CRAT Antibody

Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The alternatively splicing of this gene results in three distinct isoforms, one of which contains an N-terminial mitochondrial transit peptide, and has been shown to be located in mitochondria.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: KD, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-86616	Applications	Species
Song MJ, Park CH, Kim H et al. Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction-induced cellular senescence in dermal fibroblasts Aging cell 2023-10-13 [PMID: 37828898] (WB, Human)	WB	Human
Lasheras-Otero I, Feliu I, Maillo A et al. The regulators of peroxisomal acyl-carnitine shuttle CROT and CRAT promote metastasis in melanoma Journal of Investigative Dermatology 2022-09-01 [PMID: 36058299] (KD, WB, Human) Details: Supplementary figure 4	KD, WB	Human

Array NBP1-86616

• CRAT Antibodies
• CRAT Lysates
• CRAT Proteins