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SLX4 Antibody

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Independent Antibodies: Immunoprecipitation: BTBD12 Antibody [NBP1-28679] - Detection of human BTBD12 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
Validated by:
 

Independent Antibodies

       

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SLX4 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1650 and 1700 of human SLX4 using the numbering given in entry NP_115820.2 (GeneID 84464).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLX4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry Reported in (PMID: 21655083)
  • Immunoprecipitation 2 - 10 ug/mg lysate
Publications
Read Publications using NBP1-28679.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SLX4 Antibody

  • BTB (POZ) domain containing 12
  • BTB/POZ domain-containing protein 12
  • BTBD12
  • BTBD12structure-specific endonuclease subunit SLX4
  • FANCP
  • KIAA1784
  • KIAA1784MUS312
  • KIAA1987
  • KIAA1987FANCP
  • SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • SLX4

Background

BTBD12 (BTBD12 domain-containing protein 12) has been identified as the human ortholog of the yeast Slx4p and drosophila MUS312 DNA repair factors. BTBD12 is an ATM/ATR checkpoint substrate that functions as part of a Holliday junction resolvase and is important for DNA interstrand crosslink repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP1-28679
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Applications: IHC, IP, WB (-)

Publications for SLX4 Antibody (NBP1-28679)(3)

Reviews for SLX4 Antibody (NBP1-28679) (0)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for SLX4 Antibody (NBP1-28679). (Showing 1 - 1 of 1 FAQs).

  1. What concentration do you recommend using this antibody at for probing Westerns?
    • Please note that our product BTBD12 Antibody (NBP1-28679) is recommended for immunoprecipitation (IP), but not for Western blot - the minus sign next to 'WB' on the datasheet denotes 'Western blot - negative' and means that testing has indicated that this product is not suitable for western blot.

Secondary Antibodies

 

Isotype Controls

Additional SLX4 Products

Array NBP1-28679

Blogs on SLX4.

FANCD2 (Fanconi anemia subunit D2 protein)
Fanconi anemia (FANC) is a rare, autosomal-recessive genetic disorder that is a heterogeneous cancer susceptibility condition that manifests with a wide range of symptoms such as congenital malformations, deteriorating bone marrow failure, DNA-dama...  Read full blog post.

FANCD2: A big component of the DNA repair crew
The genetic disorder known as Fanconi anemia (FANC) is a heterogeneous, autosomal-recessive cancer susceptibility condition characterized by a wide array of symptoms. These include congenital malformations, progressive bone marrow failure, DNA-damage ...  Read full blog post.

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Bioinformatics

Gene Symbol SLX4
Entrez
Uniprot