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IRF7 Antibody [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, KO
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-06987AF350
Alexa Fluor 405
NBP3-06987AF405
Alexa Fluor 488
NBP3-06987AF488
Alexa Fluor 532
NBP3-06987AF532
Alexa Fluor 594
NBP3-06987AF594
Alexa Fluor 647
NBP3-06987AF647
Alexa Fluor 700
NBP3-06987AF700
Alexa Fluor 750
NBP3-06987AF750
Biotin
NBP3-06987B
CoraFluor 1
NBP3-06987CL1
DyLight 350
NBP3-06987UV
DyLight 405
NBP3-06987V
DyLight 488
NBP3-06987G
DyLight 550
NBP3-06987R
DyLight 594
NBP3-06987DL594
DyLight 650
NBP3-06987C
DyLight 680
NBP3-06987FR
DyLight 755
NBP3-06987IR
FITC
NBP3-06987F
HRP
NBP3-06987H
Janelia Fluor 525
NBP3-06987JF525
Janelia Fluor 549
NBP3-06987JF549
Janelia Fluor 585
NBP3-06987JF585
Janelia Fluor 646
NBP3-06987JF646
Janelia Fluor 669
NBP3-06987JF669
PerCP
NBP3-06987PCP
Unconjugated
NBP3-06987
mFluor Violet 450 SE
NBP3-06987MFV450
mFluor Violet 500 SE
NBP3-06987MFV500
mFluor Violet 610 SE
NBP3-06987MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-06987
BSA Free
NBP3-06987
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IRF7 Antibody [Janelia Fluor® 635] Summary

Immunogen
Antibody was raised against a peptide corresponding to 17 amino acids near the center of human IRF7. The immunogen is located within amino acids 200-230 of IRF7.
Specificity
Several isoforms of IRF7 are known to exist. Human IRF7 has 4 isoforms, including isoform A (503aa, 54kD), isoform B (474aa, 52kD), isoform C (164aa, 18kD) and isoform D (516aa, 56kD). Mouse IRF7 has one isoform (457aa, 51kD) and Rat IRF7 also has one isoform (456aa, 51kD). NBP3-06987 can detect human isoforms and mouse, and possibly can detect rat.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IRF7
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IRF7 Antibody [Janelia Fluor® 635]

  • interferon regulatory factor 7
  • interferon regulatory factor-7H
  • IRF-7
  • IRF7A
  • IRF-7H

Background

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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[Janelia Fluor®
NBP3-06987JF635
IRF7 Antibody [Janelia Fluor® 635]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, KO

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on IRF7.

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TLR7 and Immune Response Regulation
Toll-like receptor 7 (TLR7) is a protein encoded by the TLR7 gene in humans and is a member of TLR family. TLRs controls host immune response against pathogens (e.g. viruses, bacteria and fungi) through recognition of pathogen-associated molecular pat...  Read full blog post.
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Bioinformatics

Gene Symbol IRF7