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Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate

 (77 Publications)
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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price
HRP
PMMA00
HRP
SMMA00
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Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse MIP-1 alpha Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MIP-1 alpha levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse MIP-1 alpha and antibodies raised against the recombinant protein. Results obtained for naturally occurring mouse MIP-1 alpha showed linear curves that were parallel to the stan...dard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural mouse MIP-1 alpha.
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Specificity
Natural and recombinant mouse MIP-1 alpha
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL3

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
MMA00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate

  • C-C motif chemokine 3
  • MIP1-(a)
  • AI323804
  • CCL3
  • chemokine (C-C motif) ligand 3
  • G0S19-1
  • LD78a
  • LD78alpha
  • MIP1 alpha
  • MIP-1 alpha
  • MIP1A
  • MIP-1alpha
  • MIP1-alpha
  • PAT 464.1
  • SCYA3
  • SIS-beta

Background

MIP-1 alpha (macrophage inflammatory protein 1 alpha) is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils.

The two human MIP-1 alpha genes arise by duplication/mutation. They code for MIP-1 alpha isoforms CCL3/LD78a and CCL3L1/LD78b, which share 94% amino acid sequence homology. Whereas the human CCL3/LD78a is a single-copy gene, the human CCL3L1/LD78b gene copy number varies within the population. Human CCL3L1/LD78b binds and signals through chemokine receptors CCR1, CCR5. When compared to CCL3/LD78a, CCL3L1/LD78b has higher binding affinity to CCR5, which also functions as a coreceptor for HIV-1 entry. The copy number of CCL3L1 is one of several genetic determinants of HIV-1 susceptibility.

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Mouse CCL3/MIP-1
alpha Quantikine ELIS ...
MMA00
Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate
Species: Mu
Applications: ELISA
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL3/MIP-1 alpha (MMA00)(77)

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


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Mouse
(76)
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Showing Publications 1 - 10 of 77. Show All 77 Publications.
Publications using MMA00 Applications Species
Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q; LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis Cell reports 2023-08-11 [PMID: 37573508] (Mouse) Mouse
Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation International journal of biological sciences, 2022-08-08;18(13):5168-5184. 2022-08-08 [PMID: 35982894] (Mouse) Mouse
Y Ishihara, T Honda, N Ishihara, K Namba, M Taketoshi, Y Tominaga, M Tsuji, CFA Vogel, T Yamazaki, K Itoh, T Tominaga A CCR5 antagonist, maraviroc, alleviates neural circuit dysfunction and behavioral disorders induced by prenatal valproate exposure Journal of Neuroinflammation, 2022-07-29;19(1):195. 2022-07-29 [PMID: 35906621] (Mouse) Mouse
P Bhattachar, N Ismail, A Saxena, S Gannavaram, R Dey, T Oljuskin, A Akue, K Takeda, J Yu, S Karmakar, PK Dagur, JP McCoy, HL Nakhasi Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity PloS Neglected Tropical Diseases, 2022-02-22;16(2):e0010224. 2022-02-22 [PMID: 35192633] (Mouse) Mouse
Y Yuxiong, X Xujin, T Yi, C Ya, L Yujuan, H Shanshan, W Huiwen Brain-specific TRAF7 deletion ameliorates traumatic brain injury by suppressing MEKK3-regulated glial inflammation and neuronal death International immunopharmacology, 2021-12-23;103(0):108219. 2021-12-23 [PMID: 34953447] (Transgenic Mouse) Transgenic Mouse
K Tajiri, K Imanaka-Yo, Y Tsujimura, K Matsuo, M Hiroe, K Aonuma, M Ieda, Y Yasutomi A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Gu�rin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-&alpha International Journal of Molecular Sciences, 2021-01-14;22(2):. 2021-01-14 [PMID: 33466825] (Mouse) Mouse
R Morales, C Duran-Anio, J Bravo-Aleg, LD Estrada, M Shahnawaz, PP Hu, C Kramm, D Morales-Sc, A Urayama, C Soto Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease Acta neuropathologica communications, 2020-12-07;8(1):213. 2020-12-07 [PMID: 33287898] (Mouse) Mouse
M Kist, LG K?m?ves, T Goncharov, DL Dugger, C Yu, M Roose-Girm, K Newton, JD Webster, D Vucic Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death Cell Death Differ, 2020-09-30;0(0):. 2020-09-30 [PMID: 32999468] (Mouse) Mouse
K Taniguchi, Y Ando, H Nobori, S Toba, T Noshi, M Kobayashi, M Kawai, R Yoshida, A Sato, T Shishido, A Naito, K Matsuno, M Okamatsu, Y Sakoda, H Kida Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil Sci Rep, 2019-03-05;9(1):3466. 2019-03-05 [PMID: 30837531] (Mouse) Mouse
N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells JCI Insight, 2019-03-07;0(0):. 2019-03-07 [PMID: 30720466] (Mouse) Mouse
Show All 77 Publications.

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Bioinformatics

Gene Symbol CCL3