Systemic and local HBP and resistin responses in septic patients.HBP and resistin levels in plasma collected from patients on the day of inclusion were measured with ELISA, for details see Experimental procedures. (A,B) ...read more
Subcellular localization of HBP and resistin in neutrophils.Neutrophils from healthy donors were isolated and stimulated with LPS (50 ng/ml), fMLP (5 μg/ml) or streptococcal M1-protein (1 μg/ml) for 2 h. The ...read more
E. coli-derived recombinant human Resistin Ser17-Pro108 Accession # Q9HD89
Specificity
Detects human Resistin in direct ELISAs and Western blots. In these formats, this antibody shows less than 2% cross-reactivity with rmResistin, rmRELM alpha and rmRELM beta .
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
RETN
Purity Statement
Antigen Affinity-purified
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Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein
Cysteine-rich secreted protein A12-alpha-like 2
Cysteine-rich secreted protein FIZZ3
FIZZ3
FIZZ3MGC126603
found in inflammatory zone 3
HXCP1
Resistin
RETN
RETN1
RSTNXCP1
Background
Human Resistin is an 11-12 kDa member of a small family of inflammation-related cysteine-rich polypeptides. It is named for its antagonistic activity towards insulin (resistance to insulin) and contains five intrachain disulfide bonds that generate a mixture of alpha -helices and beta -sheets. Secreted resistin forms disulfide-linked homodimers that likely oligomerize. Resistin may also form nondisulfide-linked heterodimers with RELM beta . One alternate splice form exists that shows an in-frame 26 amino acid (aa) deletion between amino acids 40 - 65. The significance is unclear. Mature human Resistin is 50% aa identical to human RELM beta and 56% aa identical to mouse Resistin.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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