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gamma C Crystallin Antibody

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Western Blot: gamma C Crystallin Antibody [NBP1-32557] - Various tissue extracts (50 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with gamma C Crystallin antibody diluted at 1:20000. The ...read more

Product Details

Summary
Reactivity Hu, Mu, Pm, RMSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

  • Size / Catalog#QtyPrice
    NBP1-32557
    100 ul
    $449.00
    2-4 Business Days
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gamma C Crystallin Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human gamma C Crystallin. The exact sequence is proprietary.
Predicted Species
Rhesus Macaque (96%), Chimpanzee (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRYGC
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:20000
Theoretical MW
21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Bovine (85%), Guinea pig (86%), Mouse (84%), Rat (85%), Dog (87%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for gamma C Crystallin Antibody

  • CCL
  • CRYG3gamma-C-crystallin
  • crystallin, gamma C
  • crystallin, gamma-3
  • Gamma-C-crystallin
  • Gamma-crystallin 2-1
  • Gamma-crystallin 3
  • gamma-crystallin C

Background

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRYGC