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SLX4 Antibody [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

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SLX4 Antibody [DyLight 755] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1650 and 1700 of human SLX4 using the numbering given in entry NP_115820.2 (GeneID 84464).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLX4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SLX4 Antibody [DyLight 755]

  • BTB (POZ) domain containing 12
  • BTB/POZ domain-containing protein 12
  • BTBD12
  • BTBD12structure-specific endonuclease subunit SLX4
  • FANCP
  • KIAA1784
  • KIAA1784MUS312
  • KIAA1987
  • KIAA1987FANCP
  • SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • SLX4

Background

BTBD12 (BTBD12 domain-containing protein 12) has been identified as the human ortholog of the yeast Slx4p and drosophila MUS312 DNA repair factors. BTBD12 is an ATM/ATR checkpoint substrate that functions as part of a Holliday junction resolvase and is important for DNA interstrand crosslink repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional SLX4 Products

Array NBP1-28679IR

Blogs on SLX4.

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Fanconi anemia (FANC) is a rare, autosomal-recessive genetic disorder that is a heterogeneous cancer susceptibility condition that manifests with a wide range of symptoms such as congenital malformations, deteriorating bone marrow failure, DNA-dama...  Read full blog post.

FANCD2: A big component of the DNA repair crew
The genetic disorder known as Fanconi anemia (FANC) is a heterogeneous, autosomal-recessive cancer susceptibility condition characterized by a wide array of symptoms. These include congenital malformations, progressive bone marrow failure, DNA-damage ...  Read full blog post.

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Bioinformatics

Gene Symbol SLX4