beta TC-6 mouse beta cell insulinoma cell line was stained with Rat Anti-Mouse Glut2 APC-conjugated Monoclonal Antibody (Catalog # FAB1440A, filled histogram) or isotype control antibody (Catalog # IC013A, open ...read more
CHO Chinese hamster ovary cell line transfected with mouse Glut2 Met1-Val523 Accession # P14246
Specificity
Detects mouse Glut2. Recognizes mouse Glut2-transfected NS0 cells but not NS0 control transfectants. It also detects Glut2 on mouse insulinoma beta TC-6 cells (1).
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
SLC2A2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Glut2 Antibody (205115) [Allophycocyanin]
GLUT2 Glucose transporter type 2, liver
Glut2
GLUT-2
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
solute carrier family 2, facilitated glucose transporter member 2
Background
Glut2, also known as SLC2A2, belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane glycoprotein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells, and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1, 2).
Poitout, V. et al. (1995) Diabetes 44:306.
Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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