IKK beta Antibody (725818)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

I kappa B kinase beta (IKK beta ) is also known as IKBKB and IKK2. The classical active IKK complex, composed of IKK alpha , IKK beta , and two forms of processed IKK gamma , phosphorylates and inactivates I kappa B, resulting in the release and nuclear translocation of active NF kappa B. Like IKK alpha , IKK beta contains kinase (aa 15-300), leucine zipper (aa 458‑479), and helix-loop-helix (aa 605-644) domains. NF kappa B-inducing kinase (NIK) phosphorylates and activates IKK alpha /IKK beta heterodimers. Within amino acids 530‑757, mouse IKKb shares 89% and 96% aa sequence identity with human and rat IKKb, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 6 of 6.

Publications using MAB7155	Applications	Species
H Fujita, T Fujita, H Fujii IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis Cells, 2022-04-25;11(9):. 2022-04-25 [PMID: 35563758] (Western Blot, Mouse)	Western Blot	Mouse
LCC Araujo, KB Feitosa, GM Murata, IC Furigo, SA Teixeira, CF Lucena, LM Ribeiro, MN Muscará, SKP Costa, J Donato, S Bordin, R Curi, CRO Carvalho Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD Sci Rep, 2018-07-20;8(1):11013. 2018-07-20 [PMID: 30030460] (Western Blot, Mouse)	Western Blot	Mouse
Evangelos Giampazolias, Barbara Zunino, Sandeep Dhayade, Florian Bock, Catherine Cloix, Kai Cao et al. Mitochondrial permeabilization engages NF-kappa B-dependent anti-tumour activity under caspase deficiency Nature Cell Biology 9/1/2017 [PMID: 28846096]
Abhisek Mitra IL6 mediated inflammatory loop reprograms normal to EMT(+) metastatic CSCs in pre-neoplastic liver of TGF? deficient ?2SP(+/-) mice Hepatology, 2017-01-20;0(0):. 2017-01-20 [PMID: 27863449] (Western Blot, Mouse)	Western Blot	Mouse
Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, Popovych N, Helgason E, Schoeffler A, Jeet S, Ramamoorthi N, Kategaya L, Newman R, Horikawa K, Dugger D, Sandoval W, Mukund S, Zindal A, Martin F, Quan C, Tom J, Fairbrother W, Townsend M, Warming S, DeVoss J, Liu J, Dueber E, Caplazi P, Lee W, Goodnow C, Balazs M, Yu K, Kolumam G, Dixit V Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Nature, 2015-12-09;528(7582):370-5. 2015-12-09 [PMID: 26649818] (Western Blot, Mouse)	Western Blot	Mouse
Hsu-Ping Kuo, Zhong Wang, Dung-Fang Lee, Masayuki Iwasaki, Jesus Duque-Afonso, Stephen H.K. Wong et al. Epigenetic Roles of MLL Oncoproteins Are Dependent on NF-kappa B Cancer Cell 10/14/2013 [PMID: 24054986]

Array MAB7155

• IKK beta Antibodies
• IKK beta ELISA Kits
• IKK beta Lysate
• IKK beta Proteins