Plasminogen Antibody

Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200mg/L. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 2 applications: ELISA, WB.

Showing Publications 1 - 6 of 6.

Publications using NB600-930	Applications	Species
Floden AM, Watt JA, Brissette CA. Borrelia burgdorferi Enolase Is a Surface-Exposed Plasminogen Binding Protein. PLoS ONE 20116(11). [PMID: 22087329]
Verma A, Brissette CA, Bowman AA et al. Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. Infect Immun;78(5):2053-9. 2010-05-01 [PMID: 20160016] (ELISA, Human)	ELISA	Human
Seling A, Siegel C, Fingerle V et al. Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen. Infect Immun;78(1):39-48. 2010-01-01 [PMID: 19858303] (ELISA, Human)	ELISA	Human
Woodman ME, Cooley AE, Avdiushko R et al. Roles for phagocytic cells complement in controlling relapsing fever infection. J Leukoc Biol;86(3):727-736. 2009-01-01 [PMID: 19458267]
Brissette CA, Haupt K, Barthel D et al. Borrelia burgdorferi Infection-Associated Surface Proteins ErpP, ErpA, ErpC Bind Human Plasminogen. Infect Immun;77(1):300-306. 2009-01-01 [PMID: 19001079]
Basile DP, Fredrich K, Weihrauch D, Hattan N, Chilian WM Angiostatin and matrix metalloprotease expression following ischemic acute renal failure. Am J Physiol Renal Physiol. 2004-01-01 [PMID: 15075185] (WB, Rat)	WB	Rat

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Catherine Brissette	ELISA	Other	03/03/2011	View Summary Application ELISA Sample Tested Recombinant protein Species Other Lot 6571
	5 reviewed by: Ashutosh Verma	ELISA	Other	07/02/2010	View Summary Application ELISA Sample Tested Recombinant protein Species Other

Array NB600-930

• Plasminogen Antibodies
• Plasminogen ELISA Kits
• Plasminogen Lysate
• Plasminogen Protein
• Plasminogen Proteins and Enzyme
• Plasminogen ELISA