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CCR2 Antibody [DyLight 755]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-48338AF350
Alexa Fluor 405
NBP1-48338AF405
Alexa Fluor 488
NBP1-48338AF488
Alexa Fluor 532
NBP1-48338AF532
Alexa Fluor 594
NBP1-48338AF594
Alexa Fluor 647
NBP1-48338AF647
Alexa Fluor 700
NBP1-48338AF700
Alexa Fluor 750
NBP1-48338AF750
Allophycocyanin
NBP1-48338APC
Allophycocyanin/Cy7
NBP1-48338APCCY7
Biotin
NBP1-48338B
CoraFluor 1
NBP1-48338CL1
DyLight 350
NBP1-48338UV
DyLight 405
NBP1-48338V
DyLight 488
NBP1-48338G
DyLight 550
NBP1-48338R
DyLight 594
NBP1-48338DL594
DyLight 650
NBP1-48338C
DyLight 680
NBP1-48338FR
FITC
NBP1-48338F
Janelia Fluor 525
NBP1-48338JF525
Janelia Fluor 549
NBP1-48338JF549
Janelia Fluor 585
NBP1-48338JF585
Janelia Fluor 635
NBP1-48338JF635
Janelia Fluor 646
NBP1-48338JF646
Janelia Fluor 669
NBP1-48338JF669
PE
NBP1-48338PE
PE/Atto594
NBP1-48338PEATT594
PE/Cy5.5
NBP1-48338PECY55
PE/Cy7
NBP1-48338PECY7
PerCP
NBP1-48338PCP
Unconjugated
NBP1-48338
mFluor Violet 450 SE
NBP1-48338MFV450
mFluor Violet 500 SE
NBP1-48338MFV500
mFluor Violet 610 SE
NBP1-48338MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-48338
BSA Free
NBP1-48338SS
BSA Free
NBP1-48338
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CCR2 Antibody [DyLight 755] Summary

Immunogen
Synthetic peptide made to an N-terminal portion of the mouse CCR2 protein (within residues 20-100). [Swiss-Prot# P51683]
Localization
Cell membrane; Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCR2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CCR2 Antibody [DyLight 755]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CCR2