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MAT2A Antibody (3A2) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clone
3A2
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-28605AF350
Alexa Fluor 405
NBP1-28605AF405
Alexa Fluor 488
NBP1-28605AF488
Alexa Fluor 532
NBP1-28605AF532
Alexa Fluor 594
NBP1-28605AF594
Alexa Fluor 647
NBP1-28605AF647
Alexa Fluor 700
NBP1-28605AF700
Alexa Fluor 750
NBP1-28605AF750
Biotin
NBP1-28605B
CoraFluor 1
NBP1-28605CL1
DyLight 350
NBP1-28605UV
DyLight 405
NBP1-28605V
DyLight 488
NBP1-28605G
DyLight 550
NBP1-28605R
DyLight 594
NBP1-28605DL594
DyLight 650
NBP1-28605C
DyLight 680
NBP1-28605FR
DyLight 755
NBP1-28605IR
FITC
NBP1-28605F
HRP
NBP1-28605H
Janelia Fluor 549
NBP1-28605JF549
Janelia Fluor 585
NBP1-28605JF585
Janelia Fluor 635
NBP1-28605JF635
Janelia Fluor 646
NBP1-28605JF646
Janelia Fluor 669
NBP1-28605JF669
Unconjugated
NBP1-28605
mFluor Violet 450 SE
NBP1-28605MFV450
mFluor Violet 500 SE
NBP1-28605MFV500
mFluor Violet 610 SE
NBP1-28605MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-28605
BSA Free
NBP1-28605
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MAT2A Antibody (3A2) [Janelia Fluor® 525] Summary

Immunogen
Recombinant human MAT2A (1-395aa) purified from E. coli (NP_005902).
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MAT2A
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MAT2A Antibody (3A2) [Janelia Fluor® 525]

  • AdoMet synthase 2
  • AMS2
  • EC 2.5.1.6
  • MAT 2
  • MAT2A
  • MATA2
  • MATA2SAMS2adoMet synthetase 2
  • MATII
  • MAT-II
  • Methionine adenosyltransferase 2
  • Methionine adenosyltransferase II
  • methionine adenosyltransferase II, alpha
  • S-adenosylmethionine synthase isoform type-2
  • S-adenosylmethionine synthetase isoform type-2
  • SAMS2

Background

MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on MAT2A.

Check out the latest blog posts on MAT2A.
MAT2A - A Protien Coding Gene
The enzyme S-adenosylmethionine synthetase, or MAT, catalyzes the formation of S- adenosylmethionine (AdoMet or SAMe) from methionine and ATP. AdoMet is the principal biological source of synthesized methyl, and is found in all cells but most prominen...  Read full blog post.
MAT2a, MAT2b, HIF-1 alpha: Roles in Liver Cancer and DNA methylation
Methionine Adenosyltransferase II alpha, also known as MAT2a, is a catalytic subunit of methionine adenosyltransferase (MAT) and essential enzyme for the catalysis of the principle biological methyl donor, S-adenosylmethionine (SAM) from methionine an...  Read full blog post.
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Bioinformatics

Gene Symbol MAT2A