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Coagulation Factor XIV/Protein C Antibody

Images

 
Immunohistochemistry-Paraffin: Coagulation Factor XIV/Protein C Antibody [NBP1-86509] - Staining of human small intestine shows moderate positivity in plasma in blood vessels.
Immunohistochemistry: Coagulation Factor XIV/Protein C Antibody [NBP1-86509] - Staining of human liver shows extracellular immunoreactivity in blood vessel.
Immunohistochemistry-Paraffin: Coagulation Factor XIV/Protein C Antibody [NBP1-86509] - Staining of human fallopian tube shows positivity in plasma.
Immunohistochemistry-Paraffin: Coagulation Factor XIV/Protein C Antibody [NBP1-86509] - Staining of human liver shows weak cytoplasmic positivity in hepatocytes and strong positivity in plasma.
Immunohistochemistry-Paraffin: Coagulation Factor XIV/Protein C Antibody [NBP1-86509] - Staining of human skin shows no positivity in squamous epithelial cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Coagulation Factor XIV/Protein C Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: AHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PROC
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Coagulation Factor XIV/Protein C Protein (NBP1-86509PEP)
Publications
Read Publication using NBP1-86509.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Coagulation Factor XIV/Protein C Antibody

  • Anticoagulant protein C
  • APC
  • Autoprothrombin IIA
  • Blood coagulation factor XIV
  • Coagulation Factor XIV
  • EC 3.4.21
  • EC 3.4.21.69
  • PC
  • PROC
  • PROC1
  • protein C (inactivator of coagulation factors Va and VIIIa)
  • Protein C
  • vitamin K-dependent protein C

Background

Protein C is a vitamin K-dependent serine protease that is produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa inhibiting blood coagulation. The molecular weight of the active enzyme is 55 kDa and the normal concentration in human plasma is approximately 1-3 ng/ml while the concentration of the proenzyme is approximately 3 ug/mL due to the very fast turnover.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Coagulation Factor XIV/Protein C Antibody (NBP1-86509)(1)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PROC