FQ, Kim HJ, Romberger DJ, Rennard SI Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am. J. Physiol. Lung Cell Mol. Physiol., 2002-05-01;282(5):L1049-56. 2002-05-01 [PMID: 11943670] (ELISA (Standard))	ELISA (Standard)
Simpson H, 2019, Robson SC, Bulmer JN, Barber A, Lyall F Transforming growth factor beta expression in human placenta and placental bed during early pregnancy. 6897, 2002-01-01;23(1):44-58. 2002-01-01 [PMID: 11869091] (ELISA (Standard))	ELISA (Standard)
Mozes MM, Hodics T, Kopp JB Isoform specificity of commercially-available anti-TGF-beta antibodies. J. Immunol. Methods, 1999-05-27;225(1):87-93. 1999-05-27 [PMID: 10365785] (Western Blot)	Western Blot
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Gene Symbol	TGFB3
Uniprot	P10600()

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Recombinant Human TGF-beta 3 Protein

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