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Glut2 Antibody (205115) [Phycoerythrin]

Images

 
beta TC-6 mouse beta cell insulinoma cell line was stained with Rat Anti-Mouse Glut2 PE-conjugated Monoclonal Antibody (Catalog # FAB1440P, filled histogram) or isotype control antibody (Catalog # IC013P, open ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
205115
Clonality
Monoclonal
Host
Rat
Conjugate
Phycoerythrin

Order Details

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Glut2 Antibody (205115) [Phycoerythrin] Summary

Immunogen
CHO Chinese hamster ovary cell line transfected with mouse Glut2
Met1-Val523
Accession # P14246
Specificity
Detects mouse Glut2. Recognizes mouse Glut2-transfected NS0 cells but not NS0 control transfectants. It also detects Glut2 on mouse insulinoma beta TC-6 cells (1).
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
SLC2A2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Glut2 Antibody (205115) [Phycoerythrin]

  • GLUT2 Glucose transporter type 2, liver
  • Glut2
  • GLUT-2
  • SLC2A2
  • solute carrier family 2 (facilitated glucose transporter), member 2
  • solute carrier family 2, facilitated glucose transporter member 2

Background

Glut2, also known as SLC2A2, belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane glycoprotein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells, and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1, 2).

  1. Poitout, V. et al. (1995) Diabetes 44:306.
  2. Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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By Jamshed Arslan, Pharm. D., PhD. What Are GluTs?Mammalian cell metabolism is incomplete without glucose   . Glucose is a monosaccharide that is transported to the cells through facilitative diffusion, a ...  Read full blog post.

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Bioinformatics

Gene Symbol SLC2A2
Uniprot