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N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [NBP2-62607] - Immunohistochemistry analysis in human testis and skeletal muscle tissues using Anti-GALNS ...read more
Immunohistochemistry-Paraffin: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [NBP2-62607] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [NBP2-62607] - Staining of human skeletal muscle shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: TTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GALNS
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
N-Acetylgalactosamine-6-Sulfatase/GALNS Recombinant Protein Antigen (NBP2-62607PEP)

Reactivity Notes

Mouse (82%), Rat (81%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody

  • Chondroitinase
  • Chondroitinsulfatase
  • EC 3.1.6
  • EC 3.1.6.4
  • FLJ17434
  • FLJ42844
  • FLJ98217
  • GA6S
  • galactosamine (N-acetyl)-6-sulfate sulfatase
  • Galactose-6-Sulfate Sulfatase
  • GalNAc6S Sulfatase
  • GALNAC6S
  • GALNS
  • GAS
  • MPS4A
  • NAcetylgalactosamine6Sulfatase
  • N-Acetylgalactosamine-6-Sulfatase
  • N-acetylgalactosamine-6-sulfate sulfatase

Background

GALNS encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GALNS