| Rezvani, M;Lewis, K;Quach, S;Iwasawa, K;Weihs, J;Reza, H;Cai, Y;Kimura, M;Zhang, R;Milton, Y;Chaturvedi, P;Thorner, K;Nayak, RC;Munera, JO;Kramer, P;Davis, B;Balamurugan, A;Ait Ahmed, Y;Finke, M;Behncke, RY;Guillot, A;Haegerling, R;Polansky, J;Bufler, P;Cancelas, J;Wells, J;Yoshimoto, M;Takebe, T; Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells bioRxiv : the preprint server for biology 2024-10-12 [PMID: 39416072] (Bioassay, Human) |
Bioassay |
Human |
| Saotome, K;McGoldrick, LL;Ho, JH;Ramlall, TF;Shah, S;Moore, MJ;Kim, JH;Leidich, R;Olson, WC;Franklin, MC; Structural insights into CXCR4 modulation and oligomerization Nature structural & molecular biology 2024-09-23 [PMID: 39313635] (Bioassay, Human) |
Bioassay |
Human |
| Hayderi, A;Zegeye, MM;Meydan, S;Sirsjö, A;Kumawat, AK;Ljungberg, LU; TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype International journal of molecular sciences 2024-08-09 [PMID: 39201392] (Bioassay, Human) |
Bioassay |
Human |
| Portella, L;Bertolini, G;Guardascione, G;Di Febbraro, DG;Ieranò, C;D'Alterio, C;Rea, G;Napolitano, M;Santagata, S;Trotta, AM;Camerlingo, R;Scarpa, E;Cecere, SC;Ottaiano, A;Palumbo, G;Morabito, A;Somma, T;De Rosa, G;Mayol, L;Pacelli, R;Pignata, S;Scala, S; CXCL12-loaded-hydrogel (CLG): A new device for metastatic circulating tumor cells (CTCs) capturing and characterization Heliyon 2024-08-15 [PMID: 39170328] (Bioassay, Human) |
Bioassay |
Human |
| Zhou, Z;Guo, J;Hetrick, B;Tiwari, S;Haikerwal, A;Han, Y;Bond, VC;Huang, MB;Mankowski, MK;Snyder, BA;Hogan, PA;Sharma, SK;Liotta, DC;Reid, TE;Wilson, LJ;Wu, Y; Characterization of a CXCR4 antagonist TIQ-15 with dual tropic HIV entry inhibition properties PLoS pathogens 2024-08-15 [PMID: 39146384] (Bioassay, Hamster, Human) |
Bioassay |
Hamster, Human |
| Park, H;Song, J;Jeong, HW;Grönloh, MLB;Koh, BI;Bovay, E;Kim, KP;Klotz, L;Thistlethwaite, PA;van Buul, JD;Sorokin, L;Adams, RH; Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis Nature communications 2024-07-25 [PMID: 39060233] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Abello, J;Yin, Y;Zhao, Y;Maurer, J;Lee, J;Bodell, C;Clevenger, AJ;Burton, Z;Goeckel, ME;Lin, M;Grainger, S;Halabi, CM;Raghavan, SA;Sah, R;Stratman, AN; Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries bioRxiv : the preprint server for biology 2024-06-12 [PMID: 38915529] (Bioassay, Human) |
Bioassay |
Human |
| Johnson, D;Colijn, S;Richee, J;Yano, J;Burns, M;Davis, AE;Pham, VN;Saric, A;Jain, A;Yin, Y;Castranova, D;Melani, M;Fujita, M;Grainger, S;Bonifacino, JS;Weinstein, BM;Stratman, AN; Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1 bioRxiv : the preprint server for biology 2024-04-01 [PMID: 38903077] (Bioassay, Human) |
Bioassay |
Human |
| Raufi, AG;Pellicciotta, I;Palermo, CF;Sastra, SA;Chen, A;Alouani, E;Maurer, HC;May, M;Iuga, A;Rabadan, R;Olive, KP;Manji, GA; Cytotoxic chemotherapy potentiates the immune response and efficacy of combination CXCR4/PD-1 inhibition in models of pancreatic ductal adenocarcinoma bioRxiv : the preprint server for biology 2023-12-25 [PMID: 38234792] (Bioassay, Human) |
Bioassay |
Human |
| Schumacher, JA;Wright, ZA;Rufin Florat, D;Anand, SK;Dasyani, M;Batta, SPR;Laverde, V;Ferrari, K;Klimkaite, L;Bredemeier, NO;Gurung, S;Koller, GM;Aguera, KN;Chadwick, GP;Johnson, RD;Davis, GE;Sumanas, S; SH2 domain protein E and ABL signaling regulate blood vessel size PLoS genetics 2024-01-08 [PMID: 38190417] (Bioassay, Human) |
Bioassay |
Human |
| Lyu, H;Shen, F;Ruan, S;Tan, C;Zhou, J;Thor, AD;Liu, B; HER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel Cancer cell international 2023-09-16 [PMID: 37716943] (Bioassay, Human) |
Bioassay |
Human |
| Lim, HJ;Jang, WB;Rethineswaran, VK;Choi, J;Lee, EJ;Park, S;Jeong, Y;Ha, JS;Yun, J;Choi, YJ;Hong, YJ;Kwon, SM; StemRegenin-1 Attenuates Endothelial Progenitor Cell Senescence by Regulating the AhR Pathway-Mediated CYP1A1 and ROS Generation Cells 2023-08-05 [PMID: 37566085] (Bioassay, Human) |
Bioassay |
Human |
| Toffali, L;D'Ulivo, B;Giagulli, C;Montresor, A;Zenaro, E;Delledonne, M;Rossato, M;Iadarola, B;Sbarbati, A;Bernardi, P;Angelini, G;Rossi, B;Lopez, N;Linke, WA;Unger, A;Di Silvestre, D;Benazzi, L;De Palma, A;Motta, S;Constantin, G;Mauri, P;Laudanna, C; An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking Cell reports 2023-05-18 [PMID: 37204926] (Bioassay, Human) |
Bioassay |
Human |
| Shariatzadeh, M;Nagtzaam, NMA;van Vark-van der Zee, L;van Holten-Neelen, C;Verhoeven, AJM;Dehairs, J;Swinnen, JV;Leijten, F;Ten Berge, JC;Ciriano, JPM;Wong, KT;Mulder, M;Leenen, PJM;Dik, WA; Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy Investigative ophthalmology & visual science 2023-05-01 [PMID: 37159194] (Bioassay, Human) |
Bioassay |
Human |
| YH Lai, CY Su, HW Cheng, CY Chu, LB Jeng, CS Chiang, WC Shyu, SY Chen Stem cell-nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy Nature Communications, 2023-01-18;14(1):285. 2023-01-18 [PMID: 36650171] (Bioassay, Human) |
Bioassay |
Human |
| M Tobiume, A Mitsuhashi, A Saijo, H Ogino, T Afroj, H Ogawa, H Goto, S Sato, A Abe, K Haji, R Ozaki, H Takizawa, Y Nishioka Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer Oncology Letters, 2022-09-30;24(5):417. 2022-09-30 [PMID: 36245829] (Bioassay, Human) |
Bioassay |
Human |
| X Yuan, H Wu, X Li, L Chen, Y Xiao, Z Chen, G Liu, P Lu SDF?1alpha/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways in�vitro Molecular Medicine Reports, 2022-08-10;26(4):. 2022-08-10 [PMID: 35946444] (Bioassay, Human) |
Bioassay |
Human |
| H Namkoong, R Edahiro, T Takano, H Nishihara, Y Shirai, K Sonehara, H Tanaka, S Azekawa, Y Mikami, H Lee, T Hasegawa, K Okudela, D Okuzaki, D Motooka, M Kanai, T Naito, K Yamamoto, QS Wang, R Saiki, R Ishihara, Y Matsubara, J Hamamoto, H Hayashi, Y Yoshimura, N Tachikawa, E Yanagita, T Hyugaji, E Shimizu, K Katayama, Y Kato, T Morita, K Takahashi, N Harada, T Naito, M Hiki, Y Matsushita, H Takagi, R Aoki, A Nakamura, S Harada, H Sasano, H Kabata, K Masaki, H Kamata, S Ikemura, S Chubachi, S Okamori, H Terai, A Morita, T Asakura, J Sasaki, H Morisaki, Y Uwamino, K Nanki, S Uchida, S Uno, T Nishimura, T Ishiguro, T Isono, S Shibata, Y Matsui, C Hosoda, K Takano, T Nishida, Y Kobayashi, Y Takaku, N Takayanagi, S Ueda, A Tada, M Miyawaki, M Yamamoto, E Yoshida, R Hayashi, T Nagasaka, S Arai, Y Kaneko, K Sasaki, E Tagaya, M Kawana, K Arimura, K Takahashi, T Anzai, S Ito, A Endo, Y Uchimura, Y Miyazaki, T Honda, T Tateishi, S Tohda, N Ichimura, K Sonobe, CT Sassa, J Nakajima, Y Nakano, Y Nakajima, R Anan, R Arai, Y Kurihara, Y Harada, K Nishio, T Ueda, M Azuma, R Saito, T Sado, Y Miyazaki, R Sato, Y Haruta, T Nagasaki, Y Yasui, Y Hasegawa, Y Mutoh, T Kimura, T Sato, R Takei, S Hagimoto, Y Noguchi, Y Yamano, H Sasano, S Ota, Y Nakamori, K Yoshiya, F Saito, T Yoshihara, D Wada, H Iwamura, S Kanayama, S Maruyama, T Yoshiyama, K Ohta, H Kokuto, H Ogata, Y Tanaka, K Arakawa, M Shimoda, T Osawa, H Tateno, I Hase, S Yoshida, S Suzuki, M Kawada, H Horinouchi, F Saito, K Mitamura, M Hagihara, J Ochi, T Uchida, R Baba, D Arai, T Ogura, H Takahashi, S Hagiwara, G Nagao, S Konishi, I Nakachi, K Murakami, M Yamada, H Sugiura, H Sano, S Matsumoto, N Kimura, Y Ono, H Baba, Y Suzuki, S Nakayama, K Masuzawa, S Namba, K Suzuki, Y Naito, YC Liu, A Takuwa, F Sugihara, JB Wing, S Sakakibara, N Hizawa, T Shiroyama, S Miyawaki, Y Kawamura, A Nakayama, H Matsuo, Y Maeda, T Nii, Y Noda, T Niitsu, Y Adachi, T Enomoto, S Amiya, R Hara, Y Yamaguchi, T Murakami, T Kuge, K Matsumoto, Y Yamamoto, M Yamamoto, M Yoneda, T Kishikawa, S Yamada, S Kawabata, N Kijima, M Takagaki, N Sasa, Y Ueno, M Suzuki, N Takemoto, H Eguchi, T Fukusumi, T Imai, M Fukushima, H Kishima, H Inohara, K Tomono, K Kato, M Takahashi, F Matsuda, H Hirata, Y Takeda, H Koh, T Manabe, Y Funatsu, F Ito, T Fukui, K Shinozuka, S Kohashi, M Miyazaki, T Shoko, M Kojima, T Adachi, M Ishikawa, K Takahashi, T Inoue, T Hirano, K Kobayashi, H Takaoka, K Watanabe, N Miyazawa, Y Kimura, R Sado, H Sugimoto, A Kamiya, N Kuwahara, A Fujiwara, T Matsunaga, Y Sato, T Okada, Y Hirai, H Kawashima, A Narita, K Niwa, Y Sekikawa, K Nishi, M Nishitsuji, M Tani, J Suzuki, H Nakatsumi, T Ogura, H Kitamura, E Hagiwara, K Murohashi, H Okabayashi, T Mochimaru, S Nukaga, R Satomi, Y Oyamada, N Mori, T Baba, Y Fukui, M Odate, S Mashimo, Y Makino, K Yagi, M Hashiguchi, J Kagyo, T Shiomi, S Fuke, H Saito, T Tsuchida, S Fujitani, M Takita, D Morikawa, T Yoshida, T Izumo, M Inomata, N Kuse, N Awano, M Tone, A Ito, Y Nakamura, K Hoshino, J Maruyama, H Ishikura, T Takata, T Odani, M Amishima, T Hattori, Y Shichinohe, T Kagaya, T Kita, K Ohta, S Sakagami, K Koshida, K Hayashi, T Shimizu, Y Kozu, H Hiranuma, Y Gon, N Izumi, K Nagata, K Ueda, R Taki, S Hanada, K Kawamura, K Ichikado, K Nishiyama, H Muranaka, K Nakamura, N Hashimoto, K Wakahara, K Sakamoto, N Omote, A Ando, N Kodama, Y Kaneyama, S Maeda, T Kuraki, T Matsumoto, K Yokote, TA Nakada, R Abe, T Oshima, T Shimada, M Harada, T Takahashi, H Ono, T Sakurai, T Shibusawa, Y Kimizuka, A Kawana, T Sano, C Watanabe, R Suematsu, H Sageshima, A Yoshifuji, K Ito, S Takahashi, K Ishioka, M Nakamura, M Masuda, A Wakabayash, H Watanabe, S Ueda, M Nishikawa, Y Chihara, M Takeuchi, K Onoi, J Shinozuka, A Sueyoshi, Y Nagasaki, M Okamoto, S Ishihara, M Shimo, Y Tokunaga, Y Kusaka, T Ohba, S Isogai, A Ogawa, T Inoue, S Fukuyama, Y Eriguchi, A Yonekawa, K Kan-O, K Matsumoto, K Kanaoka, S Ihara, K Komuta, Y Inoue, S Chiba, K Yamagata, Y Hiramatsu, H Kai, K Asano, T Oguma, Y Ito, S Hashimoto, M Yamasaki, Y Kasamatsu, Y Komase, N Hida, T Tsuburai, B Oyama, M Takada, H Kanda, Y Kitagawa, T Fukuta, T Miyake, S Yoshida, S Ogura, S Abe, Y Kono, Y Togashi, H Takoi, R Kikuchi, S Ogawa, T Ogata, S Ishihara, A Kanehiro, S Ozaki, Y Fuchimoto, S Wada, N Fujimoto, K Nishiyama, M Terashima, S Beppu, K Yoshida, O Narumoto, H Nagai, N Ooshima, M Motegi, A Umeda, K Miyagawa, H Shimada, M Endo, Y Ohira, M Watanabe, S Inoue, A Igarashi, M Sato, H Sagara, A Tanaka, S Ohta, T Kimura, Y Shibata, Y Tanino, T Nikaido, H Minemura, Y Sato, Y Yamada, T Hashino, M Shinoki, H Iwagoe, H Takahashi, K Fujii, H Kishi, M Kanai, T Imamura, T Yamashita, M Yatomi, T Maeno, S Hayashi, M Takahashi, M Kuramochi, I Kamimaki, Y Tominaga, T Ishii, M Utsugi, A Ono, T Tanaka, T Kashiwada, K Fujita, Y Saito, M Seike, H Watanabe, H Matsuse, N Kodaka, C Nakano, T Oshio, T Hirouchi, S Makino, M Egi, Biobank Ja, Y Omae, Y Nannya, T Ueno, K Katayama, M Ai, Y Fukui, A Kumanogoh, T Sato, N Hasegawa, K Tokunaga, M Ishii, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Y Okada DOCK2 is involved in the host genetics and biology of severe COVID-19 Nature, 2022-08-08;609(7928):754-760. 2022-08-08 [PMID: 35940203] (Bioassay, Human) |
Bioassay |
Human |
| S Leng, L Liu, W Xu, F Yang, J Du, L Ye, D Huang, L Zhang Inflammation down regulates stromal cell-derived factor 1alpha in the early phase of pulpitis Cytokine, 2022-08-02;158(0):155983. 2022-08-02 [PMID: 35930964] (Bioassay, Human) |
Bioassay |
Human |
| M Mastrogiov, P Vargas, T Rose, C Cuche, E Esposito, M Juzans, H Laude, A Schneider, M Bernard, S Goyard, C Renaudat, MN Ungeheuer, J Delon, A Alcover, V Di Bartolo The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration Science Advances, 2022-04-13;8(15):eabl5942. 2022-04-13 [PMID: 35417240] (Bioassay, Human) |
Bioassay |
Human |
| TA Burley, A Hesketh, G Bucca, E Kennedy, EE Ladikou, BP Towler, S Mitchell, CP Smith, C Fegan, R Johnston, A Pepper, C Pepper Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia Cancers, 2022-03-22;14(7):. 2022-03-22 [PMID: 35406371] (Bioassay, Human) |
Bioassay |
Human |
| J Xu, J Hu, S Idlett-Ali, L Zhang, K Caples, S Peddibhotl, M Reeves, C Zgheib, S Malany, KW Liechty Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing International Journal of Molecular Sciences, 2022-02-16;23(4):. 2022-02-16 [PMID: 35216311] (Bioassay, Human) |
Bioassay |
Human |
| ML Capitano, Y Sammour, J Ropa, M Legendre, N Mor-Vaknin, DM Markovitz DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Galphai signaling Journal of leukocyte biology, 2022-02-08;0(0):. 2022-02-08 [PMID: 35137444] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Fielding, A García-Gar, C Korn, S Gadomski, Z Fang, JL Reguera, JA Pérez-Simó, B Göttgens, S Méndez-Fer Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis Nature Communications, 2022-01-27;13(1):543. 2022-01-27 [PMID: 35087060] (ELISA Control, Mouse) |
ELISA Control |
Mouse |
| Wellemans V, Benhassou H, Fuselier E, Bellesort F, Dury S, Lebargy F, Dormoy V, Fichel C, Naour R, Gounni A, Lamkhioued B Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells. iScience, 2021-11-14;24(12):103433. 2021-11-14 [PMID: 34917892] (Bioassay, Human) |
Bioassay |
Human |
| T Radaszkiew, M Nosková, K Gömöryová, O Vondálová, KA Radaszkiew, M Picková, R Víchová, T Gybe?, K Kaiser, L Demková, L Ku?erová, T Bárta, D Pot?šil, Z Zdráhal, K Sou?ek, V Bryja RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy Elife, 2021-10-27;10(0):. 2021-10-27 [PMID: 34702444] (Bioassay, Human) |
Bioassay |
Human |
| LA Ridge, D Kewbank, D Schütz, R Stumm, PJ Scambler, S Ivins Dual role for CXCL12 signaling in semilunar valve development Cell Reports, 2021-08-24;36(8):109610. 2021-08-24 [PMID: 34433040] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Berrazouan, A Doucet, M Boisvert, F Barabé, F Aoudjit VLA-4 Induces Chemoresistance of T Cell Acute Lymphoblastic Leukemia Cells via PYK2-Mediated Drug Efflux Cancers, 2021-07-14;13(14):. 2021-07-14 [PMID: 34298726] (Bioassay, Human) |
Bioassay |
Human |
| Y Fu, Z Zhang, Z Yang, Y Jiang, X Han, J Xu, Z Chu, H Ding, S He, H Shang CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression Cell Reports, 2021-07-13;36(2):109344. 2021-07-13 [PMID: 34260905] (Bioassay, Human) |
Bioassay |
Human |
| K Bassand, L Metzinger, M Naïm, N Mouhoubi, O Haddad, V Assoun, N Zaïdi, O Sainte-Cat, A Butt, E Guyot, O Oudar, C Laguillier, A Sutton, N Charnaux, V Metzinger-, H Hlawaty miR-126-3p is essential for CXCL12-induced angiogenesis Journal of Cellular and Molecular Medicine, 2021-06-12;0(0):. 2021-06-12 [PMID: 34117709] (Bioassay, Rat) |
Bioassay |
Rat |
| A Yuzuriha, S Nakamura, N Sugimoto, S Kihara, M Nakagawa, T Yamamoto, K Sekiguchi, K Eto Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin &beta1-ILK-&beta-catenin-JUN axis Stem Cell Research, 2021-03-16;53(0):102287. 2021-03-16 [PMID: 33813173] (Bioassay, Human) |
Bioassay |
Human |
| W Feng, W Huang, J Chen, C Qiao, D Liu, X Ji, M Xie, T Zhang, Y Wang, M Sun, D Tian, D Fan, Y Nie, K Wu, L Xia CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3 Theranostics, 2021-01-01;11(6):2612-2633. 2021-01-01 [PMID: 33456563] (Bioassay, Human) |
Bioassay |
Human |
| JY Kim, HJ Kim, CW Jung, TS Lee, EH Kim, MJ Park CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer Cell Death & Disease, 2021-01-07;12(1):48. 2021-01-07 [PMID: 33414415] (Bioassay, Human) |
Bioassay |
Human |
| D Biasci, M Smoragiewi, CM Connell, Z Wang, Y Gao, JED Thaventhir, B Basu, L Magiera, TI Johnson, L Bax, A Gopinathan, C Isherwood, FA Gallagher, M Pawula, I Hudecova, D Gale, N Rosenfeld, P Barmpounak, EC Popa, R Brais, E Godfrey, F Mir, FM Richards, DT Fearon, T Janowitz, DI Jodrell CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response Proc Natl Acad Sci U S A, 2020-10-30;0(0):. 2020-10-30 [PMID: 33127761] (Bioassay, Human) |
Bioassay |
Human |
| A Fumagalli, J Heuninck, A Pizzoccaro, E Moutin, J Koenen, M Séveno, T Durroux, MP Junier, G Schlecht-L, F Bachelerie, D Schütz, R Stumm, MJ Smit, NC Guérineau, S Chaumont-D, P Marin The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication Nat Commun, 2020-09-25;11(1):4855. 2020-09-25 [PMID: 32978390] (Bioassay, Human) |
Bioassay |
Human |
| PR Norden, Z Sun, GE Davis Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles PLoS ONE, 2020-06-22;15(6):e0235116. 2020-06-22 [PMID: 32569321] (Bioassay, Human) |
Bioassay |
Human |
| J O'Dwyer, M Cullen, S Fattah, R Murphy, S Stefanovic, L Kovarova, M Pravda, V Velebny, A Heise, GP Duffy, SA Cryan Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1alpha Pharmaceutics, 2020-06-04;12(6):. 2020-06-04 [PMID: 32512712] (Bioassay, Human) |
Bioassay |
Human |
| J Lim, J Heo, H Ju, JW Shin, Y Kim, S Lee, HY Yu, CM Ryu, H Yun, S Song, KS Hong, HM Chung, HR Kim, JS Roe, K Choi, IG Kim, EM Jeong, DM Shin Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway Sci Adv, 2020-04-15;6(16):eaba1334. 2020-04-15 [PMID: 32490200] (Bioassay, Human) |
Bioassay |
Human |
| H Levy-Baraz, L Shachnai-P, G Rodionov, A Saar, M Rosenzwaig, L Gez, A Rodin, N Marelly, M Abraham, I Mishalian, H Wildbaum, T Katz, Y Baar, S Yarkoni, R Bakimer-Kl, A Peled, T Zuckerman, J Stein Brief ex vivo Fas-ligand incubation attenuates GvHD without compromising stem cell graft performance Bone Marrow Transplant., 2020-05-20;0(0):. 2020-05-20 [PMID: 32433499] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Cho, BL Macklin, YY Lin, L Zhou, MJ Lai, G Lee, S Gerecht, EJ Duh iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina JCI Insight, 2020-03-26;5(6):. 2020-03-26 [PMID: 32213707] (Cell Culture, Human) |
Cell Culture |
Human |
| Y Wang, H Zhang, H He, K Ai, W Yu, X Xiao, Y Qin, L Zhang, H Xiong, G Zhou LRCH1 suppresses migration of CD4+ T cells and refers to disease activity in ulcerative colitis Int J Med Sci, 2020-02-17;17(5):599-608. 2020-02-17 [PMID: 32210709] (Bioassay, Human) |
Bioassay |
Human |
| AA Chimote, VS Gawali, HS Newton, TM Wise-Drape, L Conforti A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer Front Pharmacol, 2020-02-28;11(0):143. 2020-02-28 [PMID: 32184726] (Bioassay, Human) |
Bioassay |
Human |
| H Iseoka, S Miyagawa, A Saito, A Harada, Y Sawa Role and therapeutic effects of skeletal muscle-derived non-myogenic cells in a rat myocardial infarction model Stem Cell Res Ther, 2020-02-18;11(1):69. 2020-02-18 [PMID: 32070429] (Bioassay, Human) |
Bioassay |
Human |
| LA Callender, EC Carroll, EA Bober, AN Akbar, E Solito, SM Henson Mitochondrial mass governs the extent of human T cell senescence Aging Cell, 2019-12-02;0(0):e13067. 2019-12-02 [PMID: 31788930] (Bioassay, Human) |
Bioassay |
Human |
| PD Fromm, PA Silveira, JL Hsu, MS Papadimitr, TH Lo, X Ju, F Kupresanin, A Romano, WH Hsu, CE Bryant, B Kong, E Abadir, A Mekkawy, H M McGuire, BFS Groth, I Cunningham, E Newman, J Gibson, PM Hogarth, DNJ Hart, GJ Clark Distinguishing human peripheral blood CD16+ myeloid cells based on phenotypic characteristics J. Leukoc. Biol., 2019-11-21;0(0):. 2019-11-21 [PMID: 31749181] (Bioassay, Human) |
Bioassay |
Human |
| F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3) Int J Mol Sci, 2019-10-24;20(21):. 2019-10-24 [PMID: 31653015] (Bioassay, Human) |
Bioassay |
Human |
| NM Belle, Y Ji, K Herbine, Y Wei, J Park, K Zullo, LY Hung, S Srivatsa, T Young, T Oniskey, C Pastore, W Nieves, M Somsouk, DR Herbert TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths Nat Commun, 2019-09-27;10(1):4408. 2019-09-27 [PMID: 31562318] (Bioassay, Human) |
Bioassay |
Human |
| J Yang, L Zhang, Z Jiang, C Ge, F Zhao, J Jiang, H Tian, T Chen, H Xie, Y Cui, M Yao, H Li, J Li TCF12 promotes the tumorigenesis and metastasis of hepatocellular carcinoma via upregulation of CXCR4 expression Theranostics, 2019-08-12;9(20):5810-5827. 2019-08-12 [PMID: 31534521] (Bioassay, Human) |
Bioassay |
Human |
| L Chen, J Ouyang, K Wienand, K Bojarczuk, Y Hao, B Chapuy, D Neuberg, P Juszczynsk, LN Lawton, SJ Rodig, S Monti, MA Shipp CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas Haematologica, 2019-08-30;105(5):1361-1368. 2019-08-30 [PMID: 31471373] (Functional Assay, Human) |
Functional Assay |
Human |
| C Ieranò, C D'Alterio, S Giarra, M Napolitano, G Rea, L Portella, A Santagata, AM Trotta, A Barbieri, V Campani, A Luciano, C Arra, AM Anniciello, G Botti, L Mayol, G De Rosa, R Pacelli, S Scala CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells Cell Death Dis, 2019-07-22;10(8):562. 2019-07-22 [PMID: 31332163] (In Vivo, Migration, Mouse) |
In Vivo, Migration |
Mouse |
| DJ Wessels, N Pradhan, YN Park, MA Klepitsch, DF Lusche, KJ Daniels, KD Conway, ER Voss, SV Hegde, TP Conway, DR Soll Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment PLoS ONE, 2019-06-24;14(6):e0218854. 2019-06-24 [PMID: 31233557] (Bioassay, Cell Culture, Positive Control, Human) |
Bioassay, Cell Culture, Positive Control |
Human |
| ML Capitano, N Mor-Vaknin, AK Saha, S Cooper, M Legendre, H Guo, R Contreras-, F Kappes, MA Sartor, CT Lee, X Huang, DM Markovitz, HE Broxmeyer Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling J. Clin. Invest., 2019-05-20;130(0):2555-2570. 2019-05-20 [PMID: 31107242] (Bioassay, Mouse) |
Bioassay |
Mouse |
| W Liu, X Wang, S Wang, X Ba, T Xu, X Wang, X Zeng RhoGDI2 positively regulates the Rho GTPases activation in response to the ?2 outside-in signaling in T cells adhesion and migration on ICAM-1 J. Leukoc. Biol., 2019-05-10;0(0):. 2019-05-10 [PMID: 31075185] (Bioassay, Human) |
Bioassay |
Human |
| S Li, KW Fong, G Gritsina, A Zhang, JC Zhao, J Kim, A Sharp, W Yuan, C Aversa, XJ Yang, PS Nelson, FY Feng, AM Chinnaiyan, JS de Bono, C Morrissey, MB Rettig, J Yu Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer Cancer Res., 2019-04-05;0(0):. 2019-04-05 [PMID: 30952632] (Bioassay, Human) |
Bioassay |
Human |
| MR Blatchley, F Hall, S Wang, HC Pruitt, S Gerecht Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis Sci Adv, 2019;5(3):eaau7518. 2019 [PMID: 30906859] (Bioassay, Mouse) |
Bioassay |
Mouse |
| MJ Costa, J Kudaravall, JT Ma, WH Ho, K Delaria, C Holz, A Stauffer, AG Chunyk, Q Zong, E Blasi, B Buetow, TT Tran, K Lindquist, M Dorywalska, A Rajpal, DL Shelton, P Strop, SH Liu Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates Sci Rep, 2019-02-21;9(1):2443. 2019-02-21 [PMID: 30792442] (Bioassay, Human) |
Bioassay |
Human |
| LF Pavon, TT Sibov, AV de Souza, EF da Cruz, SMF Malheiros, FR Cabral, JG de Souza, P Boufleur, DM de Oliveir, SRC de Toledo, LC Marti, JM Malheiros, FF Paiva, A Tannús, SM de Oliveir, AM Chudzinski, MA de Paiva N, S Cavalheiro Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo Stem Cell Res Ther, 2018-11-09;9(1):310. 2018-11-09 [PMID: 30413179] (Bioassay, Human) |
Bioassay |
Human |
| JE Yoon, Y Kim, S Kwon, M Kim, YH Kim, JH Kim, TJ Park, HY Kang Senescent fibroblasts drive ageing pigmentation: ?A potential therapeutic target for senile lentigo Theranostics, 2018-09-09;8(17):4620-4632. 2018-09-09 [PMID: 30279727] (Bioassay, Human) |
Bioassay |
Human |
| S Mamand, RL Allchin, MJ Ahearne, SD Wagner Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma Sci Rep, 2018-09-21;8(1):14216. 2018-09-21 [PMID: 30242208] (Human) |
|
Human |
| Y Bao, Z Wang, B Liu, X Lu, Y Xiong, J Shi, P Li, J Chen, Z Zhang, M Chen, L Wang, Z Wu A feed-forward loop between nuclear translocation of CXCR4 and HIF-1? promotes renal cell carcinoma metastasis Oncogene, 2018-09-03;0(0):. 2018-09-03 [PMID: 30177838] (Bioassay, Human) |
Bioassay |
Human |
| W He, T Yang, XH Gong, RZ Qin, XD Zhang, WD Liu Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells Oncol Lett, 2018-07-04;16(3):3976-3982. 2018-07-04 [PMID: 30128017] (Bioassay, Human) |
Bioassay |
Human |
| T Ohta, C Monzel, AS Becker, AD Ho, M Tanaka Simple Physical Model Unravels Influences of Chemokine on Shape Deformation and Migration of Human Hematopoietic Stem Cells Sci Rep, 2018-07-13;8(1):10630. 2018-07-13 [PMID: 30006633] (Bioassay, Human) |
Bioassay |
Human |
| BL Benson, L Li, JT Myers, RD Dorand, UA Gurkan, AY Huang, RM Ransohoff Biomimetic post-capillary venule expansions for leukocyte adhesion studies Sci Rep, 2018-06-19;8(1):9328. 2018-06-19 [PMID: 29921896] |
|
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| F Jahan, S Madhavan, T Rolova, L Viazmina, M Grönholm, CG Gahmberg Phosphorylation of the ?-chain in the integrin LFA-1 enables ?2-chain phosphorylation and ?-actinin binding required for cell adhesion J. Biol. Chem., 2018-06-14;0(0):. 2018-06-14 [PMID: 29903913] (Bioassay) |
Bioassay |
|
| Y Nam, SM Jung, YA Rim, H Jung, K Lee, N Park, J Kim, Y Jang, YB Park, SH Park, JH Ju Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis PLoS ONE, 2018-06-07;13(6):e0198740. 2018-06-07 [PMID: 29879214] (Bioassay, Human) |
Bioassay |
Human |
| S Giarra, C Ierano, M Biondi, M Napolitano, V Campani, R Pacelli, S Scala, G De Rosa, L Mayol Engineering of thermoresponsive gels as a fake metastatic niche Carbohydr Polym, 2018-03-10;191(0):112-118. 2018-03-10 [PMID: 29661298] (Bioassay, Human) |
Bioassay |
Human |
| KM Dvorak, KM Pettee, K Rubinic-Mi, R Su, A Nestor-Kal, KM Eisenmann Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2) PLoS ONE, 2018-03-29;13(3):e0195278. 2018-03-29 [PMID: 29596520] (Bioassay, Human) |
Bioassay |
Human |
| SYN Jamaludin, I Azimi, FM Davis, AA Peters, TJ Gonda, EW Thompson, SJ Roberts-Th, GR Monteith Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells Oncol Lett, 2018-01-19;15(4):4289-4295. 2018-01-19 [PMID: 29541196] (Bioassay, Human) |
Bioassay |
Human |
| H Sun, F Lagarrigue, AR Gingras, Z Fan, K Ley, MH Ginsberg Transmission of integrin ?7 transmembrane domain topology enables gut lymphoid tissue development J. Cell Biol., 2018-03-13;0(0):. 2018-03-13 [PMID: 29535192] (Bioassay, Human) |
Bioassay |
Human |
| JL Rojo, M Linari, KA Young, MC Peluffo Stromal-derived factor 1 directly promotes genes expressed within the ovulatory cascade in feline cumulus oocyte complexes J. Assist. Reprod. Genet., 2018-03-08;0(0):. 2018-03-08 [PMID: 29516335] (Bioassay, Feline) |
Bioassay |
Feline |
| S Patalano, J Rodríguez-, C Colaneri, J Cotellessa, D Almanza, A Zhilin-Rot, T Riley, J Macoska CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation Sci Rep, 2018-02-22;8(1):3499. 2018-02-22 [PMID: 29472636] (Bioassay, Human) |
Bioassay |
Human |
| W Tang, SG Smith, W Du, A Gugilla, J Du, JP Oliveria, K Howie, BM Salter, GM Gauvreau, PM O'Byrne, R Sehmi Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma Clin Transl Allergy, 2018-02-13;8(0):5. 2018-02-13 [PMID: 29456832] (Bioassay, Human) |
Bioassay |
Human |
| TI Moore, J Aaron, TL Chew, TA Springer Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy Cell Rep, 2018-02-13;22(7):1903-1912. 2018-02-13 [PMID: 29444440] (Bioassay, Human) |
Bioassay |
Human |
| E Vågesjö, E Öhnstedt, A Mortier, H Lofton, F Huss, P Proost, S Roos, M Phillipson Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria Proc. Natl. Acad. Sci. U.S.A., 2018-02-05;0(0):. 2018-02-05 [PMID: 29432190] (In Vivo, Mouse) |
In Vivo |
Mouse |
| JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation Stem Cell Res, 2018-01-04;27(0):46-56. 2018-01-04 [PMID: 29324254] (Bioassay, Human) |
Bioassay |
Human |
| A Drouillard, A Neyra, AL Mathieu, A Marçais, M Wencker, J Marvel, A Belot, T Walzer Human Naive and Memory T Cells Display Opposite Migratory Responses to Sphingosine-1 Phosphate J. Immunol., 2017-12-13;0(0):. 2017-12-13 [PMID: 29237776] (Bioassay, Human) |
Bioassay |
Human |
| W Oliva-Oliv, I Moreno-Ind, L Coín-Aragü, S Lhamyani, J Alcaide To, S Fernández-, J Vendrell, A Camargo, R El Bekay, FJ Tinahones Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome PLoS ONE, 2017-11-22;12(11):e0188324. 2017-11-22 [PMID: 29166648] (Bioassay, Human) |
Bioassay |
Human |
| H Plešingero, P Janovská, A Mishra, L Smy?ková, L Poppová, A Libra, K Plevová, P Ovesná, L Radová, M Doubek, Š Pavlová, Š Pospíšilov, V Bryja Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia Haematologica, 2017-11-09;0(0):. 2017-11-09 [PMID: 29122990] (Bioassay, Human) |
Bioassay |
Human |
| Z Jiang, Y Li, X Ji, Y Tang, H Yu, L Ding, M Yu, Q Cui, M Zhang, Y Ma, M Li Protein profiling identified key chemokines that regulate the maintenance of human pluripotent stem cells Sci Rep, 2017-11-06;7(1):14510. 2017-11-06 [PMID: 29109449] (Bioassay, Human) |
Bioassay |
Human |
| XJ Li, P Liu, WW Tian, ZF Li, BG Liu, JF Sun Mechanisms of CXCR7 induction in malignant melanoma development Oncol Lett, 2017-08-04;14(4):4106-4114. 2017-08-04 [PMID: 28943917] (Bioassay, Human) |
Bioassay |
Human |
| S Park, H Jang, BS Kim, C Hwang, GS Jeong, Y Park Directional migration of mesenchymal stem cells under an SDF-1? gradient on a microfluidic device PLoS ONE, 2017-09-08;12(9):e0184595. 2017-09-08 [PMID: 28886159] (Bioassay, Human) |
Bioassay |
Human |
| X Liu, Y Liu, X Huang, G Lin, C Xie Endothelial progenitor cell dysfunction in acute exacerbation of chronic obstructive pulmonary disease Mol Med Rep, 2017-08-16;0(0):. 2017-08-16 [PMID: 28849108] (Bioassay, Human) |
Bioassay |
Human |
| D Kobayashi, M Endo, H Ochi, H Hojo, M Miyasaka, H Hayasaka Regulation of CCR7-dependent cell migration through�CCR7 homodimer formation Sci Rep, 2017-08-17;7(1):8536. 2017-08-17 [PMID: 28819198] (Bioassay, Human) |
Bioassay |
Human |
| M Zhang, L Qiu, Y Zhang, D Xu, JC Zheng, L Jiang CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells Sci Rep, 2017-08-15;7(1):8289. 2017-08-15 [PMID: 28811579] (Bioassay, Human) |
Bioassay |
Human |
| M Veenstra, DW Williams, TM Calderon, K Anastos, S Morgello, JW Berman Frontline Science: CXCR7 mediates CD14(+)CD16(+) monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS J. Leukoc. Biol., 2017-07-28;0(0):. 2017-07-28 [PMID: 28754798] (Bioassay, Human) |
Bioassay |
Human |
| PJ Stewart-Hu, TP Szasz, ER Jaeger, MD Onken, JA Cooper, SC Morley Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate J. Leukoc. Biol., 2017-06-21;0(0):. 2017-06-21 [PMID: 28637896] (Bioassay, Mouse) |
Bioassay |
Mouse |
| E Crompot, M Van Damme, K Pieters, M Vermeersch, D Perez-Morg, P Mineur, M Maerevoet, N Meuleman, D Bron, L Lagneaux, B Stamatopou Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B-cells from apoptosis, enhance their migration and induce gene expression modifications Haematologica, 2017-06-08;0(0):. 2017-06-08 [PMID: 28596280] (Bioassay, Human) |
Bioassay |
Human |
| JH Kim, JW Shim, DY Eum, SD Kim, SH Choi, K Yang, K Heo, MT Park Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells Sci Rep, 2017-06-05;7(1):2798. 2017-06-05 [PMID: 28584306] (Bioassay, Human) |
Bioassay |
Human |
| R Desplantes, C Lévêque, B Muller, M Lotierzo, G Ferracci, M Popoff, M Seagar, R Mamoun, O El Far Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor Sci Rep, 2017-04-21;7(1):1032. 2017-04-21 [PMID: 28432329] (Bioassay, Human) |
Bioassay |
Human |
| H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis PLoS ONE, 2017-04-18;12(4):e0176110. 2017-04-18 [PMID: 28419144] (Bioassay, Human) |
Bioassay |
Human |
| DI Bromage, S Taferner, M Pillai, DM Yellon, SM Davidson A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies PLoS ONE, 2017-04-05;12(4):e0174447. 2017-04-05 [PMID: 28379992] (ELISA (Standard), Enzyme Assay, Human) |
ELISA (Standard), Enzyme Assay |
Human |
| J Xu, J Liang, YM Meng, J Yan, XJ Yu, CQ Liu, L Xu, SM Zhuang, L Zheng Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma Clin. Cancer Res, 2017-02-21;0(0):. 2017-02-21 [PMID: 28223275] (Bioassay, Human) |
Bioassay |
Human |
| MT Logun, NS Bisel, EA Tanasse, W Zhao, B Gunasekera, L Mao, L Karumbaiah Glioma Cell Invasion is Significantly Enhanced in Composite Hydrogel Matrices Composed of Chondroitin 4- and 4,6-Sulfated Glycosaminoglycans J Mater Chem B Mater Biol Med, 2016-08-26;4(36):6052-6064. 2016-08-26 [PMID: 28217304] (Bioassay, Human) |
Bioassay |
Human |
| W Chen, S Ju, T Lu, Y Xu, X Zheng, H Wang, Y Ge, S Ju Directional delivery of RSPO1 by mesenchymal stem cells ameliorates radiation-induced intestinal injury Cytokine, 2017-02-20;95(0):27-34. 2017-02-20 [PMID: 28214675] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Strazza, I Azoulay-Al, M Peled, AV Smrcka, EY Skolnik, S Srivastava, A Mor PLC?1 regulates SDF-1?-induced lymphocyte adhesion and migration to sites of inflammation Proc. Natl. Acad. Sci. U.S.A, 2017-02-17;0(0):. 2017-02-17 [PMID: 28213494] (Bioassay, Human) |
Bioassay |
Human |
| M Moslem, R Eggenschwi, C Wichmann, R Buhmann, T Cantz, R Henschler Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells Stem Cells Int, 2017-01-09;2017(0):7316354. 2017-01-09 [PMID: 28163724] (Bioassay, Human) |
Bioassay |
Human |
| C Wang, MD Wang, P Cheng, H Huang, W Dong, WW Zhang, PP Li, C Lin, ZY Pan, MC Wu, WP Zhou Hepatitis B virus X protein promotes the stem-like properties of OV6(+) cancer cells in hepatocellular carcinoma Cell Death Dis, 2017-01-19;8(1):e2560. 2017-01-19 [PMID: 28102846] (Bioassay, Human) |
Bioassay |
Human |
| M Müller, S Ausländer, A Spinnler, D Ausländer, J Sikorski, M Folcher, M Fussenegge Designed cell consortia as fragrance-programmable analog-to-digital converters Nat. Chem. Biol, 2017-01-16;0(0):. 2017-01-16 [PMID: 28092361] (Bioassay, Human) |
Bioassay |
Human |
| MicroRNA expression profiles and networks in CXCL12?stimulated human endometrial stromal cells Mol Med Rep, 2016-12-07;15(1):249-255. 2016-12-07 [PMID: 27959395] (Bioassay, Human) |
Bioassay |
Human |
| Renren Bai Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library Eur J Med Chem, 2016-11-24;126(0):464-475. 2016-11-24 [PMID: 27914361] (Bioassay, Human) |
Bioassay |
Human |
| Amber N Stratman Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta Development, 2016-12-02;0(0):. 2016-12-02 [PMID: 27913637] (Bioassay, Human) |
Bioassay |
Human |
| SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia Sci Rep, 2016-10-07;6(0):34416. 2016-10-07 [PMID: 27713493] (Bioassay, Human) |
Bioassay |
Human |
| Xudong Shi Local CXCR4 Up-regulation in Injured Arterial Wall Contributes to Intimal Hyperplasia Stem Cells, 2016-07-17;0(0):. 2016-07-17 [PMID: 27340942] (Bioassay, Rat) |
Bioassay |
Rat |
| Patricia Freund Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation PLoS ONE, 2016-06-01;11(6):e0156693. 2016-06-01 [PMID: 27248492] (Bioassay, Human) |
Bioassay |
Human |
| Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: Evidence for Partial Allosteric Agonism in Comparison to CXCL12 J Biol Chem, 2016-05-19;0(0):. 2016-05-19 [PMID: 27226569] (Bioassay, Human) |
Bioassay |
Human |
| HEREGULIN/ErbB3 SIGNALING ENHANCES CXCR4-DRIVEN Rac1 ACTIVATION AND BREAST CANCER CELL MOTILITY VIA HIF-1? Mol Cell Biol, 2016-07-14;0(0):. 2016-07-14 [PMID: 27185877] (Bioassay, Human) |
Bioassay |
Human |
| S Velasquez, S Malik, SE Lutz, E Scemes, EA Eugenin Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis J Immunol, 2016-04-13;0(0):. 2016-04-13 [PMID: 27076682] (Bioassay, Human) |
Bioassay |
Human |
| Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, Pospisilova S, Pavlova S, Bryja V Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia. Clin Cancer Res, 2015-08-03;22(2):459-69. 2015-08-03 [PMID: 26240275] (Bioassay, Human) |
Bioassay |
Human |
| Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med, 2015-04-20;21(5):530-6. 2015-04-20 [PMID: 25894825] (Bioassay, Human) |
Bioassay |
Human |
| Heinzmann D, Bangert A, Muller A, von Ungern-Sternberg S, Emschermann F, Schonberger T, Chatterjee M, Mack A, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer H, Katus H, Fischer G, May A, Kaya Z, Seizer P The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis. PLoS ONE, 2015-04-20;10(4):e0124606. 2015-04-20 [PMID: 25894208] (Bioassay, Human) |
Bioassay |
Human |
| Chang T, Poltoratsky V, Vancurova I Bortezomib inhibits expression of TGF-beta1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells. J Immunol, 2015-02-13;194(6):2942-53. 2015-02-13 [PMID: 25681335] (Bioassay, Human) |
Bioassay |
Human |
| Gottle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, Parras C, Kremer D, Hartung H, Cate H, Kury P Oligodendroglial maturation is dependent on intracellular protein shuttling. J Neurosci, 2015-01-21;35(3):906-19. 2015-01-21 [PMID: 25609610] (Bioassay, Human, Rat) |
Bioassay |
Human, Rat |
| Butschkau , Antje, Wagner , Nana-Mar, Genz , Berit, Vollmar , Brigitte Protein z exerts pro-angiogenic effects and upregulates CXCR4. PLoS ONE, 2014-12-04;9(12):e113554. 2014-12-04 [PMID: 25474349] (Bioassay, Human) |
Bioassay |
Human |
| Williams D, Anastos K, Morgello S, Berman J JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals. J Leukoc Biol, 2014-11-24;97(2):401-12. 2014-11-24 [PMID: 25420915] (Bioassay, Human) |
Bioassay |
Human |
| Chigaev A, Smagley Y, Sklar L Carbon monoxide down-regulates alpha4beta1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization. BMC Immunol, 2014-10-31;15(0):52. 2014-10-31 [PMID: 25367365] (Bioassay, Human) |
Bioassay |
Human |
| Watson H, Holley R, Langford-Smith K, Wilkinson F, van Kuppevelt T, Wynn R, Wraith J, Merry C, Bigger B Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I. J Biol Chem, 2014-10-30;289(52):36194-203. 2014-10-30 [PMID: 25359774] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Walsh T, Harper M, Poole A SDF-1alpha is a novel autocrine activator of platelets operating through its receptor CXCR4. Cell Signal, 2014-10-05;27(1):37-46. 2014-10-05 [PMID: 25283599] (Bioassay, Human) |
Bioassay |
Human |
| Mendes-Da-Cruz D, Brignier A, Asnafi V, Baleydier F, Messias C, Lepelletier Y, Bedjaoui N, Renand A, Smaniotto S, Canioni D, Milpied P, Balabanian K, Bousso P, Lepretre S, Bertrand Y, Dombret H, Ifrah N, Dardenne M, Macintyre E, Savino W, Hermine O Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors. PLoS ONE, 2014-07-28;9(7):e103405. 2014-07-28 [PMID: 25068647] (Bioassay, Human) |
Bioassay |
Human |
| Ray P, Stacer A, Fenner J, Cavnar S, Meguiar K, Brown M, Luker K, Luker G CXCL12-gamma in primary tumors drives breast cancer metastasis. Oncogene, 2014-06-09;34(16):2043-51. 2014-06-09 [PMID: 24909174] (Bioassay, Human) |
Bioassay |
Human |
| Boudot A, Kerdivel G, Lecomte S, Flouriot G, Desille M, Godey F, Leveque J, Tas P, Le Drean Y, Pakdel F COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration. BMC Cancer, 2014-06-06;14(0):407. 2014-06-06 [PMID: 24906407] (Bioassay, Human) |
Bioassay |
Human |
| Coggins N, Trakimas D, Chang S, Ehrlich A, Ray P, Luker K, Linderman J, Luker G CXCR7 controls competition for recruitment of beta-arrestin 2 in cells expressing both CXCR4 and CXCR7. PLoS ONE, 2014-06-04;9(6):e98328. 2014-06-04 [PMID: 24896823] (Bioassay, Human) |
Bioassay |
Human |
| Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells. J Biol Chem, 2014-04-16;289(22):15340-9. 2014-04-16 [PMID: 24739387] (Bioassay, Human) |
Bioassay |
Human |
| Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit M, Blanchet X, von Hundelshausen P, Weber C, Forssmann W, Henschler R Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev, 2014-05-27;23(16):1959-74. 2014-05-27 [PMID: 24708339] (Bioassay, Human) |
Bioassay |
Human |
| Krook M, Nicholls L, Scannell C, Chugh R, Thomas D, Lawlor E Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. Mol Cancer Res, 2014-03-20;12(6):953-64. 2014-03-20 [PMID: 24651452] (Bioassay, Human) |
Bioassay |
Human |
| Chen L, Advani S, Thai K, Kabir M, Sood M, Gibson I, Yuen D, Connelly K, Marsden P, Kelly D, Gilbert R, Advani A SDF-1/CXCR4 signaling preserves microvascular integrity and renal function in chronic kidney disease. PLoS ONE, 2014-03-17;9(3):e92227. 2014-03-17 [PMID: 24637920] (Bioassay, Human) |
Bioassay |
Human |
| Zucco L, Zhang Q, Kuliszewski M, Kandic I, Faughnan M, Stewart D, Kutryk M Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia. PLoS ONE, 2014-02-25;9(2):e89927. 2014-02-25 [PMID: 24587130] (Bioassay, Human) |
Bioassay |
Human |
| Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration. J Immunol, 2014-02-28;192(7):3390-8. 2014-02-28 [PMID: 24585879] (Bioassay, Human) |
Bioassay |
Human |
| Lo H, Lai T, Li C, Wu W TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways. Acta Pharmacol Sin, 2014-02-03;35(3):339-50. 2014-02-03 [PMID: 24487964] (Bioassay, Human) |
Bioassay |
Human |
| Gharaee-Kermani M, Mehra R, Robinson D, Wei J, Macoska J Complex cellular composition of solitary fibrous tumor of the prostate. Am J Pathol, 2014-01-13;184(3):732-9. 2014-01-13 [PMID: 24434011] (Bioassay, Human) |
Bioassay |
Human |
| Ruiz E, Oeztuerk-Winder F, Ventura J A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Nat Commun, 2014-01-01;5(0):3175. 2014-01-01 [PMID: 24430801] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
| Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter P, Schakel K, Tamassia N, Cassatella M slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells. Nat Commun, 2014-01-01;5(0):3029. 2014-01-01 [PMID: 24398631] (Bioassay, Human) |
Bioassay |
Human |
| Smith A, Bowers S, Stratman A, Davis G Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE, 2013-12-31;8(12):e85147. 2013-12-31 [PMID: 24391990] (Bioassay, Human) |
Bioassay |
Human |
| Hoque , Md Tamji, Windus , Louisa C, Lovitt , Carrie J, Avery , Vicky M PCaAnalyser: a 2D-image analysis based module for effective determination of prostate cancer progression in 3D culture. PLoS ONE, 2013-11-20;8(11):e79865. 2013-11-20 [PMID: 24278197] (Cell Culture, Human) |
Cell Culture |
Human |
| Hoellenriegel J, Zboralski D, Maasch C, Rosin N, Wierda W, Keating M, Kruschinski A, Burger J The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. Blood, 2013-11-25;123(7):1032-9. 2013-11-25 [PMID: 24277076] (Bioassay) |
Bioassay |
|
| Wen W, Xie S, Xin X, Geng M, Ding J, Chen Y Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro. Acta Pharmacol Sin, 2013-10-21;34(12):1554-9. 2013-10-21 [PMID: 24141568] (Cell Culture, Human) |
Cell Culture |
Human |
| Westerweel , Peter E, Teraa , Martin, Rafii , Shahin, Jaspers , Janneke, White , Ian A, Hooper , Andrea T, Doevendans , Pieter A, Verhaar , Marianne Impaired endothelial progenitor cell mobilization and dysfunctional bone marrow stroma in diabetes mellitus. PLoS ONE, 2013-03-28;8(3):e60357. 2013-03-28 [PMID: 23555959] (Bioassay, Human) |
Bioassay |
Human |
| Cheng , Cheng-Ch, Chang , Shing-Jy, Chueh , Yu-Neng, Huang , Tse-Shun, Huang , Po-Hsun, Cheng , Shu-Meng, Tsai , Tsung-Ne, Chen , Jaw-Wen, Wang , Hsei-Wei Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses. BMC Genomics, 2013-03-15;14(0):182. 2013-03-15 [PMID: 23496821] (Bioassay, Human) |
Bioassay |
Human |
| Akimoto , Keiko, Kimura , Kenichi, Nagano , Masumi, Takano , Shingo, To'a Salazar , Georgina, Yamashita , Toshihar, Ohneda , Osamu Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation. Stem Cells Dev, 2013-02-04;22(9):1370-86. 2013-02-04 [PMID: 23231075] (Bioassay, Human) |
Bioassay |
Human |
| Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration. Blood, 2012-10-16;121(2):403-15. 2012-10-16 [PMID: 23074273] (Bioassay, Human) |
Bioassay |
Human |
| Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia. BMC Cancer, 2012-09-26;12(0):431. 2012-09-26 [PMID: 23013471] (Bioassay, Human) |
Bioassay |
Human |
| Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 2012-07-26;487(7408):505-9. 2012-07-26 [PMID: 22763448] (Bioassay, Human) |
Bioassay |
Human |
| Tai Y, Chang B, Kong S, Fulciniti M, Yang G, Calle Y, Hu Y, Lin J, Zhao J, Cagnetta A, Cea M, Sellitto M, Zhong M, Wang Q, Acharya C, Carrasco D, Buggy J, Elias L, Treon S, Matsui W, Richardson P, Munshi N, Anderson K Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma. Blood, 2012-06-11;120(9):1877-87. 2012-06-11 [PMID: 22689860] (Bioassay, Human) |
Bioassay |
Human |
| Badr G, Lefevre EA, Mohany M Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE, 2011-09-01;6(9):e23741. 2011-09-01 [PMID: 21912642] (Bioassay, Human) |
Bioassay |
Human |
| Fujio M, Yamamoto A, Ando Y, Shohara R, Kinoshita K, Kaneko T, Hibi H, Ueda M Stromal cell-derived factor-1 enhances distraction osteogenesis-mediated skeletal tissue regeneration through the recruitment of endothelial precursors. Bone, 2011-06-29;49(4):693-700. 2011-06-29 [PMID: 21741502] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Fujita-Sato S, Ito S, Isobe T, Ohyama T, Wakabayashi K, Morishita K, Ando O, Isono F Structural basis of digoxin that antagonizes RORgamma t receptor activity and suppresses Th17 cell differentiation and interleukin (IL)-17 production. J. Biol. Chem., 2011-07-06;286(36):31409-17. 2011-07-06 [PMID: 21733845] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin. Cancer Res., 2011-04-11;17(11):3619-30. 2011-04-11 [PMID: 21482691] (Bioassay, Human) |
Bioassay |
Human |
| Benamar K, Palma J, Cowan A, Geller EB, Adler MW Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1alpha/CXCL12 in the brain. Drug Alcohol Depend, 2010-11-26;114(2):246-8. 2010-11-26 [PMID: 21112161] (In Vivo, Rat) |
In Vivo |
Rat |
| Burton VJ, Butler LM, McGettrick HM, Stone PC, Jeffery HC, Savage CO, Rainger GE, Nash GB Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture. Exp. Cell Res., 2010-11-04;317(3):276-92. 2010-11-04 [PMID: 21056557] (Bioassay, Human) |
Bioassay |
Human |
| Berahovich RD, Zabel BA, Penfold ME, Lewen S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ CXCR7 protein is not expressed on human or mouse leukocytes. J. Immunol., 2010-10-01;185(9):5130-9. 2010-10-01 [PMID: 20889540] (Binding Assay, Human) |
Binding Assay |
Human |
| Hachehouche LN, Chetoui N, Aoudjit F Implication of discoidin domain receptor 1 in T cell migration in three-dimensional collagen. Mol. Immunol., 2010-03-29;47(9):1866-9. 2010-03-29 [PMID: 20353877] (Bioassay, Human) |
Bioassay |
Human |
| Charles J, Di Domizio J, Salameire D, Bendriss-Vermare N, Aspord C, Muhammad R, Lefebvre C, Plumas J, Leccia MT, Chaperot L Characterization of circulating dendritic cells in melanoma: role of CCR6 in plasmacytoid dendritic cell recruitment to the tumor. J. Invest. Dermatol., 2010-03-11;130(6):1646-56. 2010-03-11 [PMID: 20220766] (Bioassay, Human) |
Bioassay |
Human |
| Sengupta N, Afzal A, Caballero S, Chang KH, Shaw LC, Pang JJ, Bond VC, Bhutto I, Baba T, Lutty GA, Grant MB Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Invest. Ophthalmol. Vis. Sci., 2009-12-10;51(5):2697-704. 2009-12-10 [PMID: 20007826] (Bioassay, Human) |
Bioassay |
Human |
| Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood, 2009-10-12;114(24):5091-101. 2009-10-12 [PMID: 19822899] (Bioassay, Human) |
Bioassay |
Human |
| Kenig S, Alonso MB, Mueller MM, Lah TT Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9. Cancer Lett., 2009-08-22;289(1):53-61. 2009-08-22 [PMID: 19700239] (Bioassay, Human) |
Bioassay |
Human |
| Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy. FASEB J., 2009-04-20;23(9):2928-41. 2009-04-20 [PMID: 19380511] (Bioassay, Human) |
Bioassay |
Human |
| Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med., 2009-03-09;206(3):535-48. 2009-03-09 [PMID: 19273625] (Bioassay, Human) |
Bioassay |
Human |
| Skrzeczynska-Moncznik J, Wawro K, Stefanska A, Oleszycka E, Kulig P, Zabel BA, Sulkowski M, Kapinska-Mrowiecka M, Czubak-Macugowska M, Butcher EC, Cichy J Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem. Biophys. Res. Commun., 2009-01-23;380(2):323-7. 2009-01-23 [PMID: 19168032] (Bioassay, Human) |
Bioassay |
Human |
| Crawford Y, Kasman I, Yu L, Zhong C, Wu X, Modrusan Z, Kaminker J, Ferrara N PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell, 2009-01-06;15(1):21-34. 2009-01-06 [PMID: 19111878] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Struyf S, Noppen S, Loos T, Mortier A, Gouwy M, Verbeke H, Huskens D, Luangsay S, Parmentier M, Geboes K, Schols D, Van Damme J, Proost P Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4. J. Immunol., 2009-01-01;182(1):666-74. 2009-01-01 [PMID: 19109200] (Bioassay, Human) |
Bioassay |
Human |
| Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 2008-12-01;181(11):8053-67. 2008-12-01 [PMID: 19017998] (Bioassay, Human) |
Bioassay |
Human |
| Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. Eur. J. Immunol., 2008-11-01;38(11):3050-9. 2008-11-01 [PMID: 18924211] (Bioassay, Human) |
Bioassay |
Human |
| Kerfoot SM, Andonegui G, Bonder CS, Liu L Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo. Am. J. Physiol. Heart Circ. Physiol., 2008-04-18;294(6):H2524-34. 2008-04-18 [PMID: 18424631] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature, 2007-12-06;450(7171):825-31. 2007-12-06 [PMID: 18064003] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Kaminski A, Ma N, Donndorf P, Lindenblatt N, Feldmeier G, Ong LL, Furlani D, Skrabal CA, Liebold A, Vollmar B, Steinhoff G Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells. Lab. Invest., 2007-11-26;88(1):58-69. 2007-11-26 [PMID: 18040270] (Bioassay, In Vivo, Mouse) |
Bioassay, In Vivo |
Mouse |
| Isakova IA, Baker K, Dutreil M, Dufour J, Gaupp D, Phinney DG Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain. Stem Cells, 2007-10-11;25(12):3261-70. 2007-10-11 [PMID: 17932418] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. J. Immunol., 2007-10-01;179(7):4661-71. 2007-10-01 [PMID: 17878364] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut. J. Clin. Invest., 2007-09-01;117(9):2526-38. 2007-09-01 [PMID: 17786243] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS, 2007;21(10):1263-72. 2007 [PMID: 17545702] (ELISA (Standard), N/A) |
ELISA (Standard) |
N/A |
| Bayry J, Triebel F, Kaveri SV, Tough DF Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J. Immunol., 2007-04-01;178(7):4184-93. 2007-04-01 [PMID: 17371975] (Bioassay, Human) |
Bioassay |
Human |
| Nakayama T, Mutsuga N, Tosato G FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood, 2006-10-31;109(4):1363-72. 2006-10-31 [PMID: 17077327] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. Blood, 2006-10-12;109(4):1381-6. 2006-10-12 [PMID: 17038526] (Bioassay, Human) |
Bioassay |
Human |
| Saunders WB, Bohnsack BL, Faske JB, Anthis NJ, Bayless KJ, Hirschi KK, Davis GE Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J. Cell Biol., 2006-10-09;175(1):179-91. 2006-10-09 [PMID: 17030988] (Bioassay, Human) |
Bioassay |
Human |
| Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia, 2006-11-01;54(6):619-29. 2006-11-01 [PMID: 16944452] (ELISA (Standard)) |
ELISA (Standard) |
|
| Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, Nagakubo D, Saito T, Shimomura Y, Yoshie O Novel antiviral activity of chemokines. Virology, 2006-04-17;350(2):484-92. 2006-04-17 [PMID: 16603217] (Binding Assay, Bioassay, Virus) |
Binding Assay, Bioassay |
Virus |
| Infantino S, Moepps B, Thelen M Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells. J. Immunol., 2006-02-15;176(4):2197-207. 2006-02-15 [PMID: 16455976] (ELISA (Standard)) |
ELISA (Standard) |
|
| Anghelina M, Krishnan P, Moldovan L, Moldovan NI Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles. Am. J. Pathol., 2006-02-01;168(2):529-41. 2006-02-01 [PMID: 16436667] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism. Cardiovasc. Res., 2006-01-10;69(4):925-35. 2006-01-10 [PMID: 16409996] (In Vivo, Rat) |
In Vivo |
Rat |
| Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan AI, Facchini A Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J. Cell. Physiol., 2006-05-01;207(2):364-73. 2006-05-01 [PMID: 16331675] (ELISA (Standard)) |
ELISA (Standard) |
|
| Corti S, Locatelli F, Papadimitriou D, Donadoni C, Del Bo R, Fortunato F, Strazzer S, Salani S, Bresolin N, Comi GP Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells. FASEB J., 2005-09-08;19(13):1860-2. 2005-09-08 [PMID: 16150803] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 2005-05-01;52(5):1504-16. 2005-05-01 [PMID: 15880822] (Bioassay, Human) |
Bioassay |
Human |
| Curiel , Tyler J, Coukos , George, Zou , Linhua, Alvarez , Xavier, Cheng , Pui, Mottram , Peter, Evdemon-Hogan , Melina, Conejo-Garcia , Jose R, Zhang , Lin, Burow , Matthew, Zhu , Yun, Wei , Shuang, Kryczek , Ilona, Daniel , Ben, Gordon , Alan, Myers , Leann, Lackner , Andrew, Disis , Mary L, Knutson , Keith L, Chen , Lieping, Zou , Weiping Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med, 2004-08-22;10(9):942-9. 2004-08-22 [PMID: 15322536] (Bioassay, Human) |
Bioassay |
Human |
| Levesque JP, Liu F, Simmons PJ, Betsuyaku T, Senior RM, Pham C, Link DC Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood, 2004-03-09;104(1):65-72. 2004-03-09 [PMID: 15010367] (ELISA (Standard)) |
ELISA (Standard) |
|
| Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol., 2004-01-20;2(1):E6. 2004-01-20 [PMID: 14737186] (Bioassay, Human) |
Bioassay |
Human |
| Villalba S, Salvucci O, Aoki Y, De La Luz Sierra M, Gupta G, Davis D, Wyvill K, Little R, Yarchoan R, Tosato G Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. J. Leukoc. Biol., 2003-07-22;74(5):880-8. 2003-07-22 [PMID: 12960279] (Bioassay, Control, ELISA (Standard), Western Blot, Human, Mouse) |
Bioassay, Control, ELISA (Standard), Western Blot |
Human, Mouse |
| Okuma K, Dalton KP, Buonocore L, Ramsburg E, Rose JK Development of a novel surrogate virus for human T-cell leukemia virus type 1: inhibition of infection by osteoprotegerin. J. Virol., 2003-08-01;77(15):8562-9. 2003-08-01 [PMID: 12857926] (Bioassay, Human) |
Bioassay |
Human |
| Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell, 2002-05-31;109(5):625-37. 2002-05-31 [PMID: 12062105] (Bioassay, Human) |
Bioassay |
Human |
| Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol., 2002-06-15;168(12):6244-52. 2002-06-15 [PMID: 12055238] (Bioassay, Human) |
Bioassay |
Human |
| Zamarchi R, 2019, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, Esposito G, Roni V, Paganin C, Bianchi G, Titti F, Verani P, Gerosa G, Amadori A Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes. 192, 2002-02-01;127(2):321-30. 2002-02-01 [PMID: 11876757] (Bioassay, Human) |
Bioassay |
Human |
| Misse D, Cerutti M, Noraz N, Jourdan P, Favero J, Devauchelle G, Yssel H, Taylor N, Veas F A CD4-independent interaction of human immunodeficiency virus-1 gp120 with CXCR4 induces their cointernalization, cell signaling, and T-cell chemotaxis. Blood, 1999-04-15;93(8):2454-62. 1999-04-15 [PMID: 10194422] (Bioassay, Human) |
Bioassay |
Human |
|
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![Immunohistochemistry CXCR4 Antibody (44716) [Unconjugated]](https://images.novusbio.com/images2/CXCR4_MAB172_Immunohistochemistry_19917.jpg)
![N/A VEGF [HRP]](https://images.novusbio.com/images2/DATA_VEGF_DVE00_ELISA_871.jpg)
![N/A VEGF [HRP]](https://images.novusbio.com/images2/DATA_VEGF_DVE00_ELISA_872.jpg)
![N/A VEGF [HRP]](https://images.novusbio.com/images2/VEGF_DVE00_ELISA_208.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/CCL2_DCP00_ELISA_67.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_633.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_634.jpg)
![Immunohistochemistry CD34 Antibody [Unconjugated]](https://images.novusbio.com/images2/CD34_AF4117_Immunohistochemistry_6824.jpg)
![N/A CCL5/RANTES [HRP]](https://images.novusbio.com/images2/CCL5_DRN00_ELISA_393.jpg)
![N/A CCL5/RANTES [HRP]](https://images.novusbio.com/images2/DATA_CCL5_DRN00_ELISA_810.jpg)
![N/A CCL5/RANTES [HRP]](https://images.novusbio.com/images2/DATA_CCL5_DRN00_ELISA_811.jpg)
![Western Blot ERK2 Antibody [Unconjugated]](https://images.novusbio.com/images2/ERK2_AF1230_Western_Blot_5097.jpg)
![Immunohistochemistry ERK2 Antibody [Unconjugated]](https://images.novusbio.com/images2/ERK2_AF1230_Immunohistochemistry_20696.jpg)
![Knockout Validated ERK2 Antibody [Unconjugated]](https://images.novusbio.com/images2/ERK2_AF1230_Knockout_Validated_22864.jpg)
![Flow Cytometry CCR5 Antibody (45531) [Unconjugated]](https://images.novusbio.com/images2/CCR5_MAB182_Flow_Cytometry_22407.jpg)
![Neutralization CCR5 Antibody (45531) [Unconjugated]](https://images.novusbio.com/images2/CCR5_MAB182_Block_Neutralize_9044.jpg)
![Immunocytochemistry CCR5 Antibody (45531) [Unconjugated]](https://images.novusbio.com/images2/CCR5_MAB182_Immunocytochemistry_9681.jpg)
![SDS-PAGE TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg)
![Bioactivity TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg)
![SEC-MALS TNF-alpha [Unconjugated]](https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/DATA_IL6_M6000_ELISA_936.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/IL-6_M6000_ELISA_415.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg)
![Immunohistochemistry CXCR7/RDC-1 Antibody (11G8) [Unconjugated]](https://images.novusbio.com/images2/CXCR7_MAB42273_Immunohistochemistry_22246.jpg)
![Flow Cytometry CXCR7/RDC-1 Antibody (11G8) [Unconjugated]](https://images.novusbio.com/images2/CXCR7_MAB42273_Flow_Cytometry_8444.jpg)
![Functional CXCR7/RDC-1 Antibody (11G8) [Unconjugated]](https://images.novusbio.com/images/mab42273_human-cxcr7-rdc-1-mab-clone-11g8-4120241252148.jpg)
![CCL21/6Ckine [Unconjugated]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "CCL21/6Ckine [Unconjugated]")
![Immunohistochemistry CXCL13/BLC/BCA-1 Antibody [Unconjugated]](https://images.novusbio.com/images2/CXCL13_AF470_Immunohistochemistry_10193.jpg)
![Neutralization CXCL13/BLC/BCA-1 Antibody [Unconjugated]](https://images.novusbio.com/images2/CXCL13_AF470_Block_Neutralize_8888.jpg)
![Simple Western DPPIV/CD26 Antibody [Unconjugated]](https://images.novusbio.com/images2/DPPIV_AF1180_Simple_Western_20720.jpg)
![Immunohistochemistry DPPIV/CD26 Antibody [Unconjugated]](https://images.novusbio.com/images2/DPPIV_AF1180_Immunohistochemistry_17209.jpg)
![Immunocytochemistry DPPIV/CD26 Antibody [Unconjugated]](https://images.novusbio.com/images2/DPPIV_AF1180_Immunocytochemistry__Immunofluorescence_17210.jpg)
![Immunohistochemistry CCR2 Antibody (48607) [Unconjugated]](https://images.novusbio.com/images2/CCR2_MAB150_Immunohistochemistry_18879.jpg)
![Flow Cytometry CCR2 Antibody (48607) [Unconjugated]](https://images.novusbio.com/images2/CCR2_MAB150_Flow_Cytometry_19981.jpg)