Reactivity | Hu, MuSpecies Glossary |
Applications | WB, IHC |
Clone | 663921 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Concentration | LYOPH |
Immunogen | E. coli-derived recombinant human Tec Met1-Met187 Accession # P42680 |
Specificity | Detects human Tec in direct ELISAs and Western blots. |
Source | N/A |
Isotype | IgG2b |
Clonality | Monoclonal |
Host | Mouse |
Gene | TEC |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Concentration | LYOPH |
Reconstitution Instructions | Sterile PBS to a final concentration of 0.5 mg/mL. |
The tyrosine protein kinase Tec is an approximately 70 kDa member of the protein kinase superfamily, tyrosine protein family, and Tec subfamily. Human Tec is 631 amino acids (aa) in length. Amino acid residues 4-111 constitute a Tec pleckstrin homology (PH) domain, and aa 113-149 make up a Btk-type zinc finger. Residues 179-239 form a Src homology 3 (SH3) domain, and aa 247-345 make up a Src homology 2 (SH2) domain. The region involving positions 365-620 constitutes the catalytic domain of the protein tyrosine kinases. Human Tec shares 94% aa sequence identity with mouse Tec. Human Tec is expressed in hematopoietic cell lines including B-cell, T-cell, and myeloid lineages.
Secondary Antibodies |
Isotype Controls |
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