CCR7 Antibody (150503) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CCR7 (Chemokine Receptor 7; also CD197) is a 7 transmembrane (7TM) G protein-coupled chemokine receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine. CCL19 and CCL21 are constitutively expressed by high endothelial venule epithelial cells or fibroblastic reticular cells in secondary lymphoid organs. CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK cells, and B cells following inflammatory stimulation. Its expression enables the function of immune cell trafficking to and retention in regional lymph nodes for expansion of the adaptive immune response. Human CCR7 shares 87% amino acid sequence identity with mouse CCR7.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 9 confirmed species: Human, Mouse, Canine, Complex Species Category, Marmoset, Primate, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Primate - Macaca mulatta (Rhesus Macaque), Rabbit.

We have publications tested in 10 applications: Blocking, CyTof, Flow Cytometry, Flow Cytometry (CAR-T), Functional Assay, ICC, IHC, IHC-P, Neutralization, Western Blot.

Showing Publications 1 - 10 of 103. Show All 103 Publications. Collapse Publications.

Publications using MAB197	Applications	Species
Varco-Merth, B;Chaunzwa, M;Duell, DM;Marenco, A;Goodwin, W;Dannay, R;Nekorchuk, M;Shao, D;Busman-Sahay, K;Fennessey, CM;Silipino, L;Hull, M;Bosche, WJ;Fast, R;Oswald, K;Shoemaker, R;Bochart, R;MacAllister, R;Labriola, CS;Smedley, JV;Axthelm, MK;Davenport, MP;Edlefsen, PT;Estes, JD;Keele, BF;Lifson, JD;Lewin, SR;Picker, LJ;Okoye, AA; Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence PLoS pathogens 2024-08-01 [PMID: 39173097] (Flow Cytometry, Human)	Flow Cytometry	Human
Manami Toriyama, Defri Rizaldy, Motoki Nakamura, Yukiko Atsumi, Michinori Toriyama, Fumitaka Fujita et al. Corrigendum: Dendritic cell proliferation by primary cilium in atopic dermatitis Frontiers in Molecular Biosciences 8/30/2023 [PMID: 37711386]
Manami Toriyama, Defri Rizaldy, Motoki Nakamura, Yukiko Atsumi, Michinori Toriyama, Fumitaka Fujita et al. Dendritic cell proliferation by primary cilium in atopic dermatitis Frontiers in Molecular Biosciences 4/26/2023 [PMID: 37179569]
M Oba, Y Nakanishi, T Mitsuhashi, K Sasaki, KC Hatanaka, M Sasaki, A Nange, A Okumura, M Hayashi, Y Yoshida, T Nitta, T Ueno, T Yamada, M Ono, S Kuwabara, K Okamura, T Tsuchikawa, T Nakamura, T Noji, T Asano, K Tanaka, K Takayama, Y Hatanaka, S Hirano CCR7 Mediates Cell Invasion and Migration in Extrahepatic Cholangiocarcinoma by Inducing Epithelial-Mesenchymal Transition Cancers, 2023-03-21;15(6):. 2023-03-21 [PMID: 36980764] (Neutralization, Human)	Neutralization	Human
Ning Shao, Yufu Zhou, Jun Yao, Pengchao Zhang, Yanni Song, Kai Zhang et al. A Bidirectional Single‐Cell Migration and Retrieval Chip for Quantitative Study of Dendritic Cell Migration Advanced Science 3/1/2023 [PMID: 36658690]
Daniel Malouli, Roxanne M. Gilbride, Helen L. Wu, Joseph M. Hwang, Nicholas Maier, Colette M. Hughes et al. Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species Cell Host & Microbe 9/1/2022 [PMID: 35981532]
Dorien Feyaerts, Julien Hédou, Joshua Gillard, Han Chen, Eileen S. Tsai, Laura S. Peterson et al. Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19 Cell Reports Medicine 7/1/2022 [PMID: 35839768]
SA Rahman, J Billinglsl, AA Sharma, TM Styles, S Govindaraj, U Shanmugasu, H Babu, SP Ribeiro, SA Ali, GK Tharp, C Ibegbu, S Waggoner, RP Johnson, RP Sékaly, F Villinger, SE Bosinger, RR Amara, V Velu Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection JCI Insight, 2022-04-22;0(0):. 2022-04-22 [PMID: 35271506] (Flow Cytometry, Human)	Flow Cytometry	Human
Haruko Hayasaka, Junichi Yoshida, Yasutaka Kuroda, Akihiro Nishiguchi, Michiya Matsusaki, Kei Kishimoto et al. CXCL12 promotes CCR7 ligand–mediated breast cancer cell invasion and migration toward lymphatic vessels Cancer Science 4/1/2022 [PMID: 35133060]
AA Okoye, R Fromentin, H Takata, JH Brehm, Y Fukazawa, B Randall, M Pardons, V Tai, J Tang, J Smedley, M Axthelm, JD Lifson, LJ Picker, D Favre, L Trautmann, N Chomont The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription PloS Pathogens, 2022-01-18;18(1):e1010245. 2022-01-18 [PMID: 35041707] (ICC, Human)	ICC	Human
I Del Molino, A Meeson, K Cooke, MI Malki, B Barron-Mil, JA Kirby, S Ali Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells Cancers, 2021-07-10;13(14):. 2021-07-10 [PMID: 34298676] (ICC, IHC, Human)	ICC, IHC	Human
FY Mao, YP Lv, CJ Hao, YS Teng, YG Liu, P Cheng, SM Yang, W Chen, T Liu, QM Zou, R Xie, JY Xu, Y Zhuang Helicobacter pylori-induced Rev-erb&alpha fosters gastric bacteria colonization by impairing host innate and adaptive defense Cellular and Molecular Gastroenterology and Hepatology, 2021-03-03;0(0):. 2021-03-03 [PMID: 33676046] (Neutralization, Human)	Neutralization	Human
Afam A. Okoye, Derick D. Duell, Yoshinori Fukazawa, Benjamin Varco-Merth, Alejandra Marenco, Hannah Behrens et al. CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification Journal of Clinical Investigation 4/15/2021 [PMID: 33630764]
A Jerram, TV Guy, L Beutler, B Gunasegara, R Sluyter, B Fazekas de, HM McGuire Effects of storage time and temperature on highly multiparametric flow analysis of peripheral blood samples; implications for clinical trial samples Bioscience Reports, 2021-02-26;41(2):. 2021-02-26 [PMID: 33600563] (CyTof, Human)	CyTof	Human
JA van Ipenbu, NE de Waard, NC Naus, MJ Jager, D Paridaens, RM Verdijk Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions Invest. Ophthalmol. Vis. Sci., 2019-07-01;60(8):2950-2957. 2019-07-01 [PMID: 31305861] (IHC-P, Human)	IHC-P	Human
Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash et al. Development and application of a high-content virion display human GPCR array Nature Communications 4/30/2019 [PMID: 31040288]
Q Haas, K Frias Boli, C Jandus, C Schneider, C Simillion, MA Stanczak, M Haubitz, SM Seyed Jafa, A Zippelius, GM Baerlocher, H Läubli, RE Hunger, P Romero, HU Simon, S von Gunten Siglec-9 regulates an effector memory CD8+ T-cell subset that congregates in the melanoma tumor microenvironment Cancer Immunol Res, 2019-04-15;0(0):. 2019-04-15 [PMID: 30988027] (Flow Cytometry, Human)	Flow Cytometry	Human
AA Okoye, SG Hansen, M Vaidya, Y Fukazawa, H Park, DM Duell, R Lum, CM Hughes, AB Ventura, E Ainslie, JC Ford, D Morrow, RM Gilbride, AW Legasse, J Hesselgess, R Geleziunas, Y Li, K Oswald, R Shoemaker, R Fast, WJ Bosche, BR Borate, PT Edlefsen, MK Axthelm, LJ Picker, JD Lifson Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound Nat. Med., 2018-08-06;0(0):. 2018-08-06 [PMID: 30082858] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
T Alexander, Q Cheng, J Klotsche, L Khodadadi, A Waka, R Biesen, BF Hoyer, GR Burmester, A Radbruch, F Hiepe Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors Eur. J. Immunol., 2018-07-30;0(0):. 2018-07-30 [PMID: 29979809] (Flow Cytometry, Human)	Flow Cytometry	Human
N Jouand, C Bressollet, N Gérard, M Giral, P Guérif, A Rodallec, R Oger, T Parrot, M Allard, A Cesbron-Ga, N Gervois, B Charreau HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition PLoS Pathog., 2018-04-30;14(4):e1007041. 2018-04-30 [PMID: 29709038] (Flow Cytometry, Human)	Flow Cytometry	Human
D Kobayashi, M Endo, H Ochi, H Hojo, M Miyasaka, H Hayasaka Regulation of CCR7-dependent cell migration through�CCR7 homodimer formation Sci Rep, 2017-08-17;7(1):8536. 2017-08-17 [PMID: 28819198] (ICC, Human)	ICC	Human
M Mata, C Gerken, P Nguyen, G Krenciute, DM Spencer, S Gottschalk Inducible activation of MyD88 and CD40 in CAR T-cells results in controllable and potent antitumor activity in preclinical solid tumor models Cancer Discov, 2017-08-11;0(0):. 2017-08-11 [PMID: 28801306] (Flow Cytometry, Human)	Flow Cytometry	Human
JMJ Van den Be, ELJM Smits, M Versteven, H De Reu, ZN Berneman, VFI Van Tendel, E Lion Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use J Immunol Res, 2017-07-13;2017(0):1975902. 2017-07-13 [PMID: 28785596] (Flow Cytometry, Human)	Flow Cytometry	Human
F Bellora, A Dondero, MV Corrias, B Casu, S Regis, F Caliendo, A Moretta, M Cazzola, C Elena, L Vinti, F Locatelli, C Bottino, R Castriconi Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages J. Immunol., 2017-07-12;0(0):. 2017-07-12 [PMID: 28701512] (Flow Cytometry, Human)	Flow Cytometry	Human
L Huang, NHR Litjens, NM Kannegiete, M Klepper, CC Baan, MGH Betjes pERK-dependent defective TCR-mediated activation of CD4(+) T cells in end-stage renal disease patients Immun Ageing, 2017-06-19;14(0):14. 2017-06-19 [PMID: 28642802] (Flow Cytometry, Human)	Flow Cytometry	Human
SM Nguyen, KM Antony, DM Dudley, S Kohn, HA Simmons, B Wolfe, MS Salamat, LBC Teixeira, GJ Wiepz, TH Thoong, MT Aliota, AM Weiler, GL Barry, KL Weisgrau, LJ Vosler, MS Mohns, ME Breitbach, LM Stewart, MN Rasheed, CM Newman, ME Graham, OE Wieben, PA Turski, KM Johnson, J Post, JM Hayes, N Schultz-Da, ML Schotzko, JA Eudailey, SR Permar, EG Rakasz, EL Mohr, S Capuano, AF Tarantal, JE Osorio, SL O'Connor, TC Friedrich, DH O'Connor, TG Golos Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques PLoS Pathog., 2017-05-25;13(5):e1006378. 2017-05-25 [PMID: 28542585] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Z Zhang, F Liu, Z Li, D Wang, R Li, C Sun Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck Oncol Lett, 2017-03-14;13(5):3191-3197. 2017-03-14 [PMID: 28521425] (Neutralization, Human)	Neutralization	Human
FG Karnell, D Lin, S Motley, T Duhen, N Lim, DJ Campbell, LA Turka, HT Maecker, KM Harris Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation Clin. Exp. Immunol., 2017-06-07;0(0):. 2017-06-07 [PMID: 28498568] (CyTof, Human)	CyTof	Human
J Dunham, N van Driel, BJ Eggen, C Paul, BA 't Hart, JD Laman, YS Kap Analysis of the cross-talk of Epstein-Barr virus-infected B cells with T cells in the marmoset Clin Transl Immunology, 2017-02-10;6(2):e127. 2017-02-10 [PMID: 28243437] (Flow Cytometry, Primate)	Flow Cytometry	Primate
T Koya, R Yanagisawa, Y Higuchi, K Sano, S Shimodaira Interferon-?-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity Sci Rep, 2017-02-13;7(0):42145. 2017-02-13 [PMID: 28191816] (Flow Cytometry, Human)	Flow Cytometry	Human
S Pichyangku, MD Spring, K Yongvanitc, U Kum-Arb, A Limsalakpe, R Im-Erbsin, R Ubalee, P Vanachayan, EJ Remarque, E Angov, PL Smith, DL Saunders Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver PLoS ONE, 2017-02-09;12(2):e0171826. 2017-02-09 [PMID: 28182750] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction Nat Commun, 2016-12-23;7(0):13895. 2016-12-23 [PMID: 28008916] (Flow Cytometry, Human)	Flow Cytometry	Human
Vassilios Lougaris NFKB1 regulates human NK cell maturation and effector functions Clin. Immunol, 2016-12-03;0(0):. 2016-12-03 [PMID: 27923702] (Flow Cytometry, Human)	Flow Cytometry	Human
Evan W Newell Optimization of mass cytometry sample cryopreservation after staining Cytometry A, 2016-10-31;0(0):. 2016-10-31 [PMID: 27798817] (CyTof, Human)	CyTof	Human
Roger Geiger, Jan C. Rieckmann, Tobias Wolf, Camilla Basso, Yuehan Feng, Tobias Fuhrer et al. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity Cell 10/20/2016 [PMID: 27745970]
Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs PLoS Pathog, 2016-08-19;12(8):e1005799. 2016-08-19 [PMID: 27540722] (Flow Cytometry, Human)	Flow Cytometry	Human
Dengue virus infection induces interferon-lambda1 to facilitate cell migration Sci Rep, 2016-07-26;6(0):24530. 2016-07-26 [PMID: 27456172] (Flow Cytometry, Human)	Flow Cytometry	Human
Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5 J Immunol, 2016-05-13;0(0):. 2016-05-13 [PMID: 27183609] (Flow Cytometry, Human)	Flow Cytometry	Human
CF Kelley, L Lai, C Ibegbu, ES Rosenberg, S Kaur, K Patel, MJ Mulligan, VC Marconi, PS Sullivan, RR Amara Differences in expression of gut-homing receptors on CD4+ T cells in black and white HIV-negative men who have sex with men AIDS, 2016-05-15;30(8):1305-8. 2016-05-15 [PMID: 26891038] (Flow Cytometry, Human)	Flow Cytometry	Human
Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, Duell D, Sylwester A, Sammader P, Legasse A, Park B, Axthelm M, Nikolich-Zugich J, Picker L Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques. J Immunol, 2015-09-28;195(9):4292-305. 2015-09-28 [PMID: 26416281] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Pichyangkul S, Yongvanitchit K, Limsalakpetch A, Kum-Arb U, Im-Erbsin R, Boonnak K, Thitithayanont A, Jongkaewwattana A, Wiboon-ut S, Mongkolsirichaikul D, Mahanonda R, Spring M, Chuang I, Mason C, Saunders D Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection. J Immunol, 2015-09-25;195(9):4378-86. 2015-09-25 [PMID: 26408671] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
White M, Gomer R Trypsin, Tryptase, and Thrombin Polarize Macrophages towards a Pro-Fibrotic M2a Phenotype. PLoS ONE, 2015-09-25;10(9):e0138748. 2015-09-25 [PMID: 26407067] (IHC, Human)	IHC	Human
Patrussi L, Capitani N, Martini V, Pizzi M, Trimarco V, Frezzato F, Marino F, Semenzato G, Trentin L, Baldari C Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia. Cancer Res, 2015-08-17;75(19):4153-63. 2015-08-17 [PMID: 26282174] (Flow Cytometry, Human)	Flow Cytometry	Human
Pesce S, Carlomagno S, Moretta A, Sivori S, Marcenaro E Uptake of CCR7 by KIR2DS4(+) NK cells is induced upon recognition of certain HLA-C alleles. J Immunol Res, 2015-04-16;2015(0):754373. 2015-04-16 [PMID: 25961063] (Flow Cytometry, Human)	Flow Cytometry	Human
Jacomet F, Cayssials E, Basbous S, Levescot A, Piccirilli N, Desmier D, Robin A, Barra A, Giraud C, Guilhot F, Roy L, Herbelin A, Gombert J Evidence for eomesodermin-expressing innate-like CD8(+) KIR/NKG2A(+) T cells in human adults and cord blood samples. Eur J Immunol, 2015-05-20;45(7):1926-33. 2015-05-20 [PMID: 25903796] (Flow Cytometry, Human)	Flow Cytometry	Human
Mei H, Leipold M, Schulz A, Chester C, Maecker H Barcoding of live human peripheral blood mononuclear cells for multiplexed mass cytometry. J Immunol, 2015-01-21;194(4):2022-31. 2015-01-21 [PMID: 25609839] (CyTof, Human)	CyTof	Human
Hui-Ling Huang, Chi-Hsiang Chiang, Wen-Chun Hung, Ming-Feng Hou Targeting of TGF-beta -activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Oncotarget 1/20/2015 [PMID: 25557171]
Takakura K, Koido S, Kan S, Yoshida K, Mori M, Hirano Y, Ito Z, Kobayashi H, Takami S, Matsumoto Y, Kajihara M, Misawa T, Okamoto M, Sugiyama H, Homma S, Ohkusa T, Tajiri H Prognostic markers for patient outcome following vaccination with multiple MHC Class I/II-restricted WT1 peptide-pulsed dendritic cells plus chemotherapy for pancreatic cancer. Anticancer Res, 2015-01-01;35(1):555-62. 2015-01-01 [PMID: 25550602] (Flow Cytometry, Human)	Flow Cytometry	Human
Williams G, Pachnio A, Long H, Rauz S, Curnow S Cytokine production and antigen recognition by human mucosal homing conjunctival effector memory CD8+ T cells. Invest Ophthalmol Vis Sci, 2014-11-13;55(12):8523-30. 2014-11-13 [PMID: 25395484] (Flow Cytometry, Human)	Flow Cytometry	Human
Xuan W, Qu Q, Zheng B, Xiong S, Fan G The chemotaxis of M1 and M2 macrophages is regulated by different chemokines. J Leukoc Biol, 2014-10-30;97(1):61-9. 2014-10-30 [PMID: 25359998] (Neutralization, Human)	Neutralization	Human
SHI-XIA LIAO, TING DING, XI-MIN RAO, DE-SHENG SUN, PENG-PENG SUN, YA-JUN WANG et al. Cigarette smoke affects dendritic cell maturation in the small airways of patients with chronic obstructive pulmonary disease Molecular Medicine Reports 1/1/2015 [PMID: 25338516]
Schanz A, Red-Horse K, Hess A, Baston-Bust D, Heiss C, Krussel J Oxygen regulates human cytotrophoblast migration by controlling chemokine and receptor expression. Placenta, 2014-09-26;35(12):1089-94. 2014-09-26 [PMID: 25293376] (Western Blot, Human)	Western Blot	Human
Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun, 2014-09-02;5(0):4715. 2014-09-02 [PMID: 25178650] (Blocking, Human)	Blocking	Human
Antsiferova O, Muller A, Ramer P, Chijioke O, Chatterjee B, Raykova A, Planas R, Sospedra M, Shumilov A, Tsai M, Delecluse H, Munz C Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice. PLoS Pathog, 2014-08-28;10(8):e1004333. 2014-08-28 [PMID: 25165855] (Flow Cytometry, Human)	Flow Cytometry	Human
Rasul E, Salamon D, Nagy N, Leveau B, Banati F, Szenthe K, Koroknai A, Minarovits J, Klein G, Klein E The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia. PLoS ONE, 2014-08-27;9(8):e106008. 2014-08-27 [PMID: 25162594] (Flow Cytometry, Human)	Flow Cytometry	Human
Campion S, Brodie T, Fischer W, Korber B, Rossetti A, Goonetilleke N, McMichael A, Sallusto F Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors. J Exp Med, 2014-06-23;211(7):1273-80. 2014-06-23 [PMID: 24958850] (Flow Cytometry, Human)	Flow Cytometry	Human
Borgman K, van Zanten T, Manzo C, Cabezon R, Cambi A, Benitez-Ribas D, Garcia-Parajo M Priming by chemokines restricts lateral mobility of the adhesion receptor LFA-1 and restores adhesion to ICAM-1 nano-aggregates on human mature dendritic cells. PLoS ONE, 2014-06-19;9(6):e99589. 2014-06-19 [PMID: 24945611] (Flow Cytometry, Human)	Flow Cytometry	Human
Xu Y, Zhang M, Ramos C, Durett A, Liu E, Dakhova O, Liu H, Creighton C, Gee A, Heslop H, Rooney C, Savoldo B, Dotti G Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15. Blood, 2014-04-29;123(24):3750-9. 2014-04-29 [PMID: 24782509] (Flow Cytometry (CAR-T), Human)	Flow Cytometry (CAR-T)	Human
Kap , Yolanda, van Driel , Nikki, Laman , Jon D, Tak , Paul P, 't Hart , Bert A CD20+ B cell depletion alters T cell homing. J Immunol, 2014-04-02;192(9):4242-53. 2014-04-02 [PMID: 24696233] (Flow Cytometry, Marmoset)	Flow Cytometry	Marmoset
Carrega , Paolo, Bonaccorsi , Irene, Di Carlo , Emma, Morandi , Barbara, Paul , Petra, Rizzello , Valeria, Cipollone , Giuseppe, Navarra , Giuseppe, Mingari , Maria Cr, Moretta , Lorenzo, Ferlazzo , Guido CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph. J Immunol, 2014-03-19;192(8):3805-15. 2014-03-19 [PMID: 24646734] (Flow Cytometry, Human)	Flow Cytometry	Human
Rongvaux , Anthony, Willinger , Tim, Martinek , Jan, Strowig , Till, Gearty , Sofia V, Teichmann , Lino L, Saito , Yasuyuki, Marches , Florenti, Halene , Stephani, Palucka , A Karoli, Manz , Markus G, Flavell , Richard Development and function of human innate immune cells in a humanized mouse model. Nat Biotechnol, 2014-03-16;32(4):364-72. 2014-03-16 [PMID: 24633240] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Pinto S, Martinez-Romero A, O'Connor J, Gil-Benso R, San-Miguel T, Terradez L, Monteagudo C, Callaghan R Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation. BMC Cancer, 2014-02-22;14(0):118. 2014-02-22 [PMID: 24559071] (ICC, Human)	ICC	Human
Ishikawa , Takeshi, Kokura , Satoshi, Enoki , Tatsuji, Sakamoto , Naoyuki, Okayama , Tetsuya, Ideno , Mitsuko, Mineno , Junichi, Uno , Kazuko, Yoshida , Naohisa, Kamada , Kazuhiro, Katada , Kazuhiro, Uchiyama , Kazuhiko, Handa , Osamu, Takagi , Tomohisa, Konishi , Hideyuki, Yagi , Nobuaki, Naito , Yuji, Itoh , Yoshito, Yoshikawa , Toshikaz Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer. PLoS ONE, 2014-01-31;9(1):e83786. 2014-01-31 [PMID: 24497917] (Flow Cytometry, Human)	Flow Cytometry	Human
Yin X, Johns S, Kim D, Mikulski Z, Salanga C, Handel T, Macal M, Zuniga E, Fuster M Lymphatic specific disruption in the fine structure of heparan sulfate inhibits dendritic cell traffic and functional T cell responses in the lymph node. J Immunol, 2014-02-03;192(5):2133-42. 2014-02-03 [PMID: 24493818] (Blocking, Human)	Blocking	Human
Somovilla-Crespo B, Alfonso-Perez M, Cuesta-Mateos C, Carballo-de Dios C, Beltran A, Terron F, Perez-Villar J, Gamallo-Amat C, Perez-Chacon G, Fernandez-Ruiz E, Zapata J, Munoz-Calleja C Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma. J Hematol Oncol, 2013-12-04;6(0):89. 2013-12-04 [PMID: 24305507] (Neutralization, Human)	Neutralization	Human
Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, Corrias M, Moretta A, Bottino C Neuroblastoma-derived TGF-beta1 modulates the chemokine receptor repertoire of human resting NK cells. J Immunol, 2013-04-10;190(10):5321-8. 2013-04-10 [PMID: 23576682] (Flow Cytometry, Human)	Flow Cytometry	Human
Manes , Thomas D, Pober , Jordan S TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA. J Immunol, 2013-02-18;190(7):3079-88. 2013-02-18 [PMID: 23420881] (Functional Assay, Human)	Functional Assay	Human
Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency. J Allergy Clin Immunol, 2013-02-10;131(4):1146-56, 1156. 2013-02-10 [PMID: 23403044] (Flow Cytometry, Human)	Flow Cytometry	Human
Santegoets S, Turksma A, Suhoski M, Stam A, Albelda S, Hooijberg E, Scheper R, van den Eertwegh A, Gerritsen W, Powell D, June C, de Gruijl T IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells. J Transl Med, 2013-02-12;11(0):37. 2013-02-12 [PMID: 23402380] (Flow Cytometry, Human)	Flow Cytometry	Human
Vacca P, Martini S, Garelli V, Passalacqua G, Moretta L, Mingari M NK cells from malignant pleural effusions are not anergic but produce cytokines and display strong antitumor activity on short-term IL-2 activation. Eur J Immunol, 2013-01-15;43(2):550-61. 2013-01-15 [PMID: 23192659] (Flow Cytometry, Human)	Flow Cytometry	Human
Duluc , D, Gannevat , J, Anguiano , E, Zurawski , S, Carley , M, Boreham , M, Stecher , J, Dullaers , M, Banchereau , J, Oh , S Functional diversity of human vaginal APC subsets in directing T-cell responses. Mucosal Immunol, 2012-11-07;6(3):626-38. 2012-11-07 [PMID: 23131784] (Flow Cytometry, Human)	Flow Cytometry	Human
Accelerated heterologous adenovirus prime-boost SIV vaccine in neonatal rhesus monkeys. Oncogene, 2012-05-16;86(15):7829-35. 2012-05-16 [PMID: 22593160] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature, 2012-04-26;484(7395):514-8. 2012-04-26 [PMID: 22466287] (Flow Cytometry, Human)	Flow Cytometry	Human
Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA Identification of human NK17/NK1 cells. PLoS ONE, 2011-10-21;6(10):e26780. 2011-10-21 [PMID: 22039549] (Flow Cytometry, Human)	Flow Cytometry	Human
Sun Jin Baek, Sung Keun Kang, Jeong Chan Ra In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors Experimental and Molecular Medicine 10/31/2011 [PMID: 21847008]
Sherry M. Farley, Lisa J. Wood, Mihail S. Iordanov An Epidermotypic Model of Interface Dermatitis Reveals Individual Functions of Fas Ligand and Gamma Interferon in Hypergranulosis, Cytoid Body Formation, and Gene Expression The American Journal of Dermatopathology 5/1/2011 [PMID: 21430507]
Islam SA, Chang DS, Colvin RA Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat. Immunol., 2011-01-09;12(2):167-77. 2011-01-09 [PMID: 21217759] (Flow Cytometry, Human)	Flow Cytometry	Human
Ansari AA, Reimann KA, Mayne AE, Takahashi Y, Stephenson ST, Wang R, Wang X, Li J, Price AA, Little DM, Zaidi M, Lyles R, Villinger F Blocking of alpha4beta7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J. Immunol., 2010-12-13;186(2):1044-59. 2010-12-13 [PMID: 21149598] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Julie Catusse, Marion Leick, Mareike Groch, David J Clark, Maike V Buchner, Katja Zirlik et al. Role of the atypical chemoattractant receptor CRAM in regulating CCL19 induced CCR7 responses in B-cell chronic lymphocytic leukemia Molecular Cancer 12/1/2010 [PMID: 21092185]
Antonelli LR, Mahnke Y, Hodge JN, Porter BO, Barber DL, DerSimonian R, Greenwald JH, Roby G, Mican J, Sher A, Roederer M, Sereti I Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. Blood, 2010-07-26;116(19):3818-27. 2010-07-26 [PMID: 20660788] (Flow Cytometry, Human)	Flow Cytometry	Human
Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M, Roederer M, Lifson JD, Ott DE, Ohlen C Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones in rhesus macaques during acute infection. J. Immunol., 2009-11-30;184(1):315-26. 2009-11-30 [PMID: 19949091] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M, O'Connor D, Lifson JD, Roederer M, Ohlen C Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. J. Immunol., 2009-11-30;184(1):303-14. 2009-11-30 [PMID: 19949089] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Yu J, Mao HC, Wei M, Hughes T, Zhang J, Park IK, Liu S, McClory S, Marcucci G, Trotta R, Caligiuri MA CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood, 2009-11-06;115(2):274-81. 2009-11-06 [PMID: 19897577] (Flow Cytometry, Human)	Flow Cytometry	Human
Berrih-Aknin S, Ruhlmann N, Bismuth J, Cizeron-Clairac G, Zelman E, Shachar I, Dartevelle P, de Rosbo NK, Le Panse R CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia. Ann. Neurol., 2009-10-01;66(4):521-31. 2009-10-01 [PMID: 19847900] (Flow Cytometry, Human)	Flow Cytometry	Human
Birke K, Lutjen-Drecoll E, Kerjaschki D, Birke MT Expression of podoplanin and other lymphatic markers in the human anterior eye segment. Invest. Ophthalmol. Vis. Sci., 2009-09-08;51(1):344-54. 2009-09-08 [PMID: 19737877] (IHC, Human)	IHC	Human
Brusa D, Garetto S, Chiorino G, Scatolini M, Migliore E, Camussi G, Matera L Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity. Vaccine, 2008-10-09;26(50):6422-32. 2008-10-09 [PMID: 18848858] (Flow Cytometry, Human)	Flow Cytometry	Human
Mason NJ, Coughlin CM, Overley B, Cohen JN, Mitchell EL, Colligon TA, Clifford CA, Zurbriggen A, Sorenmo KU, Vonderheide RH RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma. Gene Ther., 2008-03-13;15(13):955-65. 2008-03-13 [PMID: 18337841] (Flow Cytometry, Canine)	Flow Cytometry	Canine
Ali Z, Shao L, Halliday L, Reichenberg A, Hintz M, Jomaa H, Chen ZW Prolonged (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-driven antimicrobial and cytotoxic responses of pulmonary and systemic Vgamma2Vdelta2 T cells in macaques. J. Immunol., 2007-12-15;179(12):8287-96. 2007-12-15 [PMID: 18056373] (Flow Cytometry, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque))	Flow Cytometry	Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Yamanaka K, Dimitroff CJ, Fuhlbrigge RC, Kakeda M, Kurokawa I, Mizutani H, Kupper TS Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression. J. Allergy Clin. Immunol., 2007-10-01;121(1):148-157.e3. 2007-10-01 [PMID: 17910894] (Flow Cytometry, Human)	Flow Cytometry	Human
Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J. Immunol., 2007-09-15;179(6):3724-33. 2007-09-15 [PMID: 17785809] (Flow Cytometry, Human)	Flow Cytometry	Human
Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. J. Exp. Med., 2007-08-27;204(9):2171-85. 2007-08-27 [PMID: 17724130] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell, 2007-06-01;11(6):526-38. 2007-06-01 [PMID: 17560334] (IHC, Neutralization, Western Blot, Human)	IHC, Neutralization, Western Blot	Human
Andersen H, Barsov EV, Trivett MT, Trubey CM, Giavedoni LD, Lifson JD, Ott DE, Ohlen C Transduction with human telomerase reverse transcriptase immortalizes a rhesus macaque CD8+ T cell clone with maintenance of surface marker phenotype and function. AIDS Res. Hum. Retroviruses, 2007-03-01;23(3):456-65. 2007-03-01 [PMID: 17411379] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice. Am. J. Pathol., 2007-04-01;170(4):1152-64. 2007-04-01 [PMID: 17392156] (Neutralization, Complex Species Category)	Neutralization	Complex Species Category
Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Evanoff H, Flaherty KR, Martinez FJ, Toews GB, Hogaboam CM Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21. Eur. Respir. J., 2007-03-01;29(6):1082-93. 2007-03-01 [PMID: 17331965] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Ni Z, Campbell JJ, Niehans G, Walcheck B The monoclonal antibody CHO-131 identifies a subset of cutaneous lymphocyte-associated antigen T cells enriched in P-selectin-binding cells. J. Immunol., 2006-10-01;177(7):4742-8. 2006-10-01 [PMID: 16982914] (Flow Cytometry, Human)	Flow Cytometry	Human
Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J. Immunol., 2006-10-01;177(7):4488-94. 2006-10-01 [PMID: 16982885] (Flow Cytometry, Human)	Flow Cytometry	Human
Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int. J. Cancer, 2006-05-01;118(9):2147-57. 2006-05-01 [PMID: 16331601] (IHC, Human)	IHC	Human
Humphreys TL, Baldridge LA, Billings SD, Campbell JJ, Spinola SM Trafficking pathways and characterization of CD4 and CD8 cells recruited to the skin of humans experimentally infected with Haemophilus ducreyi. Infect. Immun., 2005-07-01;73(7):3896-902. 2005-07-01 [PMID: 15972475] (Flow Cytometry, Human)	Flow Cytometry	Human
Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, Beauplet A, Robillard N, Semana G Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression. Eur. J. Immunol., 2004-12-01;34(12):3485-96. 2004-12-01 [PMID: 15484187] (Flow Cytometry, Human)	Flow Cytometry	Human
Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis. Int. J. Oncol., 2004-09-01;25(3):605-13. 2004-09-01 [PMID: 15289861] (ICC, Human)	ICC	Human
Sinha RK, Mage RG Developing neonatal rabbit appendix, a primary lymphoid organ, is seeded by immature blood-borne B cells: evidence for roles for CD62L/PNAd, CCR7/CCL21, alpha4beta1 and LFA-1. Dev. Comp. Immunol., 2004-06-01;28(7):829-41. 2004-06-01 [PMID: 15043950] (Flow Cytometry, Rabbit)	Flow Cytometry	Rabbit
Doubrovina ES, Doubrovin MM, Vider E, Sisson RB, O'Reilly RJ, Dupont B, Vyas YM Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J. Immunol., 2003-12-15;171(12):6891-9. 2003-12-15 [PMID: 14662896] (Flow Cytometry, Human)	Flow Cytometry	Human
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	5 reviewed by: Verified Customer	IF	Human	02/12/2015	View Summary Application Immunofluorescence Sample Tested See PMID 23731727 Species Human

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