Species: Hu, Mu
Applications: WB, Simple Western, CyTOF-ready, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
RUNX3 binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. RUNX3 consists of a heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer through the Runt domain. DNA-binding is increased by heterodimerization.
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human Rat |
Product By Gene ID |
864 |
Alternate Names |
- Acute myeloid leukemia 2 protein
- AML2SL3/AKV core-binding factor alpha C subunit
- CBFA3MGC16070
- CBF-alpha-3
- PEA2 alpha C
- PEA2-alpha C
- PEBP2 alpha C
- PEBP2A3FLJ34510
- PEBP2-alpha C
- runt domain, alpha subunit 3
- runt-related transcription factor 3
- SL3-3 enhancer factor 1 alpha C subunit
- transcription factor AML2
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