Human CCL22/MDC Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Macrophage-derived chemokine (MDC), also named stimulated T cell chemotactic protein (STCP-1) and ABCD-1, and now designated as CCL22, is a CC chemokine initially isolated from clones of monocyte-derived macrophages. At the amino acid sequence level, MDC shows less than 35% identity to other CC chemokine family members. Human MDC is expressed in dendritic cells, macrophages and activated monocytes. In addition, MDC expression is detected in thymus, lymph node and appendix tissues. At the amino acid sequence level, mouse and human MDC share 64% identity and 83% similarity.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 31. Show All 31 Publications. Collapse Publications.

Publications using DMD00	Applications	Species
Song, HK;Park, SH;Kim, HJ;Jang, S;Choo, BK;Kim, HK;Kim, T; Inhibitory effect of Sanguisorba hakusanensis Makino ethanol extract on atopic dermatitis-like responses in NC/Nga mice and human keratinocytes Scientific reports 2023-09-05 [PMID: 37670127] (Human)		Human
Nelke, C;Schroeter, CB;Stascheit, F;Huntemann, N;Pawlitzki, M;Willison, AG;R�uber, S;Melzer, N;Distler, U;Tenzer, S;St�hler, K;Roos, A;Meisel, A;Meuth, SG;Ruck, T; Eculizumab treatment alters the proteometabolome beyond the inhibiton of complement JCI insight 2023-05-25 [PMID: 37227781] (Human)		Human
A Jorapur, LA Marshall, S Jacobson, M Xu, S Marubayash, M Zibinsky, DX Hu, O Robles, JJ Jackson, V Baloche, P Busson, D Wustrow, DG Brockstedt, O Talay, PD Kassner, G Cutler EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22 PloS Pathogens, 2022-01-13;18(1):e1010200. 2022-01-13 [PMID: 35025968] (Human)		Human
OM Ibrahim, PH Basse, W Jiang, K Guru, G Chatta, P Kalinski NF&kapppaB-Activated COX2/PGE2/EP4 Axis Controls the Magnitude and Selectivity of BCG-Induced Inflammation in Human Bladder Cancer Tissues Cancers, 2021-03-16;13(6):. 2021-03-16 [PMID: 33809455] (Human)		Human
Q Wang, E Schmoeckel, BP Kost, C Kuhn, A Vattai, T Vilsmaier, S Mahner, D Mayr, U Jeschke, HH Heidegger Higher CCL22+ Cell Infiltration is Associated with Poor Prognosis in Cervical Cancer Patients Cancers (Basel), 2019-12-12;11(12):. 2019-12-12 [PMID: 31842422] (Human)		Human
S Pekkala, A Keskitalo, E Kettunen, S Lensu, N Nykänen, T Kuopio, O Ritvos, J Hentilä, TA Nissinen, JJ Hulmi Blocking Activin Receptor Ligands Is Not Sufficient to Rescue Cancer-Associated Gut Microbiota-A Role for Gut Microbial Flagellin in Colorectal Cancer and Cachexia? Cancers (Basel), 2019-11-15;11(11):. 2019-11-15 [PMID: 31731747] (Human)		Human
D Bao, J Zhao, X Zhou, Q Yang, Y Chen, J Zhu, P Yuan, J Yang, T Qin, S Wan, J Xing Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression Oncogene, 2019-03-20;0(0):. 2019-03-20 [PMID: 30894684] (Human)		Human
TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee Changes in the Anti-Allergic Activities of Sesame by Bioconversion Nutrients, 2018-02-14;10(2):. 2018-02-14 [PMID: 29443928] (Human)		Human
MR Pranzatell, ED Tate, TJ Allison Case-control, exploratory study of cerebrospinal fluid chemokines/cytokines and lymphocyte subsets in childhood Tourette syndrome with positive streptococcal markers Cytokine, 2017-03-10;96(0):49-53. 2017-03-10 [PMID: 28288328] (Human)		Human
Zhang W, Zheng X, DU L, Sun J, Shen Z, Shi C, Sun S, Zhang Z, Chen X, Qin M, Liu X, Tao J, Jia L, Fan H, Zhou B, Yu Y, Ying H, Hui L, Liu X, Yi X, Liu X, Zhang L, Duan S High salt primes a specific activation state of macrophages, M(Na). Cell Res, 2015-07-24;25(8):893-910. 2015-07-24 [PMID: 26206316] (Human)		Human
Shi G, Han J, Liu G, Hao Y, Ma Y, Li T, Wu X, Zhang H, Liu Y, Wang B, Kong Y, Zhou J, Zeng H Expansion of activated regulatory T cells by myeloid-specific chemokines via an alternative pathway in CSF of bacterial meningitis patients. Eur J Immunol, 2013-12-02;44(2):420-30. 2013-12-02 [PMID: 24155161] (Human)		Human
Pranzatelli , Michael, Tate , Elizabet, McGee , Nathan R, Travelstead , Anna L, Colliver , Jerry A, Ness , Jayne M, Ransohoff , Richard BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy. J Neuroinflammation, 2013-01-16;10(0):10. 2013-01-16 [PMID: 23324534] (Human)		Human
Rai AK, Thakur CP, Singh A Regulatory T cells suppress T cell activation at the pathologic site of human visceral leishmaniasis. PLoS ONE, 2012-02-08;7(2):e31551. 2012-02-08 [PMID: 22347492] (Human)		Human
Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J. Clin. Invest., 2010-04-12;120(5):1645-62. 2010-04-12 [PMID: 20389019] (Human)		Human
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J. Immunol., 2010-02-17;184(6):2886-98. 2010-02-17 [PMID: 20164417] (Human)		Human
Narbutt J, Lesiak A, Sysa-Jedrzeiowska A, Zakrzewski M, Bogaczewicz J, Stelmach I, Kuna P The imbalance in serum concentration of Th-1- and Th-2-derived chemokines as one of the factors involved in pathogenesis of atopic dermatitis. Mediators Inflamm., 2009-07-22;2009(0):269541. 2009-07-22 [PMID: 19639049] (Human)		Human
Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, Stingl G, Eppel W, Elbe-Burger A HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells. J. Exp. Med., 2009-01-12;206(1):169-81. 2009-01-12 [PMID: 19139172] (Human)		Human
Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22. J. Interferon Cytokine Res., 2008-05-01;28(5):297-310. 2008-05-01 [PMID: 18547160] (Human)		Human
Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. J. Neuroimmunol., 2008-06-09;199(1):35-45. 2008-06-09 [PMID: 18538864] (Human)		Human
Haas J, Schopp L, Storch-Hagenlocher B, Fritzsching B, Jacobi C, Milkova L, Fritz B, Schwarz A, Suri-Payer E, Hensel M, Wildemann B Specific recruitment of regulatory T cells into the CSF in lymphomatous and carcinomatous meningitis. Blood, 2007-10-29;111(2):761-6. 2007-10-29 [PMID: 17967942] (Human)		Human
Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc. Natl. Acad. Sci. U.S.A., 2007-02-05;104(7):2319-24. 2007-02-05 [PMID: 17283337] (Human)		Human
Borrelli V, di Marzo L, Sapienza P, Colasanti M, Moroni E, Cavallaro A Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions. Surgery, 2006-09-01;140(3):454-63. 2006-09-01 [PMID: 16934609] (Human)		Human
Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands. J. Immunol., 2006-05-15;176(10):5760-71. 2006-05-15 [PMID: 16670281] (Human)		Human
Hartl D, Latzin P, Zissel G, Krane M, Krauss-Etschmann S, Griese M Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Am. J. Respir. Crit. Care Med., 2006-03-16;173(12):1370-6. 2006-03-16 [PMID: 16543550] (Human)		Human
Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. Am. J. Respir. Crit. Care Med., 2004-06-10;170(5):508-15. 2004-06-10 [PMID: 15191918] (Human)		Human
Leung TF, Wong GW, Ko FW, Lam CW, Fok TF Increased macrophage-derived chemokine in exhaled breath condensate and plasma from children with asthma. Clin. Exp. Allergy, 2004-05-01;34(5):786-91. 2004-05-01 [PMID: 15144472] (Human)		Human
Hon KL, Leung TF, Ma KC, Li AM, Wong Y, Fok TF Serum levels of cutaneous T-cell attracting chemokine (CTACK) as a laboratory marker of the severity of atopic dermatitis in children. Clin. Exp. Dermatol., 2004-05-01;29(3):293-6. 2004-05-01 [PMID: 15115514] (Human)		Human
Leung TF, Ng PC, Tam WH, Li CY, Wong E, Ma TP, Lam CW, Fok TF Helper T-lymphocyte-related chemokines in healthy newborns. Pediatr. Res., 2003-11-19;55(2):334-8. 2003-11-19 [PMID: 14630994] (Human)		Human
Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J. Leukoc. Biol., 2001-10-01;70(4):617-23. 2001-10-01 [PMID: 11590199] (Human)		Human
Thompson SD, Luyrink LK, Graham TB, Tsoras M, Ryan M, Passo MH, Glass DN Chemokine receptor CCR4 on CD4+ T cells in juvenile rheumatoid arthritis synovial fluid defines a subset of cells with increased IL-4:IFN-gamma mRNA ratios. J. Immunol., 2001-06-01;166(11):6899-906. 2001-06-01 [PMID: 11359851] (Human)		Human
de Lavareille A, Roufosse F, Schandene L, Stordeur P, Cogan E, Goldman M Clonal Th2 cells associated with chronic hypereosinophilia: TARC-induced CCR4 down-regulation in vivo. Eur. J. Immunol., 2001-04-01;31(4):1037-46. 2001-04-01 [PMID: 11298328] (Human)		Human
Show All 31 Publications. Collapse Publications.

Array DMD00

• CCL22/MDC Antibodies
• CCL22/MDC Lysate
• CCL22/MDC Proteins
• CCL22/MDC Proteins and Enzymes
• CCL22/MDC ELISAs