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RUNX3/CBFA3 Antibody (527327) [Biotin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, CyTOF-ready, Flow, ICC/IF
Clone
527327
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

RUNX3/CBFA3 Antibody (527327) [Biotin] Summary

Immunogen
E. coli-derived recombinant human RUNX3/CBFA3
Lys186-Tyr415
Accession # Q13761
Specificity
Detects human and mouse RUNX3/CBFA3 in Western blots.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
RUNX3
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry
  • Intracellular Staining by Flow Cytometry
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for RUNX3/CBFA3 Antibody (527327) [Biotin]

  • Acute myeloid leukemia 2 protein
  • AML2
  • AML2SL3/AKV core-binding factor alpha C subunit
  • CBFA3
  • CBFA3MGC16070
  • CBF-alpha-3
  • PEA2 alpha C
  • PEA2-alpha C
  • PEBP2 alpha C
  • PEBP2A3
  • PEBP2A3FLJ34510
  • PEBP2AC
  • PEBP2-alpha C
  • runt domain, alpha subunit 3
  • runt-related transcription factor 3
  • RUNX3
  • SL3-3 enhancer factor 1 alpha C subunit
  • transcription factor AML2

Background

RUNX3 binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. RUNX3 consists of a heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer through the Runt domain. DNA-binding is increased by heterodimerization.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for RUNX3/CBFA3 Antibody (FAB3765B) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for RUNX3/CBFA3 Antibody (FAB3765B)

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Bioinformatics

Gene Symbol RUNX3