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RUNX3/CBFA3 Antibody (527327) [DyLight 488]

 
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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, CyTOF-ready, Flow, ICC/IF
Clone
527327
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC3765U-100UG
Alexa Fluor 405
IC3765V-100UG
Alexa Fluor 488
IC3765G-100UG
Alexa Fluor 532
FAB3765X
Alexa Fluor 594
IC3765T-100UG
Alexa Fluor 647
IC3765R-100UG
Alexa Fluor 700
IC3765N-100UG
Alexa Fluor 750
IC3765S-100UG
Allophycocyanin
IC3765A
Biotin
FAB3765B
CoraFluor 1
FAB3765CL1
DyLight 350
FAB3765D
DyLight 405
FAB3765E
DyLight 550
FAB3765L
DyLight 594
FAB3765M
DyLight 650
FAB3765W
DyLight 680
FAB3765Y
DyLight 755
FAB3765Z
FITC
FAB3765F
HRP
FAB3765H
Janelia Fluor 525
FAB3765JF525
Janelia Fluor 549
FAB3765I
Janelia Fluor 585
FAB3765JF585
Janelia Fluor 635
FAB3765JF635
Janelia Fluor 646
FAB3765J
Janelia Fluor 669
FAB3765JF669
PE
FAB3765P
PerCP
FAB3765C
Unconjugated
MAB3765
mFluor Violet 450 SE
FAB3765MFV450
mFluor Violet 500 SE
FAB3765MFV500
mFluor Violet 610 SE
FAB3765MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3765
Carrier Free
MAB3765
Carrier Free
IC3765A
Carrier Free
MAB3765-SP
Carrier Free
IC3765S-100UG
Carrier Free
IC3765R-100UG
Carrier Free
IC3765N-100UG
Carrier Free
IC3765G-100UG
Carrier Free
IC3765V-100UG
Carrier Free
IC3765U-100UG
Carrier Free
IC3765T-100UG
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RUNX3/CBFA3 Antibody (527327) [DyLight 488] Summary

Immunogen
E. coli-derived recombinant human RUNX3/CBFA3
Lys186-Tyr415
Accession # Q13761
Specificity
Detects human and mouse RUNX3/CBFA3 in Western blots.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
RUNX3
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry
  • Intracellular Staining by Flow Cytometry
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for RUNX3/CBFA3 Antibody (527327) [DyLight 488]

  • Acute myeloid leukemia 2 protein
  • AML2
  • AML2SL3/AKV core-binding factor alpha C subunit
  • CBFA3
  • CBFA3MGC16070
  • CBF-alpha-3
  • PEA2 alpha C
  • PEA2-alpha C
  • PEBP2 alpha C
  • PEBP2A3
  • PEBP2A3FLJ34510
  • PEBP2AC
  • PEBP2-alpha C
  • runt domain, alpha subunit 3
  • runt-related transcription factor 3
  • RUNX3
  • SL3-3 enhancer factor 1 alpha C subunit
  • transcription factor AML2

Background

RUNX3 binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. RUNX3 consists of a heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer through the Runt domain. DNA-binding is increased by heterodimerization.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RUNX3